A beach with a wooden pavilion, clear blue sky, and dense green foliage.

4 Stars Hotels in Lower Matecumbe Key, Islamorada from CA $348

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Lower Matecumbe Key 4 Star Hotels

Tonight
Oct 20 - Oct 21
Tomorrow
Oct 21 - Oct 22
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Lower Matecumbe Key 4-star hotels

A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A beachfront hotel with multiple balconies, a pool, and a beach area with lounge chairs.
A child sitting on a beach with sand toys and a green bucket nearby.
Restaurant

1. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Alan
CA $389
CA $516 total
includes taxes & fees
Oct 22 - Oct 23
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A pathway leading to a pool area with palm trees and a sunset view.
An aerial view of a coastal resort with multiple white buildings, a clear turquoise sea, and lush greenery.
A spacious lobby with high ceilings, large windows, and a central coffee table surrounded by sofas and chairs.

2. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Antonio
CA $285
CA $429 total
includes taxes & fees
Oct 29 - Oct 30
Hawks Cay Resort
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A hotel room with a bed, a sofa, a coffee table, a desk with a lamp, and a view of the ocean.
A beach with palm trees, a dock, and lounge chairs.
A resort pool with palm trees, beach chairs, and umbrellas.

3. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
Ronald
CA $223
CA $354 total
includes taxes & fees
Nov 17 - Nov 18
Amara Cay Resort
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
A resort with a pool, beach, and ocean view.
A coastal resort with a beach, a swimming pool, and multiple buildings.
A beach with palm trees, a clear blue sky, and a calm sea.

4. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
United States
Liosbel
CA $337
CA $483 total
includes taxes & fees
Nov 2 - Nov 3
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A wooden pier leading to a beach with palm trees and a row of beach huts.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.
A paved pathway leading to a beach with palm trees and a view of the ocean.

5. Islander Resort

Islander Resort
Matecumbe
United States
Bryan
CA $242
CA $375 total
includes taxes & fees
Nov 15 - Nov 16
Islander Resort
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A beach with colorful buildings, kayaks, and lounge chairs.
A row of colorful beach huts with palm trees in the background.
A beach resort with palm trees, a thatched hut, and a purple building with a window.

6. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
CA $218
CA $348 total
includes taxes & fees
Nov 15 - Nov 16
La Siesta Resort & Villas
A wooden deck with a pool and chairs overlooking a beach with palm trees.
A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.
A beach with a wooden walkway leading to the water, palm trees, and a clear sky.
A bar area with stools, a counter, and hanging lanterns.

7. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
CA $272
CA $374 total
includes taxes & fees
Nov 19 - Nov 20
Grassy Flats Resort & Beach Club
A resort pool with palm trees and lounge chairs, surrounded by a beachfront.
An aerial view of a resort island with a large building, a swimming pool, and a boat docked nearby.
A modern kitchen with white cabinetry, a stainless steel oven, and a large island with a bowl of fruit.
A modern living room with a sofa, chairs, a dining table, a TV, and a view of the ocean.

8. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Gabriela
CA $648
CA $816 total
includes taxes & fees
Nov 16 - Nov 17
Villas At Hawks Cay Resort
A beach with palm trees, lounge chairs, and a thatched-roof structure.
A wooden deck with a thatched-roof structure, a sign indicating no swimming, and a clear view of the ocean.
A restaurant with a bar area, wooden ceiling, large windows, and potted plants.
A spacious living room with a dining area, a sofa, and a coffee table.

9. Condo in the Keys

Condo in the Keys
Tavernier
United States
Angela
Condo in the Keys
A modern kitchen with white cabinets, stainless steel appliances, and a granite countertop.
A kitchen with granite countertops, a stainless steel sink, a coffee maker, and a ceiling fan.
A covered outdoor area with two wooden chairs and a table, overlooking a beach and water.
A two-story residential building with a front porch, white picket fence, and well-maintained lawn.

