Cheap flights from Mexico City to Southeast Region from CA $306

View CA $306 flight on Thu, Dec. 4, 2025Opens in a new window

Popular airlines from Mexico City to Southeast Region

  • Avianca

    Avianca

  • LATAM Airlines Group

    LATAM Airlines Group

  • Aeromexico

    Aeromexico

  • GOL Linhas Aereas S.A.

    GOL Linhas Aereas S.A.

  • Air Canada

    Air Canada

  • Aerolineas Argentinas

    Aerolineas Argentinas

  • American Airlines

    American Airlines

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Cheap flights from Mexico City (MEX) to Southeast Region (RIO)

Prices were available within the past 7 days and start at CA $306 for one-way flights and CA $569 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Arajet
Thu, Oct. 23 - Wed, Oct. 29
NLU
Mexico City
GRU
Sao Paulo
CA $569 Roundtrip, found 4 days ago
CA $569
Roundtrip
found 4 days ago
Select Arajet flight, departing Thu, Oct. 23 from Mexico City to Sao Paulo, returning Wed, Oct. 29, priced at CA $569 found 4 days ago
Aeromexico
Mon, Nov. 10 - Tue, Nov. 18
MEX
Mexico City
GRU
Sao Paulo
CA $710 Roundtrip, found 6 days ago
CA $710
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Mon, Nov. 10 from Mexico City to Sao Paulo, returning Tue, Nov. 18, priced at CA $710 found 6 days ago
Copa
Tue, Aug. 26 - Thu, Sep. 4
MEX
Mexico City
GIG
Rio de Janeiro
CA $750 Roundtrip, found 6 days ago
CA $750
Roundtrip
found 6 days ago
Select Copa flight, departing Tue, Aug. 26 from Mexico City to Rio de Janeiro, returning Thu, Sep. 4, priced at CA $750 found 6 days ago
LATAM Airlines Group
Mon, Nov. 10 - Tue, Nov. 18
MEX
Mexico City
GRU
Sao Paulo
CA $753 Roundtrip, found 6 days ago
CA $753
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Mon, Nov. 10 from Mexico City to Sao Paulo, returning Tue, Nov. 18, priced at CA $753 found 6 days ago
avianca
Sun, Aug. 31 - Mon, Sep. 8
MEX
Mexico City
GRU
Sao Paulo
CA $768 Roundtrip, found 5 hours ago
CA $768
Roundtrip
found 5 hours ago
Select avianca flight, departing Sun, Aug. 31 from Mexico City to Sao Paulo, returning Mon, Sep. 8, priced at CA $768 found 5 hours ago
LATAM Airlines Group
Mon, Aug. 25 - Tue, Aug. 26
MEX
Mexico City
SDU
Rio de Janeiro
CA $775 Roundtrip, found 6 days ago
CA $775
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Mon, Aug. 25 from Mexico City to Rio de Janeiro, returning Tue, Aug. 26, priced at CA $775 found 6 days ago

Find the cheapest month to fly from Mexico City (MEX) to São Paulo (GRU)

October is typically the cheapest month to fly

From CA $460 - CA $797 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.