
De Soto Vacation Packages
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Your De Soto Vacation
Experience the unique character and personality of De Soto with a tailor-made De Soto vacation package. From its welcoming locals to its rich history, you'll never have a boring moment in this city. A trip to De Soto wouldn't be complete without visiting a few top attractions, starting with Victoria Glaces Conservation Area Trailhead. No matter your travel plans or budget, organizing a tailored De Soto vacation is a cinch with Expedia.
Top De Soto Vacation Deals
Price found within the past 48 hours. Click for updated prices.

White House at Grand Central
Grand Center
Price was CA $1,271, price is now CA $1,170 per person
CA $1,170
per person
Aug 21 - Aug 28
found 16 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8.4/10 Very good! (138 reviews)
We liked the location of this hotel—it's right on campus or just across the street, making it feel safe and convenient. You’re only a couple of blocks away from fast food, Walgreens, and the bus, which was so convenient. The area feels regal and historic with beautifully manicured lawns, and everything was just as pictured. The air conditioning worked well, all the amenities were in place, and we really enjoyed the old-timey charm.
The only minor suggestion I have is about the check-in process. Instead of having to haul luggage to a sister hotel to provide a credit card, it would be great to handle that by phone. It would save that extra trip, especially in the heat. Otherwise, it was a wonderful stay!
Reviewed on Jun 29, 2026

Tru By Hilton St. Louis Downtown
Downtown West
Price was CA $1,364, price is now CA $1,194 per person
CA $1,194
per person
Aug 21 - Aug 28
found 16 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
7.6/10 Good! (805 reviews)
Staff were incredibly helpful and very polite. Every staff member we encountered was positive and doing a great job. We had a few issues like the blinds in our room not opening and a hook that needed to be repaired, but we only stayed for a short period so it wasn’t a huge deal. We utilized the valet parking and we were very happy with that decision. The location was ideal for walking to the stadium and city museum. The breakfast options changed both morning we were there which was great.
Reviewed on Jun 29, 2026

Aloft by Marriott St. Louis Cortex
Central West End
Price was CA $1,431, price is now CA $1,274 per person
CA $1,274
per person
Aug 21 - Aug 28
found 16 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8.6/10 Excellent! (947 reviews)
Friendly staff but I was surprised there was not self-parking onsite
Reviewed on Jun 30, 2026

Best Western Plus St. Louis West-Westport
Westport
Price was CA $1,297, price is now CA $1,177 per person
CA $1,177
per person
Aug 21 - Aug 28
found 16 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8/10 Very good! (1,091 reviews)
Loved the location. Obvious that it is being renovated. Beautiful bathroom. Nice breakfast area. Easy parking.
Reviewed on Jun 28, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
Price was CA $1,356, price is now CA $1,232 per person
CA $1,232
per person
Aug 21 - Aug 28
found 16 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8.8/10 Excellent! (1,309 reviews)
The room was clean and well maintained. The staff were good. I loved the bathroom it provided plenty of space. We had a few hiccups with the valet, but they fixed it immediately. Overall, a great stay.
Reviewed on Jun 30, 2026
De Soto Hotel Deals

Gated 35-Acre De Soto Estate: Pool, Lake & Patio!
De Soto MO
10/10 Exceptional! (4 reviews)
"The home is spacious and superb for large groups with plenty of variety of options for things to do. We stayed in December and as such didn’t use the pool. We would come again, anytime! The host was helpful with addressing our questions and needs."
Reviewed on Dec 28, 2025

Secluded cabin on private property
De Soto MO
10/10 Exceptional! (72 reviews)
"Great place for a small family. We plan on staying again"
Reviewed on Jun 21, 2026

Rustic Cabin Escape for Group Glamping Vacations in De Soto, Missouri
De Soto MO
10/10 Exceptional! (1 review)
"It was an excellent stay and we plan to so it again! I have one suggestion, add steps to the right side of the front porch."
Reviewed on Jun 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.







