Title: Book the Best Oxford SPA Resorts from CA $110 - Spa Hotels in Oxford, MS | Expedia.ca [Hotels in Oxford](https://expedia.ca/Oxford-Hotels.d6058680.Travel-Guide-Hotels)[Vacation Rentals in Oxford](https://expedia.ca/Oxford-Vacation-Rentals.d6058680.Travel-Guide-VacationRentals)[Flights to Oxford](https://expedia.ca/Cheap-Flights-To-Oxford.d6058680.Travel-Guide-Flights)[Oxford Car Rentals](https://expedia.ca/Car-Rentals-In-Oxford.d6058680.Car-Rental-Guide)[Oxford Vacation Packages](https://expedia.ca/Oxford.d6058680.Destination-Travel-Guides) ![Oxford Downtown in Mississippi](https://images.trvl-media.com/place/6058680/ee53cad1-4a60-4af1-8b73-da3add1487f1.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Oxford, MS from CA $110 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Oxford Spa Hotels Tonight [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=6058680&startDate=2025-12-11&endDate=2025-12-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=6058680&startDate=2025-12-12&endDate=2025-12-13&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6058680&startDate=2025-12-12&endDate=2025-12-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6058680&startDate=2025-12-19&endDate=2025-12-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Oxford ![Exterior](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/46d9ec38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/cef987ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/ef67498d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/40000000/39580000/39577100/39577074/8c5783f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Oxford [](https://www.expedia.ca/Oxford-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oxford.h39577074.Hotel-Information) Oxford 9.2/10 Wonderful (917) "Nice place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hilary CA $109 CA $119 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Oxford-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Oxford.h39577074.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/460000/456100/456093/86795d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/456100/456093/e6715d5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/460000/456100/456093/a07301af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/460000/456100/456093/3deb9a89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Oxford by IHG [](https://www.expedia.ca/Oxford-Hotels-Holiday-Inn-Express-Hotel-Suites-Oxford.h456093.Hotel-Information) Oxford 8.6/10 Excellent (659) "friendly staff, safe, clean, and close to downtown " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emery CA $101 CA $110 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Oxford-Hotels-Holiday-Inn-Express-Hotel-Suites-Oxford.h456093.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/19000000/18570000/18566700/18566641/44c116b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/19000000/18570000/18566700/18566641/bb2d29d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18570000/18566700/18566641/2a4bb8fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18570000/18566700/18566641/aa5dbb0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Oxford [](https://www.expedia.ca/Oxford-Hotels-Home2-Suites-By-Hilton-Oxford.h18566641.Hotel-Information) Oxford 9.2/10 Wonderful (636) "Yes would stay again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenn CA $123 CA $134 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Oxford-Hotels-Home2-Suites-By-Hilton-Oxford.h18566641.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/35000000/34300000/34293200/34293185/a16fa507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/35000000/34300000/34293200/34293185/facec16a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/35000000/34300000/34293200/34293185/d4d9d45e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/35000000/34300000/34293200/34293185/910770b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Oxford [](https://www.expedia.ca/Oxford-Hotels-Tru-By-Hilton-Oxford.h34293185.Hotel-Information) Oxford 9.2/10 Wonderful (874) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenola CA $112 CA $122 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Oxford-Hotels-Tru-By-Hilton-Oxford.h34293185.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4550000/4542300/4542273/0f429fbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4550000/4542300/4542273/5236dc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4550000/4542300/4542273/5a8e98e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/5000000/4550000/4542300/4542273/d65cffa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Oxford/Conference Center [](https://www.expedia.ca/Oxford-Hotels-Hampton-Inn-OxfordConference-Center.h4542273.Hotel-Information) Oxford 9.2/10 Wonderful (488) "The hotel was very clean, had comfortable beds, and offered a great breakfast. The staff was helpful and friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole CA $115 CA $125 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Oxford-Hotels-Hampton-Inn-OxfordConference-Center.h4542273.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12900000/12894500/12894458/45389fa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/13000000/12900000/12894500/12894458/98006e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12900000/12894500/12894458/0063badc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/13000000/12900000/12894500/12894458/a71bd8b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Oliver Hotel, Oxford [](https://www.expedia.ca/Oxford-Hotels-Chancellors-House.h12894458.Hotel-Information) Courthouse Square Historic District 9.6/10 Exceptional (320) "Have stayed here many times and always a great experience. Rooms are very comfortable and staff is extremely helpful. Only place we stay when visiting our daughter at Ole Miss." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly Elizabeth CA $185 CA $202 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Oxford-Hotels-Chancellors-House.h12894458.Hotel-Information) ![2 restaurants, breakfast, dinner served; American cuisine](https://images.trvl-media.com/lodging/13000000/12890000/12880100/12880011/9be878fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/13000000/12890000/12880100/12880011/3dd2aed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/13000000/12890000/12880100/12880011/c7df05bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12890000/12880100/12880011/a1bfafc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Oxford [](https://www.expedia.ca/Oxford-Hotels-Courtyard-By-Marriott-Oxford.h12880011.Hotel-Information) Oxford 8.4/10 Very good (526) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $131 CA $143 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Oxford-Hotels-Courtyard-By-Marriott-Oxford.h12880011.