CA $816 Cheap Flights from Buffalo (BUF) to Santiago (SCL)

View CA $816 flight on Mon, Jul 13, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Santiago Intl. Airport (SCL)

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Cheap flights from Buffalo (BUF) to Santiago (SCL)

Prices were available within the past 7 days and start at CA $816 for one-way flights and CA $1,616 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Jun 25 - Thu, Jul 2
BUF
Buffalo
SCL
Santiago
CA $1,616 Roundtrip, found 3 days ago
CA $1,616
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Jun 25 from Buffalo to Santiago, returning Thu, Jul 2, priced at CA $1,616 found 3 days ago
American Airlines
Fri, Jun 26 - Sun, Jul 26
BUF
Buffalo
SCL
Santiago
CA $1,659 Roundtrip, found 3 hours ago
CA $1,659
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Jun 26 from Buffalo to Santiago, returning Sun, Jul 26, priced at CA $1,659 found 3 hours ago
LATAM Airlines Group
Tue, Jun 30 - Tue, Jul 7
BUF
Buffalo
SCL
Santiago
CA $1,663 Roundtrip, found 3 days ago
CA $1,663
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Jun 30 from Buffalo to Santiago, returning Tue, Jul 7, priced at CA $1,663 found 3 days ago
Delta
Thu, Jun 25 - Sat, Jul 4
BUF
Buffalo
SCL
Santiago
CA $1,685 Roundtrip, found 3 days ago
CA $1,685
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Jun 25 from Buffalo to Santiago, returning Sat, Jul 4, priced at CA $1,685 found 3 days ago
American Airlines
Sun, Jun 28 - Sat, Jul 4
BUF
Buffalo
SCL
Santiago
CA $1,698 Roundtrip, found 3 days ago
CA $1,698
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sun, Jun 28 from Buffalo to Santiago, returning Sat, Jul 4, priced at CA $1,698 found 3 days ago
American Airlines
Sun, Jun 28 - Sat, Jul 4
BUF
Buffalo
SCL
Santiago
CA $1,706 Roundtrip, found 3 days ago
CA $1,706
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sun, Jun 28 from Buffalo to Santiago, returning Sat, Jul 4, priced at CA $1,706 found 3 days ago
LATAM Airlines Group
Sun, Jun 28 - Sat, Jul 4
BUF
Buffalo
SCL
Santiago
CA $1,721 Roundtrip, found 3 days ago
CA $1,721
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, Jun 28 from Buffalo to Santiago, returning Sat, Jul 4, priced at CA $1,721 found 3 days ago
Delta
Sun, Jun 28 - Sat, Jul 4
BUF
Buffalo
SCL
Santiago
CA $1,746 Roundtrip, found 3 days ago
CA $1,746
Roundtrip
found 3 days ago
Select Delta flight, departing Sun, Jun 28 from Buffalo to Santiago, returning Sat, Jul 4, priced at CA $1,746 found 3 days ago
JetBlue Airways
Fri, Jun 26 - Sun, Jul 26
BUF
Buffalo
SCL
Santiago
CA $1,781 Roundtrip, found 3 hours ago
CA $1,781
Roundtrip
found 3 hours ago
Select JetBlue Airways flight, departing Fri, Jun 26 from Buffalo to Santiago, returning Sun, Jul 26, priced at CA $1,781 found 3 hours ago
avianca
Fri, Jun 26 - Sun, Jul 26
BUF
Buffalo
SCL
Santiago
CA $2,476 Roundtrip, found 3 hours ago
CA $2,476
Roundtrip
found 3 hours ago
Select avianca flight, departing Fri, Jun 26 from Buffalo to Santiago, returning Sun, Jul 26, priced at CA $2,476 found 3 hours ago

Frequently asked questions

How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There are approximately 19 connecting flights per day from Buffalo Niagara Intl. (BUF) to Arturo Merino Benitez (SCL). Some common connection points include John F. Kennedy Intl. (JFK), Orlando Intl. (MCO), and Logan Intl. (BOS).
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Buffalo Niagara Intl. (BUF) to Arturo Merino Benitez (SCL) typically departs at approximately 5:15 AM local time. This service is operated by American Airlines and is seasonal, active only in March. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
If you're flying from Buffalo Niagara Intl. (BUF) to Santiago (SCL), you'll generally find the most flights on a Thursday, with around 35 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include United Airlines, Delta Air Lines, and American Airlines. Looking at the overall week, Thursday offers notably more flight options compared to other days.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Buffalo Niagara Intl. (BUF) to Arturo Merino Benitez (SCL) are between 12pm and 3pm. This accounts for around 49% of total traffic. Many major carriers, including American Airlines, Delta and United Airlines, offer flights during this window. Many travelers prefer this because it allows for a midday departure, giving you time in the morning before your flight and an evening arrival at your destination.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Flights from BUF to SCL with one stop typically take around 23 hours 50 minutes, covering approximately 5,298 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Select the "Business class" and "First class" filters when looking for BUF to SCL flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago from Buffalo Niagara Intl. (BUF)?
When traveling from Buffalo Niagara Intl. (BUF) to Santiago, you can fly into Cibao Intl. (STI) and Arturo Merino Benitez (SCL). Some flights may connect through major hubs like Charlotte-Douglas Intl. (CLT), Ronald Reagan Washington National (DCA), O'Hare Intl. (ORD) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to Santiago (SCL-Arturo Merino Benitez) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Arturo Merino Benitez
Roundtrip price
CA $1,616
Distance
8476 km

Book with confidence

Buffalo to Santiago Flights

The easy way to book your flights from Buffalo to Santiago 

With Expedia, it’s simple to find and book flights to Santiago from Buffalo whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Arturo Merino Benitez, too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Buffalo to Santiago today, tomorrow, or this week.  

 

Save dollars with cheap flights from Buffalo Niagara Intl., BUF to Arturo Merino Benitez, SCL 

Sort your search results by price to find great deals on your flight from Buffalo to Santiago—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Santiago from Buffalo currently is just CA $1,616 rising to CA $2,476.  

Here are more money-saving tips: 

  • Fly in June when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Santiago  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Santiago from Buffalo 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Santiago with Expedia today.

Buffalo to Santiago Flights

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*Available to Expedia members.