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CA $203 Cheap Flights from Knoxville (TYS) to Buffalo (BUF)

View CA $203 flight on Tue, Sep 22, 2026Opens in a new window

Popular airlines from Alcoa - Knoxville Airport (TYS) to Buffalo Niagara Intl. Airport (BUF)

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Cheap flights from Knoxville (TYS) to Buffalo (BUF)

Prices were available within the past 7 days and start at CA $203 for one-way flights and CA $404 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Aug 24 - Sat, Aug 29
TYS
Knoxville
BUF
Buffalo
CA $404 Roundtrip, found 3 days ago
CA $404
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Aug 24 from Knoxville to Buffalo, returning Sat, Aug 29, priced at CA $404 found 3 days ago
Delta
Mon, Aug 24 - Sat, Aug 29
TYS
Knoxville
BUF
Buffalo
CA $404 Roundtrip, found 3 days ago
CA $404
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Aug 24 from Knoxville to Buffalo, returning Sat, Aug 29, priced at CA $404 found 3 days ago
Delta
Tue, Aug 25 - Fri, Sep 11
TYS
Knoxville
BUF
Buffalo
CA $406 Roundtrip, found 3 days ago
CA $406
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Aug 25 from Knoxville to Buffalo, returning Fri, Sep 11, priced at CA $406 found 3 days ago
Delta
Thu, Aug 27 - Sat, Sep 12
TYS
Knoxville
BUF
Buffalo
CA $423 Roundtrip, found 3 days ago
CA $423
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Aug 27 from Knoxville to Buffalo, returning Sat, Sep 12, priced at CA $423 found 3 days ago
Delta
Thu, Aug 27 - Fri, Sep 11
TYS
Knoxville
BUF
Buffalo
CA $424 Roundtrip, found 3 days ago
CA $424
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Aug 27 from Knoxville to Buffalo, returning Fri, Sep 11, priced at CA $424 found 3 days ago
Delta
Thu, Aug 27 - Thu, Sep 17
TYS
Knoxville
BUF
Buffalo
CA $441 Roundtrip, found 3 days ago
CA $441
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Aug 27 from Knoxville to Buffalo, returning Thu, Sep 17, priced at CA $441 found 3 days ago
American Airlines
Mon, Aug 24 - Sat, Aug 29
TYS
Knoxville
BUF
Buffalo
CA $448 Roundtrip, found 3 days ago
CA $448
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Aug 24 from Knoxville to Buffalo, returning Sat, Aug 29, priced at CA $448 found 3 days ago
Delta
Fri, Aug 28 - Fri, Sep 11
TYS
Knoxville
BUF
Buffalo
CA $449 Roundtrip, found 3 days ago
CA $449
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Aug 28 from Knoxville to Buffalo, returning Fri, Sep 11, priced at CA $449 found 3 days ago
Delta
Wed, Aug 19 - Mon, Aug 24
TYS
Knoxville
BUF
Buffalo
CA $458 Roundtrip, found 5 days ago
CA $458
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Aug 19 from Knoxville to Buffalo, returning Mon, Aug 24, priced at CA $458 found 5 days ago
United
Sat, Aug 22 - Sat, Sep 5
TYS
Knoxville
BUF
Buffalo
CA $517 Roundtrip, found 3 days ago
CA $517
Roundtrip
found 3 days ago
Select United flight, departing Sat, Aug 22 from Knoxville to Buffalo, returning Sat, Sep 5, priced at CA $517 found 3 days ago

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city centre is 16 minutes. Flights from CA $489
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city centre16 min
Flights from CA $489

Frequently asked questions

How much does a flight from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from CA $203 and cheap return flights from CA $404 TYS to BUF with Expedia. One-way flights typically cost between CA$223 and CA$873, and return flights often range between CA$626 and CA$1265. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when TYS to BUF ticket fares go up or down.
What is the cheapest month to fly from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you're looking for the cheapest time to fly from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.), March is typically your best bet. You can expect average return flights to be around CA$393 during this month. Other budget-friendly months for this route include January and August.
Which airlines fly direct from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter TYS to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting return flights from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.), with prices starting from around CA$405 for flights that can be booked for departure within the next year, with a layover in Nashville Intl. (BNA). These prices are per adult, for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest months to fly from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) are typically March and August, with average prices around CA$393 for a return flight. The most popular months for this route, indicating plenty of flight options, are October and May. While there isn't a single month that is both the cheapest and most popular, you can find good value in March and August, or more flight choices in October and May, allowing you to balance your budget with your schedule.
How many flights per day from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
There are approximately 46 connecting flights per day from McGhee Tyson (TYS) to Buffalo Niagara Intl. (BUF). Some common connection points include O'Hare Intl. (ORD), Hartsfield-Jackson Atlanta Intl. (ATL), and Washington Dulles Intl. (IAD).
What is the earliest flight from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) typically departs around 5:00 AM. This service is operated by American Airlines. This is a seasonal service active only in April. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You'll find the most flights from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) on a Friday, with around 31 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include American Airlines, Delta, and United. Fridays offer notably more flight options compared to other days of the week, making it a popular choice for travellers.
What are the most popular departure times for flights from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from McGhee Tyson (TYS) to Buffalo Niagara Intl. (BUF) are in the early morning, from 6am to 9am. Many major carriers, including American Airlines, Delta and Southwest Airlines, offer flights during this window. Many travellers prefer these times as it allows for an early start to their day at their destination.
How long does it take to fly from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
There are no nonstop flights from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.). The distance between these two cities is approximately 912 kilometres. Flights with one stop typically take around 4 hours 18 minutes. If you opt for flights with two or more stops, your travel time will be longer, usually around 10 hours. Keep in mind that actual flight times can vary due to factors like routing, weather, and wind patterns.
Can you fly business or first class from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Yes, you can fly business class or first class between TYS and BUF. You can fly business class with Delta.First class cabins are available on Delta, United, and American Airlines.
How do I earn miles on a Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo, NY (BUF) from Knoxville, TN (TYS)?
If you're planning to travel to Buffalo from McGhee Tyson (TYS), you can fly directly into Buffalo Niagara International Airport (BUF). Some flights may connect through major hubs like O'Hare International Airport (ORD), Charlotte-Douglas International Airport (CLT), or Washington Dulles International Airport (IAD) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Knoxville, TN (TYS-McGhee Tyson) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
McGhee Tyson
Destination airport
Buffalo Niagara Intl.
Roundtrip price
CA $403
Distance
906 km

Book with confidence

Alcoa to Buffalo Flights

The easy way to book your flights from Knoxville to Buffalo 

With Expedia, it’s simple to find and book flights to Buffalo from Knoxville whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Buffalo Niagara Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Knoxville to Buffalo today, tomorrow, or this week.  

 

Save dollars with cheap flights from McGhee Tyson, TYS to Buffalo Niagara Intl., BUF 

Sort your search results by price to find great deals on your flight from Knoxville to Buffalo—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Buffalo from Knoxville currently is just CA $404 rising to CA $517.  

Here are more money-saving tips: 

  • Fly in August when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Buffalo  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Buffalo from Knoxville 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Buffalo with Expedia today.

Alcoa to Buffalo Flights

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