Title: 10 Best Spa Resorts in Mississippi for 2025 | Expedia.ca [Mississippi Travel Guide](https://expedia.ca/Mississippi.dx226)[Mississippi Hotels](https://expedia.ca/Destinations-In-Mississippi.d226.Hotel-Destinations)[Vacation Rentals in Mississippi](https://expedia.ca/Destinations-In-Mississippi.d226.Vacation-Rental-Destinations)[Mississippi Flights](https://expedia.ca/Destinations-In-Mississippi.d226.Flight-Destinations)[Mississippi Car Rentals](https://expedia.ca/Destinations-In-Mississippi.d226.Car-Rental-Destinations)[Mississippi Vacations](https://expedia.ca/Mississippi.d226.Destination-Travel-Guides) ![Jackson, Mississippi, USA Skyline.](https://images.trvl-media.com/place/226/a1e6017b-93a0-48e6-849c-9e1235278e86.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Mississippi Spa Resorts - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Mississippi ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/483000/483387-biloxi.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Biloxi [](https://expedia.ca/Biloxi-Hotels-Spa-Hotel.0-0-d603259-tSpaHotel.Travel-Guide-Filter-Hotels) ![Jackson which includes street scenes, an administrative building and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/147000/147532-Jackson-Mississippi.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Jackson [](https://expedia.ca/Jackson-Hotels-Spa-Hotel.0-0-d1670-tSpaHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/483000/483451-bayou-view.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Gulfport [](https://expedia.ca/Gulfport-Hotels-Spa-Hotel.0-0-d1372-tSpaHotel.Travel-Guide-Filter-Hotels) ![Vicksburg featuring a small town or village](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/134000/134748-Vicksburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Vicksburg [](https://expedia.ca/Vicksburg-Hotels-Spa-Hotel.0-0-d10272-tSpaHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/419000/419453-Mississippi-Gulf-Coast.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Hattiesburg [](https://expedia.ca/Hattiesburg-Hotels-Spa-Hotel.0-0-d6058670-tSpaHotel.Travel-Guide-Filter-Hotels) ![Natchez featuring signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/146000/146997-Natchez.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Natchez [](https://expedia.ca/Natchez-Hotels-Spa-Hotel.0-0-d7671-tSpaHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/485000/485510-jackson-county.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Ocean Springs [](https://expedia.ca/Ocean-Springs-Hotels-Spa-Hotel.0-0-d9238-tSpaHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/2/75678f53f88148f25772b0a5c214539d.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Starkville [](https://expedia.ca/Starkville-Hotels-Spa-Hotel.0-0-d6058675-tSpaHotel.Travel-Guide-Filter-Hotels) ## Check availability on Mississippi Spa Hotels Tonight [Nov 19 - Nov 20](https://www.expedia.ca/Hotel-Search?regionId=226&startDate=2025-11-19&endDate=2025-11-20&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 20 - Nov 21](https://www.expedia.ca/Hotel-Search?regionId=226&startDate=2025-11-20&endDate=2025-11-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=226&startDate=2025-11-21&endDate=2025-11-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=226&startDate=2025-11-28&endDate=2025-11-30&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mississippi Spa Hotels ![Reception](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/7c3027e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/6cab3dab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/89dcbeb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18420000/18411100/18411003/f28c478e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Jackson Downtown Jackson 9.2/10 Wonderful (815) "The Westin was in perfect location, the staff was friendly, and Valet was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ursula CA $220 CA $245 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Jackson-Hotels-The-Westin-Jackson.h18411003.Hotel-Information) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/e7ff60a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/364a95a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 bars/lounges, sports bar](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/fb7837f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 7:30 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/b66654c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beau Rivage Downtown Biloxi 9.2/10 Wonderful (1411) "Everything was beautiful I really enjoyed my stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Subertia CA $153 CA $205 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Biloxi-Hotels-Beau-Rivage.h199634.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/8419c524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/5cecdcbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/b0ef1168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Hearing)](https://images.trvl-media.com/lodging/73000000/72280000/72278600/72278514/819e1941.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Tupelo Tupelo 9.2/10 Wonderful (622) "Lovely stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carrie CA $139 CA $152 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Tupelo-Hotels-Tru-By-Hilton-Tupelo.h72278514.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598927/abb81802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598927/6266d921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598927/7cef7a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598927/4e43e467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Memphis/Southaven, MS Southaven 8.6/10 Excellent (1000) "Very nice place . Clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $128 CA $141 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Memphis-Hotels-Hilton-Garden-Inn-MemphisSouthaven.h1598927.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958793/969f44da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958793/f9830ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Two Queen Beds, Accessible](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958793/eb8dbee4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958793/bca898d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Jackson/Flowood (Airport Area) MS Flowood 9.0/10 Wonderful (1001) "Nice room and service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marco A CA $133 CA $149 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Jackson-Hotels-Hampton-Inn-JacksonFlowood.h2958793.Hotel-Information) ![3 restaurants, breakfast, lunch, dinner served; seafood](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/86740aab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/fd395576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Smoking](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/3923ebb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12690000/12685300/12685296/0d77dc8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Silver Slipper Casino & Hotel - Adults Only Bay St Louis 8.6/10 Excellent (1000) "Rooms were clean. Great location. Staff friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy CA $110 CA $120 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Biloxi-Hotels-Silver-Slipper-Casino-Hotel.h12685296.