A beach with a wooden pavilion, clear blue sky, and dense green foliage.

5 Stars Hotels in Lower Matecumbe Key, Islamorada from CA $337

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Check availability on Lower Matecumbe Key 5 Star Hotels

Tonight
Oct 6 - Oct 7
Tomorrow
Oct 7 - Oct 8
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Lower Matecumbe Key 5-star hotels

A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.

1. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
United States
RAIBEL
CA $226
CA $359 total
includes taxes & fees
Oct 20 - Oct 21
Cheeca Lodge & Spa
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.
A gated entrance to a resort with palm trees and a clear sky.

2. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
United States
Christian
CA $618
CA $786 total
includes taxes & fees
Oct 14 - Oct 15
The Islands of Islamorada
A resort pool with a view of the sea, surrounded by palm trees and lounge chairs.
A modern white building with a garage, surrounded by palm trees and a clear blue sky.
A wooden deck with a spiral staircase leading to an upper level.
A clean, empty garage with fluorescent lighting, a metal garage door, and visible plumbing on the ceiling.

3. Sea Glass Cove

Sea Glass Cove
Marathon
Sea Glass Cove
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lower Matecumbe Key.
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

97000 Overseas Hwy Key Largo FL
CA $396
CA $525 total
Oct 18 - Oct 19
includes taxes & fees
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd Marathon FL
CA $287
CA $433 total
Oct 14 - Oct 15
includes taxes & fees
8.2/10 Very good! (1,004 reviews)
Hawks Cay Resort
Amara Cay Resort

Amara Cay Resort

80001 Overseas Hwy Islamorada FL
CA $207
CA $337 total
Oct 18 - Oct 19
includes taxes & fees
8.8/10 Excellent! (1,323 reviews)
Amara Cay Resort
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Lower Matecumbe Key

Check out the local area in Lower Matecumbe Key—home to attractions like Robbie’s of Islamorada and Anne's Beach.

See all hotels in Lower Matecumbe Key
A beach with a wooden pavilion, clear blue sky, and dense green foliage.

Top Lower Matecumbe Key Hotel Reviews

Cheeca Lodge & Spa

Cheeca Lodge & Spa

10/10 Excellent
"Staff is very helpful, rooms are clean, and there is a lot to do on the property!"
Morgan 2-night trip
Posted 1 hour ago
Cheeca Lodge & Spa

Find out more about Lower Matecumbe Key

Luxury is the name of the game at the best 5 Stars hotels in Lower Matecumbe Key. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Lower Matecumbe Key 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them.

Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Lower Matecumbe Key hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Lower Matecumbe Key without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Lower Matecumbe Key.

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