Cheap flights from Des Moines to Bay Area from CA $213

View CA $213 flight on Thu, Aug. 28, 2025Opens in a new window

Popular airlines from Des Moines to Bay Area

  • Frontier Airlines

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  • United

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  • American Airlines

    American Airlines

  • Delta

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  • Southwest Airlines

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  • Alaska Airlines

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Cheap flights from Des Moines (DSM) to Bay Area (SJC)

Prices were available within the past 7 days and start at CA $213 for one-way flights and CA $1,200 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Aug. 1 - Sat, Aug. 2
DSM
Des Moines
SFO
San Francisco
CA $1,200 Roundtrip, found 2 days ago
CA $1,200
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Aug. 1 from Des Moines to San Francisco, returning Sat, Aug. 2, priced at CA $1,200 found 2 days ago
Delta
Fri, Aug. 1 - Sat, Aug. 2
DSM
Des Moines
SFO
San Francisco
CA $1,242 Roundtrip, found 2 days ago
CA $1,242
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug. 1 from Des Moines to San Francisco, returning Sat, Aug. 2, priced at CA $1,242 found 2 days ago
Delta
Fri, Aug. 1 - Sat, Aug. 2
DSM
Des Moines
SFO
San Francisco
CA $1,251 Roundtrip, found 2 days ago
CA $1,251
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug. 1 from Des Moines to San Francisco, returning Sat, Aug. 2, priced at CA $1,251 found 2 days ago
Delta
Fri, Aug. 1 - Sat, Aug. 2
DSM
Des Moines
SFO
San Francisco
CA $1,258 Roundtrip, found 2 days ago
CA $1,258
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug. 1 from Des Moines to San Francisco, returning Sat, Aug. 2, priced at CA $1,258 found 2 days ago
American Airlines
Fri, Aug. 1 - Sat, Aug. 2
DSM
Des Moines
SFO
San Francisco
CA $1,338 Roundtrip, found 2 days ago
CA $1,338
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Aug. 1 from Des Moines to San Francisco, returning Sat, Aug. 2, priced at CA $1,338 found 2 days ago
Delta
Fri, Aug. 1 - Sat, Aug. 2
DSM
Des Moines
SFO
San Francisco
CA $1,355 Roundtrip, found 2 days ago
CA $1,355
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug. 1 from Des Moines to San Francisco, returning Sat, Aug. 2, priced at CA $1,355 found 2 days ago

Find the cheapest month to fly from Des Moines (DSM) to San Francisco (SFO)

September is typically the cheapest month to fly

From CA $162 - CA $588 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.