A large waterfall cascading down a cliff, surrounded by dense forest and rocky terrain.

CA $214 Cheap Flights from Greenville (GSP) to Buffalo (BUF)

View CA $214 flight on Sun, Sep 6, 2026Opens in a new window

Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to Buffalo Niagara Intl. Airport (BUF)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Greenville (GSP) to Buffalo (BUF)

Prices were available within the past 7 days and start at CA $214 for one-way flights and CA $426 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sun, Sep 6 - Wed, Sep 9
GSP
Greenville
BUF
Buffalo
CA $426 Roundtrip, found 6 days ago
CA $426
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Sep 6 from Greenville to Buffalo, returning Wed, Sep 9, priced at CA $426 found 6 days ago
Delta
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $443 Roundtrip, found 5 days ago
CA $443
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $443 found 5 days ago
Delta
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $444 Roundtrip, found 5 days ago
CA $444
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $444 found 5 days ago
American Airlines
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $450 Roundtrip, found 5 days ago
CA $450
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $450 found 5 days ago
American Airlines
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $477 Roundtrip, found 5 days ago
CA $477
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $477 found 5 days ago
Delta
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $485 Roundtrip, found 5 days ago
CA $485
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $485 found 5 days ago
American Airlines
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $487 Roundtrip, found 5 days ago
CA $487
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $487 found 5 days ago
American Airlines
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $494 Roundtrip, found 5 days ago
CA $494
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $494 found 5 days ago
American Airlines
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $496 Roundtrip, found 5 days ago
CA $496
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $496 found 5 days ago
American Airlines
Tue, Sep 15 - Fri, Sep 25
GSP
Greenville
BUF
Buffalo
CA $499 Roundtrip, found 5 days ago
CA $499
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Sep 15 from Greenville to Buffalo, returning Fri, Sep 25, priced at CA $499 found 5 days ago

Frequently asked questions

How much does a flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from CA $214 and cheap return flights from CA $426 GSP to BUF with Expedia. Return flights often range between CA$415 and CA$1331. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when GSP to BUF ticket fares go up or down.
What is the cheapest month to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest months to fly from GSP to BUF are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter GSP to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting return flights from Greenville-Spartanburg Intl. (GSP) to Buffalo Niagara Intl. (BUF), with prices starting from around CA$373 for flights that can be booked for departure within the next year, with a layover in Nashville Intl. (BNA). These prices are per adult, for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
There are approximately 47 connecting flights per day from Greenville-Spartanburg Intl. (GSP) to Buffalo Niagara Intl. (BUF). Some common connection points include O'Hare Intl. (ORD), Hartsfield-Jackson Atlanta Intl. (ATL), and Charlotte-Douglas Intl. (CLT).
What is the earliest flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Greenville-Spartanburg Intl. (GSP) to Buffalo Niagara Intl. (BUF) typically departs around 5:00 AM. This flight is operated by American Airlines. This is a seasonal service, active only in October. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You'll generally find the most flights from Greenville-Spartanburg Intl. (GSP) to Buffalo Niagara Intl. (BUF) on a Thursday, with around 33 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include American Airlines, Delta, and United. Flight schedules are quite consistent throughout the week, so you'll have plenty of options regardless of your travel day.
What are the most popular departure times for flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) are in the early morning, from 6am to 9am. Many major carriers, including American Airlines, Delta and Southwest Airlines, offer flights during this window. Many travelers prefer this because it allows for an early start to their travel day, often leading to an earlier arrival at their destination.
How long does it take to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
There are no nonstop flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.). For flights with one stop, you can expect the journey to take around 4 hours, covering a distance of approximately 943 kilometres. Flights with two or more stops typically take longer, averaging about 7 hours 48 minutes. Keep in mind that these are average travel times, and your actual flight duration can vary depending on the specific routing, layover times, and even weather conditions.
Can you fly business or first class from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You can fly first class between GSP and BUF. First class cabins are available on United, Delta, and American Airlines.
How do I earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo, NY (BUF) from Greenville, SC (GSP)?
If you're planning to travel to Buffalo from Greenville-Spartanburg Intl. (GSP), you can fly directly into Buffalo Niagara Intl. (BUF) which offers international flights and connections. Some flights may connect through major hubs like O'Hare Intl. (ORD), Washington Dulles Intl. (IAD), or Liberty Intl. (EWR) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Greenville-Spartanburg Intl.
Destination airport
Buffalo Niagara Intl.
Roundtrip price
CA $425
Distance
938 km

Book with confidence

Greer to Buffalo Flights

The easy way to book your flights from Greenville to Buffalo 

With Expedia, it’s simple to find and book flights to Buffalo from Greenville whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Buffalo Niagara Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Greenville to Buffalo today, tomorrow, or this week.  

 

Save dollars with cheap flights from Greenville-Spartanburg Intl., GSP to Buffalo Niagara Intl., BUF 

Sort your search results by price to find great deals on your flight from Greenville to Buffalo—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Buffalo from Greenville currently is just CA $426 rising to CA $499.  

Here are more money-saving tips: 

  • Fly in September when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Buffalo  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Buffalo from Greenville 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Buffalo with Expedia today.

Greer to Buffalo Flights

Explore a world of travel with Expedia

*Available to Expedia members.