Cheap flights from Indianapolis to San Diego from CA $161

View CA $161 flight on Thu, Sep. 11, 2025Opens in a new window

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Cheap flights from Indianapolis (IND) to San Diego (SAN)

Prices were available within the past 7 days and start at CA $161 for one-way flights and CA $330 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Thu, Sep. 11 - Sun, Sep. 14
IND
Indianapolis
SAN
San Diego
CA $330 Roundtrip, found 1 day ago
CA $330
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Sep. 11 from Indianapolis to San Diego, returning Sun, Sep. 14, priced at CA $330 found 1 day ago
Spirit Airlines
Thu, Sep. 11 - Sun, Sep. 14
IND
Indianapolis
SAN
San Diego
CA $421 Roundtrip, found 1 day ago
CA $421
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Sep. 11 from Indianapolis to San Diego, returning Sun, Sep. 14, priced at CA $421 found 1 day ago
Alaska Airlines
Thu, Sep. 11 - Sun, Sep. 14
IND
Indianapolis
SAN
San Diego
CA $425 Roundtrip, found 1 day ago
CA $425
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Thu, Sep. 11 from Indianapolis to San Diego, returning Sun, Sep. 14, priced at CA $425 found 1 day ago
Alaska Airlines
Thu, Sep. 11 - Sun, Sep. 14
IND
Indianapolis
SAN
San Diego
CA $444 Roundtrip, found 1 day ago
CA $444
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Thu, Sep. 11 from Indianapolis to San Diego, returning Sun, Sep. 14, priced at CA $444 found 1 day ago
Spirit Airlines
Thu, Sep. 11 - Sun, Sep. 14
IND
Indianapolis
SAN
San Diego
CA $494 Roundtrip, found 1 day ago
CA $494
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Sep. 11 from Indianapolis to San Diego, returning Sun, Sep. 14, priced at CA $494 found 1 day ago
Alaska Airlines
Thu, Sep. 11 - Sun, Sep. 14
IND
Indianapolis
SAN
San Diego
CA $503 Roundtrip, found 1 day ago
CA $503
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Thu, Sep. 11 from Indianapolis to San Diego, returning Sun, Sep. 14, priced at CA $503 found 1 day ago

Find the cheapest month to fly from Indianapolis (IND) to San Diego (SAN)

September is typically the cheapest month to fly

From CA $139 - CA $292 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.