Cheap flights from Des Moines to West Syracuse from CA $225

View CA $225 flight on Tue, Jul. 15, 2025Opens in a new window

Popular airlines from Des Moines to West Syracuse

  • American Airlines

    American Airlines

  • Delta

    Delta

  • United

    United

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Cheap flights from Des Moines (DSM) to West Syracuse (SYR)

Prices were available within the past 7 days and start at CA $225 for one-way flights and CA $353 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Jul. 30 - Wed, Aug. 13
DSM
Des Moines
SYR
Syracuse
CA $353 Roundtrip, found 17 hours ago
CA $353
Roundtrip
found 17 hours ago
Select Delta flight, departing Wed, Jul. 30 from Des Moines to Syracuse, returning Wed, Aug. 13, priced at CA $353 found 17 hours ago
Delta
Mon, Jul. 28 - Wed, Aug. 13
DSM
Des Moines
SYR
Syracuse
CA $374 Roundtrip, found 17 hours ago
CA $374
Roundtrip
found 17 hours ago
Select Delta flight, departing Mon, Jul. 28 from Des Moines to Syracuse, returning Wed, Aug. 13, priced at CA $374 found 17 hours ago
Delta
Wed, Jul. 30 - Fri, Aug. 15
DSM
Des Moines
SYR
Syracuse
CA $380 Roundtrip, found 17 hours ago
CA $380
Roundtrip
found 17 hours ago
Select Delta flight, departing Wed, Jul. 30 from Des Moines to Syracuse, returning Fri, Aug. 15, priced at CA $380 found 17 hours ago
Delta
Mon, Jul. 28 - Fri, Aug. 15
DSM
Des Moines
SYR
Syracuse
CA $401 Roundtrip, found 17 hours ago
CA $401
Roundtrip
found 17 hours ago
Select Delta flight, departing Mon, Jul. 28 from Des Moines to Syracuse, returning Fri, Aug. 15, priced at CA $401 found 17 hours ago
American Airlines
Wed, Jul. 30 - Mon, Aug. 18
DSM
Des Moines
SYR
Syracuse
CA $449 Roundtrip, found 17 hours ago
CA $449
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Wed, Jul. 30 from Des Moines to Syracuse, returning Mon, Aug. 18, priced at CA $449 found 17 hours ago
United
Thu, Jul. 31 - Thu, Aug. 14
DSM
Des Moines
SYR
Syracuse
CA $523 Roundtrip, found 17 hours ago
CA $523
Roundtrip
found 17 hours ago
Select United flight, departing Thu, Jul. 31 from Des Moines to Syracuse, returning Thu, Aug. 14, priced at CA $523 found 17 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Syracuse (SYR)

April is typically the cheapest month to fly

From CA $271 - CA $803 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.