Cheap flights from Denver to South San Diego from CA $108

View CA $108 flight on Sun, Aug. 17, 2025Opens in a new window

Popular airlines from Denver to South San Diego

  • Air Canada

    Air Canada

  • WestJet

    WestJet

  • Flair Airlines

    Flair Airlines

  • American Airlines

    American Airlines

  • United

    United

  • Delta

    Delta

  • Porter Airlines

    Porter Airlines

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Denver (DEN) to South San Diego (SAN)

Prices were available within the past 7 days and start at CA $108 for one-way flights and CA $200 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hawaiian Airlines
Sat, Oct. 4 - Sun, Oct. 5
DEN
Denver
SAN
San Diego
CA $200 Roundtrip, found 6 days ago
CA $200
Roundtrip
found 6 days ago
Select Hawaiian Airlines flight, departing Sat, Oct. 4 from Denver to San Diego, returning Sun, Oct. 5, priced at CA $200 found 6 days ago
Alaska Airlines
Sun, Oct. 5 - Mon, Oct. 6
DEN
Denver
SAN
San Diego
CA $214 Roundtrip, found 6 days ago
CA $214
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Sun, Oct. 5 from Denver to San Diego, returning Mon, Oct. 6, priced at CA $214 found 6 days ago
American Airlines
Wed, Oct. 1 - Mon, Oct. 6
DEN
Denver
CLD
Carlsbad
CA $217 Roundtrip, found 6 days ago
CA $217
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Oct. 1 from Denver to Carlsbad, returning Mon, Oct. 6, priced at CA $217 found 6 days ago
American Airlines
Wed, Oct. 1 - Mon, Oct. 6
DEN
Denver
SAN
San Diego
CA $217 Roundtrip, found 6 days ago
CA $217
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Oct. 1 from Denver to San Diego, returning Mon, Oct. 6, priced at CA $217 found 6 days ago
Delta
Thu, Oct. 2 - Sun, Oct. 5
DEN
Denver
SAN
San Diego
CA $257 Roundtrip, found 6 days ago
CA $257
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Oct. 2 from Denver to San Diego, returning Sun, Oct. 5, priced at CA $257 found 6 days ago
United
Wed, Oct. 1 - Mon, Oct. 6
DEN
Denver
SAN
San Diego
CA $264 Roundtrip, found 6 days ago
CA $264
Roundtrip
found 6 days ago
Select United flight, departing Wed, Oct. 1 from Denver to San Diego, returning Mon, Oct. 6, priced at CA $264 found 6 days ago
*Available to Expedia members.