A large, historic church with a tall bell tower and multiple domes.

4 Stars Hotels in Opelousas, Louisiana from CA $146

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Opelousas 4 Star Hotels

Tonight
Oct 1 - Oct 2
Tomorrow
Oct 2 - Oct 3
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Opelousas 4-star hotels

A bar area with a long counter, multiple bar stools, shelves with bottles, and a TV mounted above the bar.
A hotel room with a bed, a TV, a desk, a chair, a desk lamp, a bedside table with a lamp, a bathtub, and a window with curtains.
A hotel lobby with a grand staircase, a buffet table with floral centerpieces, and elegant lighting fixtures.
A spacious lobby with a staircase, seating area, and a reception desk.

1. DoubleTree by Hilton Hotel Lafayette

DoubleTree by Hilton Hotel Lafayette
Lafayette
United States
Tager
CA $127
CA $146 total
includes taxes & fees
Oct 25 - Oct 26
DoubleTree by Hilton Hotel Lafayette
A modern kitchen with grey cabinets, a central island with a sink, and a dining area with wicker chairs.
A modern two-story residential building with a garage, a small front yard, and a clear sky.
A modern kitchen with a marble island, grey cabinetry, and pendant lighting.
A row of modern townhouses with attached garages, a clear sky, and a well-maintained lawn.

2. Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
Lafayette
United States
Roderick
Enclave 3 Bedroom Luxury Homes
A small, single-story house with a porch and a wooden fence.
A bedroom with a large bed, a bathroom with a bathtub, and a view of trees through the window.
A dining area with a table set for two, a vase with flowers, and a painting on the wall.
A sunlit room with a table, two chairs, a vase with flowers, and a view of a green landscape through large windows.

3. Maison D'Memoire Bed & Breakfast Cottages

Maison D'Memoire Bed & Breakfast Cottages
Rayne
United Kingdom
Paul
CA $271
CA $307 total
includes taxes & fees
Oct 4 - Oct 5
Maison D'Memoire Bed & Breakfast Cottages
A spacious living area with a dining table, sofa, and a ceiling fan.
A wooden deck with a railing, two rocking chairs, and a view of a road and trees.
A bedroom with a bed, a nightstand, a lamp, a door, and a painting on the wall.
A modern, well-lit room with a dining table, wicker chairs, a sofa, and a large mirror on the wall.

4. The Royal Inn

The Royal Inn
Lafayette
United States
Yudeika
The Royal Inn
A modern kitchen with white cabinetry, gold handles, a built-in microwave, and a stove.
Two white Whirlpool washing machines in a laundry room with a shelf above containing cleaning supplies.
A green building with a white door labeled 'Decatur,' a window with blinds, and a wooden post.
A bedroom with a bed, bedside tables, a wall-mounted artwork, a window with blinds, and a door.

5. Decatur Inn

Decatur Inn
Lafayette
CA $210
CA $391 total
includes taxes & fees
Oct 13 - Oct 14
Decatur Inn
A modern kitchen with white cabinetry, a central island with seating, a microwave, stove, and refrigerator.
A bedroom with a bed, a nightstand, a dresser, and a painting on the wall.
A modern kitchen with white cabinets, a central island with bar stools, a gray sofa, and a round coffee table.
A pink building with a white door, a window with blinds, and the number 219.

6. Esplanade Inn

Esplanade Inn
Lafayette
Esplanade Inn
A spacious living area with a round dining table, a sofa, and a painting of a lake.
A modern loft with a dining area, a sofa, and a large mirror.
A wooden deck with a railing, a rocking chair, and a building with large windows.
A neatly made bed with a striped pillow, two bedside tables with lamps, and a framed picture on the wall.

7. Canal Inn

Canal Inn
Lafayette
Canal Inn
A spacious living area with a round dining table, a sofa, and a painting of a lake.
A neatly made bed with a striped pillow, two bedside tables with lamps, and a framed picture on the wall.
A two-story house with a balcony, a garage, and a driveway.
A modern loft with a dining area, a sofa, and a large mirror.

