A marina with numerous boats docked in a circular arrangement, surrounded by a coastal landscape and a clear blue sky.

Best 5 Star Hotels in Santorini CA $222

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Check availability on Santorini 5 Star Hotels

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Sep 13 - Sep 14
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Sep 14 - Sep 15
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Sep 18 - Sep 20
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Sep 25 - Sep 27

Our top choices for Santorini 5-star hotels

A dining area with a table set for two, overlooking a pool with a modern architectural backdrop.
A modern bathroom with a marble vanity, wooden paneling, and a large mirror.
A modern hotel room with a large bed, a desk, and a view of the sea.
A modern room with a stone wall, a dining area with a table and chairs, and a view of the ocean.

1. Cresanto Luxury Suites

Cresanto Luxury Suites
Santorini
United States
Aran
CA $313
CA $380 total
includes taxes & fees
Oct 11 - Oct 12
Cresanto Luxury Suites
A modern building with large windows, an infinity pool, and a clear blue sky.
A modern bedroom with a large window, a bed, a bedside table, and a view of a desert landscape.
An outdoor dining area with tables and chairs, a pool, and umbrellas.
A pathway leading through a landscaped garden with various plants and a mountain in the background.

2. NOŪS Santorini

NOŪS Santorini
Santorini
United Kingdom
Jessica
CA $353
CA $425 total
includes taxes & fees
Oct 14 - Oct 15
NOŪS Santorini
A modern living room with a sofa, a coffee table, and a view of the ocean.
A resort pool with a central island, sun loungers, and a view of the ocean.
A spacious room with a wooden dining table, chairs, a hammock, and a wall-mounted shelf with plants.

3. Andronis Arcadia Hotel

Andronis Arcadia Hotel
Santorini
Canada
Alexandre
CA $888
CA $1,033 total
includes taxes & fees
Oct 10 - Oct 11
Andronis Arcadia Hotel
A view from a bathtub to a sunset over water, with a clear sky and distant land.
A spa treatment area with a person receiving a massage, a candle, and a glass of drink on a balcony overlooking a coastal view.
A serene spa setting with a massage table under a canopy, overlooking a scenic ocean view at sunset.
A balcony with a white interior, a wooden chair, and a view of the sea and distant land.

4. Volcano View Hotel Santorini

Volcano View Hotel Santorini
Santorini
United Kingdom
Ahmetali
CA $320
CA $387 total
includes taxes & fees
Oct 12 - Oct 13
Volcano View Hotel Santorini
A pool area with lounge chairs, a bar, and a stone wall.
A modern hotel room with a bed, a desk, a chair, and a view of the sea.
A beach walkway with thatched umbrellas and lounge chairs.
A breakfast table with various food items and drinks, overlooking a beach with umbrellas and lounge chairs.

5. Costa Grand Resort & Spa

Costa Grand Resort & Spa
Santorini
United Kingdom
Luke Jonathan
CA $190
CA $239 total
includes taxes & fees
Oct 11 - Oct 12
Costa Grand Resort & Spa
A poolside area with lounge chairs and umbrellas, overlooking a clear blue sea.
A hotel room with a balcony, a sofa, a small table with glasses and a plate, and a chair.
A bedroom with a bed, a desk, and a view of the sea.
A coastal building with white domed roofs overlooking the sea.

6. Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas
Santorini
United States
Jorge
CA $457
CA $544 total
includes taxes & fees
Oct 11 - Oct 12
Santo Pure Oia Suites & Villas
A modern indoor pool area with a view of a mountain and buildings in the background.
A modern bedroom with a bed, TV, and a view of a pool.
A rooftop terrace with a table set for dining, lounge chairs, and a view of the cityscape.
A modern lobby with a reception desk, a grey sofa, a coffee table, and a chandelier.

7. Antoperla Luxury Hotel & Spa

Antoperla Luxury Hotel & Spa
Santorini
Canada
Marius Calin
CA $278
CA $339 total
includes taxes & fees
Sep 16 - Sep 17
Antoperla Luxury Hotel & Spa
A poolside area with lounge chairs and umbrellas, a waiter serving a drink to a seated woman.
A modern living room with a sofa, round coffee table, and armchair, a floor lamp, and a view through a large window.
A modern restaurant with a bar area, marble flooring, and a variety of seating options including tables and chairs.
A modern hotel entrance with a geometric floor design, a palm tree, and a woman in a dress.

8. De Sol Spa Hotel

De Sol Spa Hotel
Santorini
United Kingdom
Chi
CA $243
CA $300 total
includes taxes & fees
Oct 14 - Oct 15
De Sol Spa Hotel
A modern hotel with a pool, outdoor seating, and a view of the city at dusk.
A modern hotel with a flat roof, large windows, and a balcony.
An outdoor dining area with tables set for breakfast, surrounded by lush greenery and vibrant pink flowers.

9. The Majestic Hotel

The Majestic Hotel
Santorini
Canada
Anthony
CA $229
CA $284 total
includes taxes & fees
Oct 12 - Oct 13
The Majestic Hotel
A person relaxing in a infinity pool with a view of the sea and distant islands.
A couple dancing in an outdoor setting with a view of the sea and hills.
A terrace with a view of the sea, white chairs, and potted plants.
A bedroom with a bed, a seating area with a view, and a balcony with a table and chairs.

