Title: Defiance Motel: Browse Cheap Motels in Defiance 2026 | Expedia.ca [Hotels in Defiance](https://expedia.ca/Defiance-Hotels.d6353634.Travel-Guide-Hotels)[Vacation Rentals in Defiance](https://expedia.ca/Defiance-Vacation-Rentals.d6353634.Travel-Guide-VacationRentals)[Flights to Defiance](https://expedia.ca/Cheap-Flights-To-Defiance.d6353634.Travel-Guide-Flights)[Defiance Car Rentals](https://expedia.ca/Car-Rentals-In-Defiance.d6353634.Car-Rental-Guide)[Defiance Vacation Packages](https://expedia.ca/Defiance.d6353634.Destination-Travel-Guides) ![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-02-06&endDate=2026-02-08&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-02-13&endDate=2026-02-15&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-02-27&endDate=2026-03-01&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-03-27&endDate=2026-03-29&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDefiance-Motels.d6353634-aaMotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDefiance-Motels.d6353634-aaMotels.Travel-Guide-Accommodation) ## Top Defiance Hotel Reviews ![Drury Plaza Hotel St. Louis St. Charles](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/7efb516b_y.jpg) ### Drury Plaza Hotel St. Louis St. Charles 10/10 Excellent "Staff were very helpful" [](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information) ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg) ### Ameristar Casino Resort and Spa 10/10 Excellent "Spotless room" [](https://expedia.ca/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Crowne Plaza St. Louis Airport by IHG](https://images.trvl-media.com/lodging/1000000/10000/3100/3010/45ba14e8_y.jpg) ### Crowne Plaza St. Louis Airport by IHG 10/10 Excellent "Clean room friendly staff great room" [](https://expedia.ca/St-Louis-Hotels-Crowne-Plaza-St-Louis-Airport.h3010.Hotel-Information) ![Drury Plaza Hotel St. Louis Chesterfield](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/c1fcfc39_y.jpg) ### Drury Plaza Hotel St. Louis Chesterfield 10/10 Excellent "After many years of travelling hotel chains for kids hockey, this was my first time at a Drury hotel. By far the best travel hotel we have stayed at; rooms are large and clean, staff exceptional polite, excellent hot breakfast. What I was really amazed with was their daily happy hour; food is like a meal with many options plus 3 drink tickets per person per day; great value for sure 👍; very impressed " [](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/ad47a940_y.jpg) ### Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West 10/10 Excellent "No complaints " [](https://expedia.ca/St-Louis-Hotels-Larkspur-Landing-Extended-Stay-Suites-St-Louis-Riverport-Airport-West.h1658956.Hotel-Information) ![Sleep Inn & Suites O'Fallon MO - Technology Drive](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/133d5cf7_y.jpg) ### Sleep Inn & Suites O'Fallon MO - Technology Drive 10/10 Excellent "A very nice one night stay on our roadtrip! The staff are very friendly and available, the place was clean, quiet and safe and the breakfast was fresh and hot. Would definitely stay here again. " [](https://expedia.ca/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information) ![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/529fe0ff_y.jpg) ### Country Inn & Suites by Radisson, St. Charles Historic District 10/10 Excellent "Kay was great and helped us find places to go out and the rooms are nice and clean " [](https://expedia.ca/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ![Hollywood Casino & Hotel St. Louis](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg) ### Hollywood Casino & Hotel St. Louis 10/10 Excellent "Room was excellent. Staff were happy and friendly. Final Cut steakhouse was very good. " [](https://expedia.ca/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) ![Hampton Inn St. Charles St. Peters](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/8c366380_y.jpg) ### Hampton Inn St. Charles St. Peters 10/10 Excellent "Quick checkin - clean room" [](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information) ## Find out more about Defiance ## Defiance Motels information | Number of reviews | 3,638 | | ----------------- | -------- | | Accommodation | 9 Motels | | Lowest Price | CA $84 | | Highest Price | CA $116 | ## Frequently asked questions ### What can I expect from a motel trip to Defiance? ### What is a motel? ### What are the best motels in Defiance? ### What can I do in Defiance? ### What's the weather like in Defiance? ### What are my options for getting around Defiance when staying in a motel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - 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