CA $468 Cheap Flights from Panama City (PTY) to Buffalo (BUF)

View CA $468 flight on Mon, Nov 16, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Buffalo Niagara Intl. Airport (BUF)

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Cheap flights from Panama City (PTY) to Buffalo (BUF)

Prices were available within the past 7 days and start at CA $468 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
There are approximately 27 connecting flights per day from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.). Some common connection points include El Dorado Intl. (BOG), El Salvador Intl. (SAL), and Miami Intl. (MIA).
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) typically departs at approximately 2:55 AM local time. This service is seasonal, active only in November, and is operated by Avianca and JetBlue Airways. An early departure like this can help you maximize your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You'll typically find the most flights from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) on a Wednesday, with around 34 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Copa Airlines, Avianca, and United Airlines.
What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) are in the afternoon, from 3pm to 6pm. About 68% of passengers prefer this time. Many major carriers, including Delta and American Airlines, offer flights during this window. This timing works well because it allows you to have a productive morning before your flight and arrive at your destination in the evening.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Flying from PTY to BUF with a connection usually takes about 10 hours 20 minutes, traveling roughly 2,340 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Select the "Business class" and "First class" filters when looking for PTY to BUF flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Tocumen Intl. (PTY)?
From Tocumen Intl. (PTY), you can fly directly into Buffalo Niagara Intl. (BUF) to reach Buffalo. Some flights may connect through major hubs like Miami Intl. (MIA), Hartsfield-Jackson Atlanta Intl. (ATL), George Bush Intercontinental (IAH) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Panama City (PTY-Tocumen Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Buffalo Niagara Intl.
Distance
3744 km

Book with confidence

Tocumen to Buffalo Flights

The easy way to book your flights from Panama City to Buffalo 

With Expedia, it’s simple to find and book flights to Buffalo from Panama City whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Buffalo Niagara Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Panama City to Buffalo today, tomorrow, or this week.  

 

Save dollars with cheap flights from Tocumen Intl., PTY to Buffalo Niagara Intl., BUF 

Sort your search results by price to find great deals on your flight from Panama City to Buffalo—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Buffalo from Panama City currently is just rising to .  

Here are more money-saving tips: 

  • Fly in when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Buffalo  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Buffalo from Panama City 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Buffalo with Expedia today.

Tocumen to Buffalo Flights

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