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8130000/8125100/8125012/83664db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed | Living area](https://images.trvl-media.com/lodging/9000000/8130000/8125100/8125012/654195d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/9000000/8130000/8125100/8125012/92b69db8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8130000/8125100/8125012/9d02a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites Oxford [](https://www.expedia.ca/Oxford-Hotels-TownePlace-Suites-Oxford.h8125012.Hotel-Information) Oxford 9.2/10 Wonderful (466) "Good location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Harry CA $148 CA $161 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Oxford-Hotels-TownePlace-Suites-Oxford.h8125012.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/16600/16565/c6bcd6ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/20000/16600/16565/14db7d63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/20000/16600/16565/ec19e982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16600/16565/67e3f07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Graduate by Hilton Oxford [](https://www.expedia.ca/Oxford-Hotels-Graduate-Oxford.h16565.Hotel-Information) Courthouse Square Historic District 9.0/10 Wonderful (1000) "Good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emma CA $157 CA $171 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Oxford-Hotels-Graduate-Oxford.h16565.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/108000000/107990000/107985900/107985884/984f4d73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/108000000/107990000/107985900/107985884/042343d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107990000/107985900/107985884/2148e674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107990000/107985900/107985884/fea015b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The West Palm, 2BR Oasis by Velvet Ditch Villas [](https://www.expedia.ca/Oxford-Hotels-West-PalmDouble-DeckerOn-The-Square.h107985884.Hotel-Information) Courthouse Square Historic District 10/10 Exceptional (2) "Location was excellent to Square " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa S. CA $177 CA $452 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Oxford-Hotels-West-PalmDouble-DeckerOn-The-Square.h107985884.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-25&endDate=2025-12-26®ionId=6058680&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Oxford ### Top Oxford attractions for a relaxing vacation For travellers seeking relaxation blended with a touch of Southern charm, Oxford, Mississippi offers a delightful array of attractions to complement a stay in a hotel with a spa. Begin your exploration at the University of Mississippi campus, where the stunning architecture and serene grounds provide a perfect backdrop for a leisurely stroll. Next, immerse yourself in local history at the Rowan Oak, the former home of legendary author William Faulkner, where you can wander through the gardens and gain insights into the literary great's life. For art enthusiasts, the University Museum showcases a diverse collection, including works by local artists, making it an inspiring stop. After a day of culture, unwind at the picturesque Lake Sardis, where you can enjoy nature trails and perhaps a peaceful afternoon picnic. Finally, end your day by indulging in a little retail therapy at the charming boutiques on the historic Oxford Square. Staying in the heart of Oxford not only places you close to these attractions but also offers easy access to boutique hotels that feature luxurious spa services, ensuring that your experience is both rejuvenating and memorable. Enjoy personalised service and exquisite amenities, making every moment of your stay a pleasure. ## Top Oxford Hotel Reviews ![Super 8 by Wyndham Oxford](https://images.trvl-media.com/lodging/1000000/800000/790600/790514/140f3c7e_y.jpg) ### Super 8 by Wyndham Oxford 10/10 Excellent "Good" [](https://expedia.ca/Oxford-Hotels-Super-8-By-Wyndham-Oxford.h790514.Hotel-Information) ![Hampton Inn Oxford-West](https://images.trvl-media.com/lodging/1000000/970000/967400/967340/ac5b6370_y.jpg) ### Hampton Inn Oxford-West 10/10 Excellent "Very nice place " [](https://expedia.ca/Oxford-Hotels-Hampton-Inn-Oxford-West.h967340.Hotel-Information) ![TownePlace Suites Oxford](https://images.trvl-media.com/lodging/9000000/8130000/8125100/8125012/83664db9_y.jpg) ### TownePlace Suites Oxford 10/10 Excellent "Love this clean hotel" [](https://expedia.ca/Oxford-Hotels-TownePlace-Suites-Oxford.h8125012.Hotel-Information) ## Frequently asked questions ### How much does a spa hotel in Oxford cost? ### Is it cheaper to book a spa hotel in Oxford with flights as part of a package deal? ### Are there any unique spa experiences available in Oxford? > Delta Phoenix Medical Spa is a modern medspa specialising in advanced anti-ageing treatments such as Botox, fillers, PRP/PRF, PDO threads, and hormone and peptide therapies. They focus on natural, refined results and comprehensive wellness, including IV hydration and medical weight loss, with personalised treatment plans tailored to individual needs. > > > Renew Med Spa at Dermatology Associates of Oxford blends advanced beauty treatments with relaxation, offering Botox, fillers, spray tans, rejuvenating facials, lash extensions, brow tinting and lamination, and premium skincare products. Their facials are customised for hydration, exfoliation, and anti-ageing, providing a luxurious and personalised experience. > > > La Rousse Salon & Spa combines high-quality product lines with warm Southern hospitality, offering a unique salon and spa experience just north of the Oxford square. > > > Southern Chic' Salon & Spa, located in West Oxford, offers a luxury experience with services including haircuts, custom hair colouring, full-body waxing, and spa treatments delivered by highly skilled professionals. > > > SKIN Oxford is a facial spa offering medical-grade facials, microneedling, laser treatments, and non-surgical cosmetic injections designed to improve skin health and appearance with advanced techniques. ### How can I save on a spa hotel in Oxford with Expedia? ### Can I cancel my spa hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [4 Star Hotels in Burney Branch ](https://www.expedia.ca/4Star-Burney-Branch-Oxford-Hotels.s40-n553248635976471494-0.Travel-Guide-Filter-Hotels) - 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