Title: 5 Stars Hotels in Downtown St. Louis, St. Louis from CA $205 - Find Cheap Downtown St. Louis Hotels With 5 Stars | Expedia.ca [Downtown St. Louis Travel Guide](https://expedia.ca/St-Louis-Downtown-St-Louis.dx800136)[Vacation Rentals in St. Louis](https://expedia.ca/St-Louis-Vacation-Rentals.d178309.Travel-Guide-VacationRentals)[Flights to St. Louis](https://expedia.ca/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.ca/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Downtown St. Louis Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-St-Louis.d800136.Car-Rental-Guide)[Downtown St. Louis Vacations](https://expedia.ca/Downtown-St-Louis.d800136.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478676-St-Louis-City-Missouri.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Downtown St. Louis, St. Louis from CA $205 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Downtown St. Louis 5 Star Hotels Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=800136&startDate=2025-09-27&endDate=2025-09-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=800136&startDate=2025-09-28&endDate=2025-09-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=800136&startDate=2025-10-03&endDate=2025-10-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=800136&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Downtown St. Louis 5 Star Hotels ![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/89e020ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/e177092f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/941b0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/5b370fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel St Louis Downtown St. Louis 9.4/10 Exceptional (1002) "Beautiful stay at the four seasons! " CA $592 CA $692 total includes taxes & fees Oct 4 - Oct 5 [](https://www.expedia.ca/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Downtown-St-Louis-St-Louis-Hotels.s50-n800136-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Downtown-St-Louis-St-Louis-Hotels.s50-n800136-0.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Downtown St. Louis. ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Regency St. Louis at The Arch 315 Chestnut St, St. Louis, MO CA $174 CA $205 total Oct 2 - Oct 3 includes taxes & fees 8.4/10 Very Good! (4,011 reviews) [](https://expedia.ca/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bb460692_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### 21C Museum Hotel St Louis 1528 Locust street, St. Louis, MO CA $210 CA $253 total Sep 30 - Oct 1 includes taxes & fees 9/10 Wonderful! (1,386 reviews) [](https://expedia.ca/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![St. Louis Union Station Hotel, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/8800/8738/171d52f3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### St. Louis Union Station Hotel, Curio Collection by Hilton 1820 Market Street, St. Louis, MO CA $240 CA $286 total Oct 5 - Oct 6 includes taxes & fees 8.4/10 Very Good! (1,015 reviews) [](https://expedia.ca/St-Louis-Hotels-St-Louis-Union-Station-Hotel.h8738.Hotel-Information) Still don't see what you're looking for? [See all properties in Downtown St. Louis.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=800136&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=800136&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=800136&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=800136&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=800136&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=800136&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Downtown St. Louis Hotel Reviews ![Four Seasons Hotel St Louis](//images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/89e020ab_y.jpg) ### Four Seasons Hotel St Louis 10/10 Excellent "Great help and classy property" [](https://expedia.ca/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) ## Frequently asked questions ### What are the best 5-star hotels in Downtown St. Louis? > Enjoy world-class amenities and the finest level of service at [Four Seasons Hotel St Louis](https://www.expedia.ca/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information). Located around the St. Louis neighbourhood of Downtown St. Louis, this 5-star hotel is a leading choice based on reviews by Expedia's customers. ### How much does it cost to stay in a 5-star hotel in Downtown St. Louis? > How much you pay for a 5-star hotel in Downtown St. Louis depends on things like when you want to go and the length of your stay. Our top tip for bagging an awesome deal? Use our pricing filters to check out the available accommodations for your selected dates. > > > > - Search for the lowest price per night from CA $205 ### What makes a hotel 5 stars in Downtown St. Louis? > Faultless guest service is at the heart of every 5-star hotel in Downtown St. Louis. From the moment you enter the lobby, staff attend to your every need, whether arranging customized tours or providing in-room massage treatments. Additionally, hotels must offer superior amenities to be considered for a 5-star rating. 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