Mississippi Spa Resorts

Change your mind

Book hotels with free cancellation

Treat yourself

Be picky

Search almost a million properties worldwide

Top Cities in Mississippi

Check availability on Mississippi Spa Hotels

Tonight

Tomorrow

Next weekend

In two weeks

Top Mississippi Spa Hotels

Enjoy al fresco dining under the shade of large umbrellas at this hotel's outdoor dining area.

"Nice restaurant!"

CA $298 total

includes taxes & fees

Aug 30 - Aug 31

Relax by the serene pool, surrounded by palm trees and a well-lit lounge area.

"Everything real nice clean and perfect stay"

CA $231 total

includes taxes & fees

Sep 2 - Sep 3

Check in and unwind in our stylish lobby, featuring a digital kiosk and comfortable seating areas.

"Great location and clean, comfortable hotel. "

CA $143 total

includes taxes & fees

Aug 24 - Aug 25

Welcome to our hotel, featuring a striking entrance with a covered walkway leading to the main building.

"Great hotel!"

CA $153 total

includes taxes & fees

Aug 22 - Aug 23

Relax in the hotel's spacious lobby, featuring a reception desk, seating areas with sofas and armchairs, and a coffee table.

"On a roadtrip, only stayed one night. Staff was very welcoming and polite. The area is super convenient gas stations, shops and food. The breakfast choices were excellent. They are remodeling but no one was working while we were there. We would definitely visit again."

CA $156 total

includes taxes & fees

Aug 24 - Aug 25

Enjoy meals with a view of the ocean from this dining area with large windows and a bar.

"Great pool and they kept the beach clean "

Relax by the serene pool surrounded by lush greenery and shaded by a pergola.

"Nice hotel, staff friendly."

CA $162 total

includes taxes & fees

Sep 7 - Sep 8

Hotel Desoto features a symmetrical facade with a large entrance and well-manicured grounds.

"Great property for the price."

CA $115 total

includes taxes & fees

Aug 11 - Aug 12

Save an average of 15% on thousands of hotels when you're signed in

Top Mississippi Hotel Reviews

Hard Rock Hotel & Casino Biloxi

10/10 Excellent

"This trip was good. My only complaint was that on Saturday housekeeping never came to clean my room or give me fresh towels. I did get them when I called and asked for them "

Palace Casino Resort

10/10 Excellent

"1. Casino to rooms very clean 2. Friendly staff from check in, cafe, dining to spa 3. Service was stellar 4. Dined at Cafe, Stacked & Mignon (all excellent) 5. Zero Smoke - love it 6. Gift Shop was fun! 7. Shout out to the Tiffany's @ Pure Spa (massage & facial), Dallas for excellent service @ Mignon's. We will be BACK! 10+ Stars!!!"