10. Pegasus Spa Hotel

Pegasus Spa Hotel
Santorini
United States
Fahima
CA $436
CA $519 total
includes taxes & fees
Sep 14 - Sep 15
Pegasus Spa Hotel
A woman in a bikini standing in a pool with a view of a mountainous landscape and a clear sky.
A person sitting on a balcony overlooking a coastal view with thatched umbrellas.
A coastal hotel with a stone pathway leading to a welcoming entrance, surrounded by Mediterranean-style buildings and a mountainous backdrop.
A modern living room with a large arched window, a fireplace, and a cozy seating area.

11. Santorini Princess Spa Hotel

Santorini Princess Spa Hotel
Santorini
Canada
Simon
CA $200
CA $251 total
includes taxes & fees
Sep 14 - Sep 15
Santorini Princess Spa Hotel
A rooftop terrace with a hot tub, lounge chairs, and a view of the sea.
A modern building with a curved roof overlooking a coastal landscape.
A modern hotel room with a large window, a curved desk, a chair, a flat-screen TV, and a view of the coastline.
A dimly lit room with a large bathtub, two wooden chairs, and a small round table.

12. Andronis Concept

Andronis Concept
Santorini
United States
William
CA $976
CA $1,133 total
includes taxes & fees
Oct 10 - Oct 11
Andronis Concept
A modern outdoor lounge area with a pool, stone walls, and seating arrangements.
A bedroom with a large window overlooking a pool and ocean.
A sunlit outdoor seating area with stone walls and a view of the sea.
A bedroom with a large window overlooking the sea, a balcony with seating, and a bed with a view.

13. Canaves Epitome - Small Luxury Hotels of the World

Canaves Epitome - Small Luxury Hotels of the World
Santorini
United States
Izabella
CA $1,063
CA $1,231 total
includes taxes & fees
Oct 9 - Oct 10
Canaves Epitome - Small Luxury Hotels of the World
A serene infinity pool with a row of outdoor seating and umbrellas.
A room with a stone wall, a large abstract metal sculpture, and a modern sofa with cushions.
An outdoor dining area with a curved bench and table, overlooking a coastal landscape.
A dining area with a table set for two, featuring a modern design with potted plants and a decorative wall piece.

14. Magma Resort Santorini, Part of The Unbound Collection By Hyatt

Magma Resort Santorini, Part of The Unbound Collection By Hyatt
Santorini
United Kingdom
Akash
CA $446
CA $530 total
includes taxes & fees
Oct 1 - Oct 2
Magma Resort Santorini, Part of The Unbound Collection By Hyatt
A modern outdoor terrace with a pool, two lounge chairs, and a view of the sea and distant cliffs.
A modern hotel room with a large bed, a balcony with a view of the sea, and a dining area.
A view from a balcony with a stone bathtub, overlooking a coastal town with white buildings and boats on the water.
A room with a view of a body of water, a dining area with chairs, a sofa, and a wooden cabinet.

15. Andronis Luxury Suites

Andronis Luxury Suites
Santorini
United States
Nicholas
CA $1,532
CA $1,764 total
includes taxes & fees
Oct 11 - Oct 12
Andronis Luxury Suites
A luxurious bedroom with a large sliding glass door leading to a private balcony overlooking a scenic ocean view.
A modern building with arched openings revealing a well-lit interior with seating and a rock formation.
A woman in a swimsuit standing in a clear pool with a view of the sea and distant land.
A room with a view of the sea, a dining table with a bottle of wine, and a sofa.

16. One of One Hotel

One of One Hotel
Santorini
Canada
Amanda
CA $700
CA $819 total
includes taxes & fees
Oct 14 - Oct 15
One of One Hotel
A pool area with white walls, palm trees, and lounge chairs.
A courtyard with a central palm tree, stone pathways, and white buildings with blue accents in the background.
A modern bedroom with a large bed, a seating area, a small table with drinks, and a view of mountains through an open door.
A person walking along a rocky beach with a mountainous backdrop.

17. Santorini Kastelli Resort

Santorini Kastelli Resort
Santorini
United States
Amanda
CA $235
CA $291 total
includes taxes & fees
Oct 14 - Oct 15
Santorini Kastelli Resort
An infinity pool with a view of the sea and distant islands.
A room with a view of a mountainous coastline, a potted orchid, a book on the table, and two chairs.
A balcony with a table, a chair, and a white umbrella overlooking a coastal view with a boat on the water and buildings on the cliff.
A spacious room with a large window offering a view of the sea and mountains. There is a dining table with chairs, a white sofa, and a wooden cabinet.

