Title: Top 10 4 Star Hotels in Depew CA $131: Find a Four Star Hotel in Depew | Expedia.ca [Depew Travel Guide](https://expedia.ca/Depew.dx6338362)[Hotels in Depew](https://expedia.ca/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.ca/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.ca/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.ca/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Depew Car Rentals](https://expedia.ca/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.ca/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Depew 4 Star Hotels Tonight [Jan 15 - Jan 16](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-01-15&endDate=2026-01-16&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 16 - Jan 17](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-01-16&endDate=2026-01-17&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-01-23&endDate=2026-01-25&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Depew 4-star hotels ![2 restaurants, dinner served](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/c468db44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/bde63631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/2d8aa914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/16000000/15040000/15031200/15031117/f6195d5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Delavan Hotel & Spa [](https://www.expedia.ca/Buffalo-Hotels-The-Delavan-Hotel-Spa.h15031117.Hotel-Information) Bowmansville 9.0/10 Wonderful (1,000 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittany CA $215 CA $245 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Buffalo-Hotels-The-Delavan-Hotel-Spa.h15031117.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/28123e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/545d734b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily cooked-to-order breakfast](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/78ed955c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mansion On Delaware Ave [](https://www.expedia.ca/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) Downtown Buffalo 9.4/10 Exceptional (1,002 reviews) "Fantastic place!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Geneviève CA $221 CA $254 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3000/2914/3d573cc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/3000/2914/90ad8600.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3000/2914/8bfec9e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/3000/2914/06b0b650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Hotel Buffalo - Amherst [](https://www.expedia.ca/Buffalo-Hotels-DoubleTree-By-Hilton-Hotel-Buffalo-Amherst.h2914.Hotel-Information) Buffalo 7.8/10 Good (1,000 reviews) "Everything look great we will come back again😀" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheekeong CA $115 CA $131 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Buffalo-Hotels-DoubleTree-By-Hilton-Hotel-Buffalo-Amherst.h2914.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/7000000/6300000/6290200/6290133/2a49ee3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6300000/6290200/6290133/680cb22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6300000/6290200/6290133/276b91c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6300000/6290200/6290133/729fa626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mosey Buffalo Williamsville, Tapestry Collection by Hilton [](https://www.expedia.ca/Buffalo-Hotels-The-Mosey-Buffalo-Williamsville.h6290133.Hotel-Information) Buffalo 9.4/10 Exceptional (1,000 reviews) "Clean and spacious room and bathroom! Room service was spectacular! Easy check-in and check-out and parking was super convenient. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dana CA $198 CA $225 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Buffalo-Hotels-The-Mosey-Buffalo-Williamsville.h6290133.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/39700/39605/d1f34efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/40000/39700/39605/f1eaba86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![American cuisine](https://images.trvl-media.com/lodging/1000000/40000/39700/39605/05bfac67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/40000/39700/39605/834e24dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reikart House, Buffalo, a Tribute Portfolio Hotel [](https://www.expedia.ca/Buffalo-Hotels-Reikart-House.h39605.Hotel-Information) Buffalo 9.6/10 Exceptional (687 reviews) "Very nice hotel, well maintained, clean and high class. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $270 CA $307 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Buffalo-Hotels-Reikart-House.h39605.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/841778b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/c59b8ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/9e9840d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/26451150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Buffalo [](https://www.expedia.ca/Buffalo-Hotels-The-Westin-Buffalo.h13451237.Hotel-Information) Downtown Buffalo 9.2/10 Wonderful (405 reviews) "Very clean, nice staff, and great room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $347 CA $405 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/Buffalo-Hotels-The-Westin-Buffalo.h13451237.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/7bda029a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Robin Room](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/091461c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/27518664.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/e6c5cf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buffalo Harmony House [](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Harmony-House.h90762810.Hotel-Information) Downtown Buffalo 10/10 Exceptional (47 reviews) "Amazing breakfasts!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David [](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Harmony-House.h90762810.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/17000000/16210000/16201000/16200927/cbf5b2b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, soundproofing](https://images.trvl-media.com/lodging/17000000/16210000/16201000/16200927/761e8af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/17000000/16210000/16201000/16200927/9a62e340.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/17000000/16210000/16201000/16200927/3a915597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### River Spring Lodge [](https://www.expedia.ca/Attica-Hotels-River-Spring-Lodge.h16200927.Hotel-Information) Darien Center 10/10 Exceptional (76 reviews) "Will definitely recommend and stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carly [](https://www.expedia.ca/Attica-Hotels-River-Spring-Lodge.h16200927.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/6000000/5790000/5789500/5789437/816eaa06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/6000000/5790000/5789500/5789437/ffbe42b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/6000000/5790000/5789500/5789437/40a013a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/6000000/5790000/5789500/5789437/32f38975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lofts on Pearl Trademark Collection by Wyndham [](https://www.expedia.ca/Buffalo-Hotels-Lofts-On-Pearl-Trademark-Collection-By-Wyndham.h5789437.Hotel-Information) Downtown Buffalo 9.2/10 Wonderful (520 reviews) "Very easy and fast check in. Property manager managed to find ways to connect with me after unable to contact Expedia that our original property is closed on Sunday and we have to move to another property. The info provided was accurate. The location is really good. Close to city and easy access to metro even though due to COVID we didn’t take public transportation. We will definitely try the metro next time we are here." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy T. [](https://www.expedia.ca/Buffalo-Hotels-Lofts-On-Pearl-Trademark-Collection-By-Wyndham.h5789437.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Depew-Hotels.s40-0-d6338362.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Depew-Hotels.s40-0-d6338362.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Depew. ![Curtiss Hotel, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/1b8dbb7d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Curtiss Hotel, an Ascend Collection Hotel 210 Franklin St Buffalo NY CA $302 CA $353 total Jan 18 - Jan 19 includes taxes & fees 9.2/10 Wonderful! (1,001 reviews) [](https://expedia.ca/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) Still don't see what you're looking for? [See all properties in Depew.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F01%2F2026&endDate=17%2F01%2F2026®ionId=6338362&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F01%2F2026&endDate=17%2F01%2F2026®ionId=6338362&star=40&star=40&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F01%2F2026&endDate=17%2F01%2F2026®ionId=6338362&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F01%2F2026&endDate=17%2F01%2F2026®ionId=6338362&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F01%2F2026&endDate=17%2F01%2F2026®ionId=6338362&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=16%2F01%2F2026&endDate=17%2F01%2F2026®ionId=6338362&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Depew Hotel Reviews ## Find out more about Depew If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Depew are calling your name. Known for providing first-rate service in amazing locations, each of the Depew 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Depew. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Depew, Buffalo, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Depew hotels with 4 Stars provide everything you need to unwind in style. ## Frequently asked questions ### What are the best 4-star hotels in Depew? ### How much does it cost to stay in a 4-star hotel in Depew? > - Search for the lowest price from CA $353 ### What's the difference between 5-star and 4-star hotels in Depew? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [1 Star Hotels in Buffalo ](https://www.expedia.ca/1Star-Buffalo-Hotels.s10-0-d602674.Travel-Guide-Filter-Hotels) - [1 Star Hotels in Niagara Falls ](https://www.expedia.ca/1Star-Niagara-Falls-Hotels.s10-0-d602721.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Amherst ](https://www.expedia.ca/2Star-Amherst-Hotels.s20-0-d9323.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Buffalo ](https://www.expedia.ca/2Star-Buffalo-Hotels.s20-0-d602674.Travel-Guide-Filter-Hotels) - 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