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CA $345 Cheap Flights from Quito (UIO) to Santiago (SCL)

View CA $345 flight on Wed, Nov 11, 2026Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Santiago Intl. Airport (SCL)

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Cheap flights from Quito (UIO) to Santiago (SCL)

Prices were available within the past 7 days and start at CA $345 for one-way flights and CA $707 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Mon, Oct 5 - Wed, Oct 14
UIO
Quito
SCL
Santiago
CA $707 Roundtrip, found 3 days ago
CA $707
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Mon, Oct 5 from Quito to Santiago, returning Wed, Oct 14, priced at CA $707 found 3 days ago
Jetsmart SPA
Wed, Oct 28 - Wed, Nov 4
UIO
Quito
SCL
Santiago
CA $727 Roundtrip, found 4 days ago
CA $727
Roundtrip
found 4 days ago
Select Jetsmart SPA flight, departing Wed, Oct 28 from Quito to Santiago, returning Wed, Nov 4, priced at CA $727 found 4 days ago
Jetsmart SPA
Fri, Sep 4 - Sun, Sep 6
UIO
Quito
SCL
Santiago
CA $754 Roundtrip, found 5 days ago
CA $754
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Fri, Sep 4 from Quito to Santiago, returning Sun, Sep 6, priced at CA $754 found 5 days ago
LATAM Airlines Group
Wed, Oct 28 - Tue, Nov 3
UIO
Quito
SCL
Santiago
CA $761 Roundtrip, found 4 days ago
CA $761
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 28 from Quito to Santiago, returning Tue, Nov 3, priced at CA $761 found 4 days ago
LATAM Airlines Group
Wed, Oct 28 - Wed, Nov 4
UIO
Quito
SCL
Santiago
CA $768 Roundtrip, found 4 days ago
CA $768
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 28 from Quito to Santiago, returning Wed, Nov 4, priced at CA $768 found 4 days ago
LATAM Airlines Group
Wed, Oct 28 - Tue, Nov 3
UIO
Quito
SCL
Santiago
CA $776 Roundtrip, found 4 days ago
CA $776
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 28 from Quito to Santiago, returning Tue, Nov 3, priced at CA $776 found 4 days ago
LATAM Airlines Group
Thu, Oct 29 - Mon, Nov 9
UIO
Quito
SCL
Santiago
CA $776 Roundtrip, found 1 day ago
CA $776
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Thu, Oct 29 from Quito to Santiago, returning Mon, Nov 9, priced at CA $776 found 1 day ago
LATAM Airlines Group
Mon, Oct 5 - Wed, Oct 14
UIO
Quito
SCL
Santiago
CA $779 Roundtrip, found 3 days ago
CA $779
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, Oct 5 from Quito to Santiago, returning Wed, Oct 14, priced at CA $779 found 3 days ago
LATAM Airlines Group
Wed, Oct 28 - Tue, Nov 3
UIO
Quito
SCL
Santiago
CA $780 Roundtrip, found 4 days ago
CA $780
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 28 from Quito to Santiago, returning Tue, Nov 3, priced at CA $780 found 4 days ago
avianca
Tue, Aug 18 - Tue, Aug 25
UIO
Quito
SCL
Santiago
CA $783 Roundtrip, found 4 days ago
CA $783
Roundtrip
found 4 days ago
Select avianca flight, departing Tue, Aug 18 from Quito to Santiago, returning Tue, Aug 25, priced at CA $783 found 4 days ago

Frequently asked questions

How much does a flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) cost?
You can find cheap one-way flights from CA $345 and cheap return flights from CA $707 UIO to SCL with Expedia. One-way flights typically cost between CA$460 and CA$1318, and return flights often range between CA$789 and CA$2010. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when UIO to SCL ticket fares go up or down.
What is the cheapest month to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
May is typically the cheapest month to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez), with average return fares around CA$766. May often sees lower prices because it falls outside of peak holiday seasons, when demand tends to be lower, allowing airlines to offer more competitive fares. Other cheap months to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) include September and November.
Which airlines fly direct from Quito (UIO) to Santiago (SCL)?
Enter UIO to SCL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Quito (UIO) to Santiago (SCL)?
To find a cheap flight from Quito (UIO) to Santiago (SCL), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The best time to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) is typically May or September. These months offer a great balance, with return flights averaging around CA$766. While these might not be the absolute cheapest months, they often provide a good combination of reasonable fares and plenty of flight options, as they are popular times to travel. If you're flexible, these months give you both good value and excellent flight schedules to work with.
How many flights per day from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There are approximately 28 connecting flights per day from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez). Some common connection points include Jose Joaquin de Olmedo Intl. (GYE), Tocumen Intl. (PTY), and Jorge Chavez Intl. (LIM).
What is the earliest flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The earliest flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) typically departs around 12:00 AM local time. This service is operated by LATAM Airlines Group and is a seasonal offering, active only in April. An early departure like this can be great for maximizing your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
You'll generally find the most flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) on a Wednesday, with around 22 flights available. This gives you a good selection for your travel plans. Major airlines on this route include LATAM Airlines Group, Avianca, and Copa. Looking at the week, Wednesday offers notably more flight options compared to other days, ensuring you have plenty of choices.
What are the most popular departure times for flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
The most popular departure times for flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) are in the evening, from 6pm to 9pm. Many major carriers, including Copa, LATAM Airlines Group and Avianca, offer flights during this window. Many travellers prefer this time as it allows you to finish your day in Quito and arrive in Santiago later in the evening.
How long does it take to fly from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
There are no nonstop flights from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez). The distance between these two cities is approximately 3783 kilometres. Flights with one stop typically take around 16 hours 30 minutes. If you opt for flights with two or more stops, your travel time will be longer, usually around 24 hours 30 minutes. Keep in mind that actual flight times can vary due to factors like routing, weather, and wind patterns.
Can you fly business or first class from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez)?
Yes, you can fly business class between UIO and SCL. Airlines that offer business class service on this route include:
  • Copa
  • Avianca
  • United
How do I earn miles on a Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?
It's easy to earn miles on a Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Santiago (SCL) from Quito (UIO)?
If you're planning to travel to Santiago from Mariscal Sucre Intl. (UIO), you can fly directly into Arturo Merino Benitez (SCL). Some flights may connect through major hubs like Jose Joaquin de Olmedo Intl. (GYE), Jorge Chavez Intl. (LIM), or El Dorado Intl. (BOG) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) at the last minute?
Typically, booking a last minute flight from Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?
Securing a Quito (UIO-Mariscal Sucre Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Quito (UIO) to Santiago (SCL)?
If you booked your Quito (UIO) to Santiago (SCL) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mariscal Sucre Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
LATAM Airlines Group, avianca
Roundtrip price
CA $707
Distance
3761 km

Book with confidence

Quito to Santiago Flights

The easy way to book your flights from Quito to Santiago 

With Expedia, it’s simple to find and book flights to Santiago from Quito whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Arturo Merino Benitez, too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Quito to Santiago today, tomorrow, or this week.  

 

Save dollars with cheap flights from Mariscal Sucre Intl., UIO to Arturo Merino Benitez, SCL 

Sort your search results by price to find great deals on your flight from Quito to Santiago—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Santiago from Quito currently is just CA $707 rising to CA $783.  

Here are more money-saving tips: 

  • Fly in October when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Santiago  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Santiago from Quito 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Santiago with Expedia today.

Quito to Santiago Flights

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*Available to Expedia members.