18. Katikies Santorini – Pelagos House - The Leading Hotels of the World

Katikies Santorini – Pelagos House - The Leading Hotels of the World
Santorini
United States
yoon
CA $951
CA $1,105 total
includes taxes & fees
Oct 10 - Oct 11
Katikies Santorini – Pelagos House - The Leading Hotels of the World
A woman relaxing in a clear infinity pool with a view of a mountainous coastline.
A room with a view of the sea, a door leading outside, a sofa with pillows, and a potted plant.
A modern, white interior with a curved ceiling, a sofa, a small table, and a view of the outdoors.
A hot tub with a view of a coastal town at sunset.

19. Art Maisons Aspaki Exclusive Suites

Art Maisons Aspaki Exclusive Suites
Santorini
United States
John
CA $1,076
CA $1,246 total
includes taxes & fees
Oct 4 - Oct 5
Art Maisons Aspaki Exclusive Suites
A pool with lounge chairs and a view of a mountainous landscape.
A courtyard with tables and chairs, a fountain, and palm trees.
A modern bedroom with a bed, a desk, and a chair. There is a window with curtains and a view of the outdoors.
A courtyard with tables and chairs, palm trees, and a blue dome in the background.

20. Katikies Garden Santorini - The Leading Hotels Of The World

Katikies Garden Santorini - The Leading Hotels Of The World
Santorini
United States
Nicholas
CA $449
CA $534 total
includes taxes & fees
Oct 13 - Oct 14
Katikies Garden Santorini - The Leading Hotels Of The World
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santorini.
Santorini Palace

Santorini Palace

Fira town Santorini Santorini Island
CA $182
CA $222 total
Sep 29 - Sep 30
includes taxes & fees
9/10 Wonderful! (820 reviews)
Santorini Palace
Hotel Daedalus

Hotel Daedalus

Fira Town Santorini Santorini Island
CA $200
CA $243 total
Oct 2 - Oct 3
includes taxes & fees
8.8/10 Excellent! (186 reviews)
Hotel Daedalus
El Greco Resort

El Greco Resort

Fira Santorini Santorini Island
CA $188
CA $229 total
Oct 1 - Oct 2
includes taxes & fees
9.2/10 Wonderful! (596 reviews)
El Greco Resort
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santorini

Those white-washed villages perched on volcanic cliffs offer the most spectacular sunset views over the caldera. Spend mornings exploring ancient Akrotiri ruins, then cool off at red and black sand beaches before enjoying local wine at hillside tavernas.

See all hotels in Santorini
A coastal town with white buildings and blue domes, a rocky coastline, and boats in the water.

Top Santorini Hotel Reviews

Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

10/10 Excellent
"Beautiful property and friendly employees. The pools are clean and the spa is great as well. Only recommendation is improvement on the turndown service"
kristy 3-night trip
Posted 3 hours ago
Santo Pure Oia Suites & Villas
NOŪS Santorini

NOŪS Santorini

8/10 Good
"Pros - staff were great, so friendly & helpful, pool is amazing - we had a pool in our room which was great and perfect temp. Room size is really generous & spacious for the Eurphoria suite. Gym is one of the best hotel gyms . Spa is beautiful & really enjoyable experience, the messages are great. Water all round hotel, fruit at breakfast, toiletries quality of body wash/ shampoo etc was excellent. coffee machine in room with a big fridge, Towels were always stocked. They have an app which is great and staff super responsive on WhatsApp, pool food was good too! Cons - a few areas where the hotel let itself down and to be a true 5 star I think it needs to be better at certain areas, firstly, there should be speakers in the room, although room was big it was lacking , the hotel did also not replace the vanity kits which was very frustrating, I believe there should be a free shuttle into Fira, instead taxis are really expensive and the hotel use a 3rd party company that charge more than local taxis. The coffee at breakfast was terrible, there was only a limited choice of different eggs. For a 5 star hotel it should not be machine coffee and should cater for omelettes, fried , poached etc. there was constant rubbish left around the bins not collected which is not pleasant. Parts of the hotel were “closed for renovation” - restaurant/ vitamin bar/gift shop. This felt like a cover up for not opening due to quieter times which is quite misleading & we observed no construction"
Melissa 7-night trip
Posted 6 days ago
NOŪS Santorini

Find out more about Santorini

Five Star Hotels in Santorini

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Santorini so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Santorini and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Santorini

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to Santorini

The results are in, and Santorini 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Santorini! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Santorini today and settle down in the lap of luxury tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Santorini?
You'll find a variety of pricing options for a 5-star hotel in Santorini on Expedia. The amount you pay will depend on your travel dates, length of stay and other factors. Compare available properties for your desired dates and use our pricing and other filters to find the perfect high-end stay.
  • Search for the lowest price per night from CA $222
What makes a hotel 5 stars in Santorini?
Faultless guest service is the foundation of every 5-star hotel in Santorini. From the minute you arrive, staff attend to your every whim, whether arranging valet parking or providing in-room beauty treatments. In addition, hotels must feature upscale amenities to be considered for a 5-star rating. These can include luxury bathrobes, saunas or spas, swimming pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Santorini?
Expedia's filters are the quickest way to search for exactly what you want. Select "5-star" and "All inclusive" to see the most upscale hotels in Santorini where your meals, room, activities and entertainment are included in the upfront price. At these retreats, your trip is pure relaxation and indulgence from the moment you step foot in the lobby.

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