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CA $215 Cheap Flights from Myrtle Beach (MYR) to Buffalo (BUF)

View CA $215 flight on Sat, Oct 31, 2026Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Buffalo Niagara Intl. Airport (BUF)

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Cheap flights from Myrtle Beach (MYR) to Buffalo (BUF)

Prices were available within the past 7 days and start at CA $215 for one-way flights and CA $428 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jan 12 - Sat, Jan 30
MYR
Myrtle Beach
BUF
Buffalo
CA $428 Roundtrip, found 22 hours ago
CA $428
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Jan 12 from Myrtle Beach to Buffalo, returning Sat, Jan 30, priced at CA $428 found 22 hours ago
Delta
Tue, Oct 13 - Sat, Oct 31
MYR
Myrtle Beach
BUF
Buffalo
CA $428 Roundtrip, found 22 hours ago
CA $428
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Oct 13 from Myrtle Beach to Buffalo, returning Sat, Oct 31, priced at CA $428 found 22 hours ago
American Airlines
Tue, Jan 12 - Fri, Jan 29
MYR
Myrtle Beach
BUF
Buffalo
CA $439 Roundtrip, found 22 hours ago
CA $439
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Jan 12 from Myrtle Beach to Buffalo, returning Fri, Jan 29, priced at CA $439 found 22 hours ago
Delta
Tue, Jan 12 - Sat, Jan 30
MYR
Myrtle Beach
BUF
Buffalo
CA $446 Roundtrip, found 22 hours ago
CA $446
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Jan 12 from Myrtle Beach to Buffalo, returning Sat, Jan 30, priced at CA $446 found 22 hours ago
American Airlines
Sat, Oct 24 - Fri, Oct 30
MYR
Myrtle Beach
BUF
Buffalo
CA $456 Roundtrip, found 22 hours ago
CA $456
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Sat, Oct 24 from Myrtle Beach to Buffalo, returning Fri, Oct 30, priced at CA $456 found 22 hours ago
Delta
Tue, Jan 12 - Fri, Jan 29
MYR
Myrtle Beach
BUF
Buffalo
CA $466 Roundtrip, found 22 hours ago
CA $466
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Jan 12 from Myrtle Beach to Buffalo, returning Fri, Jan 29, priced at CA $466 found 22 hours ago
American Airlines
Sat, Oct 24 - Fri, Oct 30
MYR
Myrtle Beach
BUF
Buffalo
CA $477 Roundtrip, found 22 hours ago
CA $477
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Sat, Oct 24 from Myrtle Beach to Buffalo, returning Fri, Oct 30, priced at CA $477 found 22 hours ago
American Airlines
Sat, Oct 24 - Fri, Oct 30
MYR
Myrtle Beach
BUF
Buffalo
CA $482 Roundtrip, found 22 hours ago
CA $482
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Sat, Oct 24 from Myrtle Beach to Buffalo, returning Fri, Oct 30, priced at CA $482 found 22 hours ago
Delta
Tue, Oct 13 - Sat, Oct 31
MYR
Myrtle Beach
BUF
Buffalo
CA $484 Roundtrip, found 22 hours ago
CA $484
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Oct 13 from Myrtle Beach to Buffalo, returning Sat, Oct 31, priced at CA $484 found 22 hours ago
United
Tue, Jan 12 - Fri, Jan 29
MYR
Myrtle Beach
BUF
Buffalo
CA $495 Roundtrip, found 22 hours ago
CA $495
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 12 from Myrtle Beach to Buffalo, returning Fri, Jan 29, priced at CA $495 found 22 hours ago

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city centre is 16 minutes. Flights from CA $581
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city centre16 min
Flights from CA $581

Frequently asked questions

How much does a flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from CA $215 and cheap return flights from CA $428 MYR to BUF with Expedia. One-way flights typically cost between CA$274 and CA$750. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when MYR to BUF ticket fares go up or down.
What is the cheapest month to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
March is typically the cheapest month to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), with average return fares around CA$356. March often sees lower prices as it's before the peak summer travel season, when demand tends to increase. Other cheap months to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) include May and September.
Which airlines fly direct from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter MYR to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting return flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), with prices starting from around CA$382 for flights that can be booked for departure within the next year, including a layover in Baltimore Washington Intl. Thurgood Marshall (BWI). These prices are for one adult in economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly from Myrtle Beach International Airport (MYR) to Buffalo Niagara International Airport (BUF) is typically March or September. These months offer a great balance—prices are reasonable at around CA$356 for a return flight, and you'll have plenty of flight options since they're popular times to travel. March offers a pleasant start to spring, while September brings comfortable early autumn weather. If you're flexible, these months give you both affordable fares and excellent flight schedules to work with.
How many flights per day from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
There are approximately 30 connecting flights per day from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.). Some common connection points include Hartsfield-Jackson Atlanta Intl. (ATL), Charlotte-Douglas Intl. (CLT), and Baltimore Washington Intl. Thurgood Marshall (BWI).
What is the earliest flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Myrtle Beach International Airport (MYR) to Buffalo Niagara International Airport (BUF) typically departs around 5:00 AM. This flight is operated by American Airlines and is a seasonal service, active in December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You'll typically find the most flights from Myrtle Beach, SC (MYR) to Buffalo, NY (BUF) on a Thursday, with around 21 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include American Airlines, Delta, and Southwest Airlines. Flight schedules are quite consistent throughout the week, so you'll have plenty of options no matter which day you choose to fly.
What are the most popular departure times for flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) are in the morning, from 9am to 12pm. Many major carriers, including Delta, American Airlines and United, offer flights during this window. Many travellers prefer these times as they allow for an early start to their journey, getting you to your destination with plenty of time left in the day.
How long does it take to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
There are no nonstop flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.). Flights with one stop typically take around 3 hours 50 minutes, covering a distance of about 1,028 kilometres. Flights with two or more stops will take longer, usually around 10 hours 30 minutes. Keep in mind that these are average travel times, and your actual flight duration can vary based on the specific routing, layover times, and factors like wind patterns.
Can you fly business or first class from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You can fly first class between MYR and BUF. First class cabins are available on United, Delta, and American Airlines.
How do I earn miles on a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo, NY (BUF) from Myrtle Beach, SC (MYR)?
If you're planning to travel to Buffalo from MYR, you can fly directly into Buffalo Niagara International Airport (BUF) which offers international flights and connections. Some flights may connect through major hubs like Liberty International Airport (EWR), Charlotte-Douglas International Airport (CLT), or Hartsfield-Jackson Atlanta International Airport (ATL) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
CA $428
Distance
1022 km

Book with confidence

Myrtle Beach to Buffalo Flights

The easy way to book your flights from Myrtle Beach to Buffalo 

With Expedia, it’s simple to find and book flights to Buffalo from Myrtle Beach whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Buffalo Niagara Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Myrtle Beach to Buffalo today, tomorrow, or this week.  

 

Save dollars with cheap flights from Myrtle Beach Intl., MYR to Buffalo Niagara Intl., BUF 

Sort your search results by price to find great deals on your flight from Myrtle Beach to Buffalo—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Buffalo from Myrtle Beach currently is just CA $428 rising to CA $495.  

Here are more money-saving tips: 

  • Fly in January when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Buffalo  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Buffalo from Myrtle Beach 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Buffalo with Expedia today.

Myrtle Beach to Buffalo Flights

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