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45770000/45764800/45764716/783375ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free on-the-go breakfast](https://images.trvl-media.com/lodging/46000000/45770000/45764800/45764716/9485a76d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/46000000/45770000/45764800/45764716/06827afb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/46000000/45770000/45764800/45764716/86aa793b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Jackson/Pearl, MS Pearl 8.8/10 Excellent (858) "Wonderful A+ stay!!! Staff is so nice and welcoming!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $139 CA $155 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Jackson-Hotels-Home2-Suites-By-Hilton-JacksonPearl.h45764716.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/58000000/57790000/57787800/57787752/d13387bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/58000000/57790000/57787800/57787752/74bb001a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/58000000/57790000/57787800/57787752/5d17839d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/58000000/57790000/57787800/57787752/82cc7f29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel DeSoto Olive Branch 9.0/10 Wonderful (1147) "Pretty Good hotel and great location " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Pablo A [](https://www.expedia.ca/Olive-Branch-Hotels-Hotel-DeSoto.h57787752.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/46d9ec38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/d46b15da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/ef67498d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/5c34c1ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Oxford Oxford 9.2/10 Wonderful (900) "Nice place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hilary CA $125 CA $136 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Oxford-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oxford.h39577074.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557655/bff72e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557655/9df85b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557655/4ca21e3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557655/9718006a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express and Suites Winona North by IHG Winona 8.2/10 Very good (670) "Will stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MIKE CA $165 CA $180 total includes taxes & fees Nov 22 - Nov 23 [](https://www.expedia.ca/Grenada-Hotels-Holiday-Inn-Express-And-Suites-Winona-North.h3557655.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-03&endDate=2025-12-04®ionId=226&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Mississippi-Spa-Hotel.0-0-d226-tSpaHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Mississippi-Spa-Hotel.0-0-d226-tSpaHotel.Hotel-Filter-Destinations) ## Top Mississippi Hotel Reviews ![Golden Nugget Biloxi](https://images.trvl-media.com/lodging/1000000/30000/22300/22267/0e82f306_y.jpg) ### Golden Nugget Biloxi 10/10 Excellent "yes room was very clean " [](https://expedia.ca/Biloxi-Hotels-Golden-Nugget-Biloxi.h22267.Hotel-Information) ![IP Casino Resort Spa - Biloxi](https://images.trvl-media.com/lodging/1000000/90000/85100/85080/e0a1ead8_y.jpg) ### IP Casino Resort Spa - Biloxi 10/10 Excellent "I have been staying at the Golden Nugget for yeers and after several bad experiences decided to try the IP resort, what a lovely place. All the staff from front desk, restaurant and casino personal made you feel so comfortable and at home. The food at the steak house was exceptional and though a little pricey well worth the experience. I will certainly stay here again. " [](https://expedia.ca/Biloxi-Hotels-IP-Casino-Resort-Spa-Biloxi.h85080.Hotel-Information) ![Hard Rock Hotel & Casino Biloxi](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731566/7e1bb110_y.jpg) ### Hard Rock Hotel & Casino Biloxi 10/10 Excellent "Everyone and everything was amazing ! Loved my pool and Gulf view !! I did think my king room would have been larger but overall was fine. Did wish i had a nice tub and shower combo as i like to soak ! But shower was beautiful. Will stay again, just may get a different room type. " [](https://expedia.ca/Biloxi-Hotels-Hard-Rock-Hotel-Casino-Biloxi.h1731566.Hotel-Information) ![Beau Rivage](https://images.trvl-media.com/lodging/1000000/200000/199700/199634/b66654c5_y.jpg) ### Beau Rivage 10/10 Excellent "Yes" [](https://expedia.ca/Biloxi-Hotels-Beau-Rivage.h199634.Hotel-Information) ![Best Western Plus Desoto](https://images.trvl-media.com/lodging/56000000/55560000/55559600/55559519/86c98407_y.jpg) ### Best Western Plus Desoto 10/10 Excellent "clean room, excellent staff" [](https://expedia.ca/Olive-Branch-Hotels-Best-Western-Plus-Desoto.h55559519.Hotel-Information) ![Baymont by Wyndham Jackson/Ridgeland](https://images.trvl-media.com/lodging/1000000/540000/537200/537157/7b452194_y.jpg) ### Baymont by Wyndham Jackson/Ridgeland 10/10 Excellent "Everything was really nice. I would stay there again." [](https://expedia.ca/Jackson-Hotels-Baymont-By-Wyndham-JacksonRidgeland.h537157.Hotel-Information) ![Comfort Suites Gulfport](https://images.trvl-media.com/lodging/3000000/2960000/2958800/2958794/5de09bb8_y.jpg) ### Comfort Suites Gulfport 10/10 Excellent "Amazing staff " [](https://expedia.ca/Biloxi-Hotels-Comfort-Suites-Gulfport.h2958794.Hotel-Information) ![Hyatt Place Biloxi](https://images.trvl-media.com/lodging/17000000/16130000/16127500/16127483/482651a7_y.jpg) ### Hyatt Place Biloxi 10/10 Excellent "Really nice hotel and the staff is great! Bed was comfy with nice fluffy pillows and my room had a water view too!" [](https://expedia.ca/Biloxi-Hotels-Hyatt-Place-Biloxi.h16127483.Hotel-Information) ![Motel 6 Biloxi, MS - Beach](https://images.trvl-media.com/lodging/1000000/1000000/996200/996160/c051e826_y.jpg) ### Motel 6 Biloxi, MS - Beach 10/10 Excellent "A very nice surprise and very good value. 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