10. Oceanfront Duck Key Villa: 2 Marinas Steps Away!

Oceanfront Duck Key Villa: 2 Marinas Steps Away!
Marathon
Oceanfront Duck Key Villa: 2 Marinas Steps Away!
Interior
A beach with clear turquoise water, a wooden pier, and a rocky shoreline.
A modern kitchen with a central island, bar stools, and a ceiling fan.
A modern kitchen with white cabinets, a microwave, and a dishwasher. There are three bar stools and a large window overlooking the ocean.

11. Florida Keys Getaway w/ Stunning Ocean Views

Florida Keys Getaway w/ Stunning Ocean Views
Long Key
CA $798
CA $1,481 total
includes taxes & fees
Oct 28 - Oct 29
Florida Keys Getaway w/ Stunning Ocean Views
Property grounds
Exterior
Private kitchen
Pool

12. Pineapple Beach by Florida Keys Luxury Rentals

Pineapple Beach by Florida Keys Luxury Rentals
Islamorada
Pineapple Beach by Florida Keys Luxury Rentals
Pool
Private kitchen
Private kitchen
Interior detail

13. Serenity by Florida Keys Luxury Rentals

Serenity by Florida Keys Luxury Rentals
Matecumbe
Serenity by Florida Keys Luxury Rentals
Beach
Exterior
Pool
Interior detail

14. Turtle Nest Estate by Florida Keys Luxury Rentals

Turtle Nest Estate by Florida Keys Luxury Rentals
Matecumbe
Turtle Nest Estate by Florida Keys Luxury Rentals
Balcony
Pool
Living room
Exterior

15. Midnight Runner by Florida Keys Luxury Rentals

Midnight Runner by Florida Keys Luxury Rentals
Tavernier
Midnight Runner by Florida Keys Luxury Rentals
Beach/ocean view
In-room dining
Property grounds
Property grounds

16. One-bedroom Apartment

One-bedroom Apartment
Marathon
One-bedroom Apartment
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Lower Matecumbe Key.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
CA $229
CA $362 total
Oct 22 - Oct 23
includes taxes & fees
Cheeca Lodge & Spa
The Islands of Islamorada

The Islands of Islamorada

82779 Old Hwy Islamorada FL
CA $677
CA $853 total
Oct 27 - Oct 28
includes taxes & fees
The Islands of Islamorada
Sea Glass Cove

Sea Glass Cove

59720 Overseas Hwy Marathon FL
Get ratesSea Glass Cove
Still don't see what you're looking for?
See all properties in Lower Matecumbe Key.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Lower Matecumbe Key

Check out the local area in Lower Matecumbe Key—home to attractions like Robbie’s of Islamorada and Anne's Beach.

See all hotels in Lower Matecumbe Key
A beach with a wooden pavilion, clear blue sky, and dense green foliage.

Top Lower Matecumbe Key Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

8/10 Good
"Lo mejor es la playa privada detras del hotel."
Abdel 3-night trip
Posted 2 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Hawks Cay Resort

Hawks Cay Resort

10/10 Excellent
"The place is very relaxing. Very clean. No bugs. Helpful polite staff. No complains at all. Just keep the fact that additional charges at check out are quite high."
Frederick 5-night trip
Posted 4 hours ago
Hawks Cay Resort
Islander Resort

Islander Resort

10/10 Excellent
"Resort was always clean during our stay. All of the staff were incredibly nice and helpful! Lots of activities on the property to keep you entertained."
Samuel 6-night trip
Posted 8 hours ago
Islander Resort
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

10/10 Excellent
"We've stayed at many places over the years . This place and the room that we had were the best . Waking up in bed to a view of the ocean can't be beat. It is situated on the most luxurious of all the keys.. can't wait to return ."
Tim 3-night trip
Posted 1 day ago
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Find out more about Lower Matecumbe Key

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Lower Matecumbe Key are calling your name. Known for providing first-rate service in amazing locations, each of the Lower Matecumbe Key 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Lower Matecumbe Key. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Lower Matecumbe Key, Islamorada, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Lower Matecumbe Key hotels with 4 Stars provide everything you need to unwind in style.

Explore a world of travel with Expedia