Cheap flights from Des Moines to Isla Holbox from CA $307

View CA $307 flight on Sat, Aug. 16, 2025Opens in a new window

Popular airlines from Des Moines to Isla Holbox

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Cheap flights from Des Moines (DSM) to Isla Holbox (CUN)

Prices were available within the past 7 days and start at CA $307 for one-way flights and CA $892 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Aug. 2 - Fri, Aug. 8
DSM
Des Moines
CUN
Cancun
CA $892 Roundtrip, found 2 days ago
CA $892
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug. 2 from Des Moines to Cancun, returning Fri, Aug. 8, priced at CA $892 found 2 days ago
Delta
Sat, Aug. 2 - Fri, Aug. 8
DSM
Des Moines
CUN
Cancun
CA $919 Roundtrip, found 2 days ago
CA $919
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Aug. 2 from Des Moines to Cancun, returning Fri, Aug. 8, priced at CA $919 found 2 days ago
American Airlines
Sat, Aug. 2 - Fri, Aug. 8
DSM
Des Moines
CUN
Cancun
CA $926 Roundtrip, found 2 days ago
CA $926
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug. 2 from Des Moines to Cancun, returning Fri, Aug. 8, priced at CA $926 found 2 days ago
American Airlines
Sat, Aug. 2 - Fri, Aug. 8
DSM
Des Moines
CUN
Cancun
CA $940 Roundtrip, found 2 days ago
CA $940
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug. 2 from Des Moines to Cancun, returning Fri, Aug. 8, priced at CA $940 found 2 days ago
American Airlines
Sat, Aug. 2 - Fri, Aug. 8
DSM
Des Moines
CUN
Cancun
CA $947 Roundtrip, found 2 days ago
CA $947
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug. 2 from Des Moines to Cancun, returning Fri, Aug. 8, priced at CA $947 found 2 days ago
American Airlines
Sat, Aug. 2 - Fri, Aug. 8
DSM
Des Moines
CUN
Cancun
CA $960 Roundtrip, found 2 days ago
CA $960
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug. 2 from Des Moines to Cancun, returning Fri, Aug. 8, priced at CA $960 found 2 days ago

Find the cheapest month to fly from Des Moines (DSM) to Cancun (CUN)

November is typically the cheapest month to fly

From CA $465 - CA $1,076 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.