8. Canal Inn

Canal Inn
Lafayette
CA $154
CA $330 total
includes taxes & fees
Oct 12 - Oct 13
Canal Inn
A modern kitchen with white cabinetry, a central island with seating, a microwave, stove, and refrigerator.
A pink building with a white door, a window with blinds, and the number 219.
A laundry room with two Whirlpool washers, a small shelf with cleaning supplies, and a door leading to a bedroom with a bed and nightstand.
A modern kitchen with white cabinets, a central island with bar stools, a gray sofa, and a round coffee table.

9. Poydras Inn

Poydras Inn
Lafayette
CA $163
CA $341 total
includes taxes & fees
Oct 4 - Oct 5
Poydras Inn
A modern kitchen with white cabinets, stainless steel appliances, and a round wooden table with wicker chairs.
A bedroom with a bed, pillows, a window with blinds, a painting, and a view of greenery.
A modern apartment with a kitchen, dining area, and living room.
A building with a pink exterior, a white door labeled 'Bungalow,' and a window with blinds.

10. Rampart Inn

Rampart Inn
Lafayette
Rampart Inn
Lobby
Outdoor pool
Ballroom
Room

11. Wyndham Garden Lafayette

Wyndham Garden Lafayette
Lafayette
United States
Anonymous traveller
Wyndham Garden Lafayette
A modern kitchen with white cabinets, stainless steel appliances, a dishwasher, and a dining area with wicker chairs.
A bedroom with a bed, a nightstand, a lamp, a painting on the wall, and a door leading to a bathroom.
A laundry room with two front-loading washers, a dining area with chairs, and a hallway leading to another room.
A single-story building with a white door and a number '219' on the wall.

12. Iberville Inn

Iberville Inn
Lafayette
Iberville Inn
A row of modern multi-story residential buildings with attached garages, set against a backdrop of a grassy landscape and clear blue sky.
A bedroom with a white bed, two nightstands, a ceiling fan, a window with blinds, and a mirror.
A laundry area with a washing machine and dryer, a door leading to a bedroom with a bed and a window.
A modern bathroom with a white shower curtain, a white toilet, a vanity with a marble countertop, and a black faucet.

13. Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
Lafayette
Enclave 3 Bedroom Luxury Homes
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Opelousas

Spice up your visit to the Zydeco Capital with live music venues and the annual Zydeco Festival in late August. Explore Cajun food history at the Opelousas Museum, then sample authentic boudin and crawfish at family-owned restaurants locals recommend.

See all hotels in Opelousas
A large, historic church with a tall bell tower and multiple domes.

Top Opelousas Hotel Reviews

Find out more about Opelousas

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Opelousas are calling your name. Known for providing first-rate service in amazing locations, each of the Opelousas 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Opelousas. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Opelousas, Louisiana, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Opelousas hotels with 4 Stars provide everything you need to unwind in style.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Opelousas?
With Expedia's filter tool, scoring a fabulous deal on a 4-star hotel in Opelousas just got easier. Start by entering your chosen arrival date and length of your trip. Then list the results by price and choose the option that best matches your budget and style.
  • Search for the lowest price from CA $146
What's the difference between 5-star and 4-star hotels in Opelousas?
Offering an inviting traveller experience and upscale décor, 4-star hotels are a fantastic option for your Opelousas getaway. These kinds of accommodations generally feature loads of handy amenities that make it a breeze to unpack and unwind — think 24-hour room service, pools and gyms. Or live in the lap of luxury at a 5-star hotel designed to spoil you with luxury perks and amenities. Full-service health clubs, premium toiletries and world-class dining are typically included at these plush properties.
Does Opelousas have any 4-star all-inclusive resorts?
Enjoy a stress-free vacation experience where almost everything is included in the one upfront rate by using our "All inclusive" filter. Budgeting is a cinch when your room, food and many activities are already taken care of. Eager for more options? Check out the offers on Expedia's standard 4-star options in and around Opelousas too.

Explore a world of travel with Expedia