Colleton County Vacation Home Rentals from CA $120: Search Top Private Vacation Homes for Rent

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Top cities in Colleton County

The exterior of the Colleton County Courthouse at 101 Hampton Street, established in 1822.

Find vacation rentals that suit your style

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Our top choices for Colleton County vacation homes

A house with a well-lit porch and a grassy lawn.

1. Cottage: 3005 Palmetto Blvd.

Edisto Beach

Linda C.

A wooden deck with wicker furniture overlooking a beach.

2. Oceanfront Showplace - Island Manor

Edisto Beach

John B.

A dining area with a wooden table and chairs, a painting on the wall, and a view through a window.

3. Relax on Huge Porch Overlooking Marsh- Short Walk to Beach

Edisto Beach

Cindy M.

CA $477 total

includes taxes & fees

Nov 16 - Nov 17

A room with large windows, wooden walls, and a small table.

4. 2nd Row on Point St.,NO PAVED RD TO CROSS! 4Br/3bth OCEANVIEWS, Linens Included!

Edisto Beach

Cynthia G.

A wooden deck with a view of the ocean, a covered seating area with chairs, and a white railing.

5. The Sandy Pineapple! Direct Edisto Beach oceanfront with 4 bedrooms and 2 baths

Edisto Beach

Greg G.

A deck with white railings overlooking a golf course and a pond.

6. Private 4 bedroom home near beach and on golf course

Edisto Beach

Deirdre C.

A wooden deck with a table and chairs, overlooking a body of water and a distant pier.

7. A Little Piece of Heaven on Big Bay Creek

Edisto Beach

"This is truly a special place! You can’t beat the location, especially if you have a boat. The house was equipped with everything my family needed for the week. We enjoyed fishing and crabbing off of the dock. We appreciated the shade from the covered portion of the dock and the fresh water hose to clean our boat off. We thoroughly appreciated the peace and quiet. Joan was a helpful and responsive host and we hardly knew she and her husband were even there during our stay."

Jillian V.

A modern building with a covered patio area, surrounded by a well-maintained lawn and trees.

8. Egret Cottage Suite 3715-B

WALTERBORO

Vonda J.

CA $366 total

includes taxes & fees

Dec 8 - Dec 9

A modern living room with a sofa, coffee table, and a dining area with chairs.

9. The Salty Monkey

Edisto Beach

Marsha S.

A spacious living room with a sofa, armchairs, a coffee table, a TV, and a ceiling fan.

10. OCEANFRONT 4 Bedroom 2 Bath Beach House

Edisto Beach

Diane S.

View all properties

Top reviews in Colleton County

A modern conference room with a large table, multiple chairs, and a chessboard.

Holiday Inn Exp Walterboro by IHG

Walterboro

10/10 Excellent

Claude

A hotel room with two beds, a chair, a desk, and a mirror.

Econo Lodge Walterboro I-95

Walterboro

10/10 Excellent

Kenneth

A hotel room with a bed, a desk with a computer, a television, and a microwave.

Red Roof Inn Walterboro

Walterboro

10/10 Excellent

RJay

A hotel room with a bed, bedside tables, a desk, a TV, a window, and a door.

Southern Inn By OYO Walterboro I-95

Walterboro

8/10 Good

Darren

A balcony with wicker chairs and a table, surrounded by columns and a brick wall.

607 Bay Inn Downtown Beaufort

Historic District

10/10 Excellent

This beautifully restored property is in the heart of downtown Beaufort with great views of the water. The staff is welcoming and dedicated to making your stay a great experience. The common area includes a full kitchen and shaded sitting on two front porches. The parking is ample and conveniently located behind the building with an additional entrance. Overall, this is a great way to explore and enjoy Beaufort.

Richard