Cheap flights from Guayaquil to Andean Natural Region from CA $269

View CA $269 flight on Fri, Sep. 26, 2025Opens in a new window

Popular airlines from Guayaquil to Andean Natural Region

  • Avianca

    Avianca

  • LATAM Airlines Group

    LATAM Airlines Group

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Cheap flights from Guayaquil (GYE) to Andean Natural Region (MDE)

Prices were available within the past 7 days and start at CA $269 for one-way flights and CA $582 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Mon, Aug. 4 - Wed, Aug. 13
GYE
Guayaquil
MDE
Medellin
CA $582 Roundtrip, found 5 days ago
CA $582
Roundtrip
found 5 days ago
Select avianca flight, departing Mon, Aug. 4 from Guayaquil to Medellin, returning Wed, Aug. 13, priced at CA $582 found 5 days ago
avianca
Sat, Aug. 2 - Wed, Aug. 13
GYE
Guayaquil
MDE
Medellin
CA $606 Roundtrip, found 5 days ago
CA $606
Roundtrip
found 5 days ago
Select avianca flight, departing Sat, Aug. 2 from Guayaquil to Medellin, returning Wed, Aug. 13, priced at CA $606 found 5 days ago
avianca
Mon, Aug. 4 - Sat, Aug. 9
GYE
Guayaquil
MDE
Medellin
CA $606 Roundtrip, found 5 days ago
CA $606
Roundtrip
found 5 days ago
Select avianca flight, departing Mon, Aug. 4 from Guayaquil to Medellin, returning Sat, Aug. 9, priced at CA $606 found 5 days ago
Copa
Wed, Aug. 6 - Thu, Aug. 14
GYE
Guayaquil
MDE
Medellin
CA $613 Roundtrip, found 5 days ago
CA $613
Roundtrip
found 5 days ago
Select Copa flight, departing Wed, Aug. 6 from Guayaquil to Medellin, returning Thu, Aug. 14, priced at CA $613 found 5 days ago
avianca
Sat, Aug. 2 - Sat, Aug. 9
GYE
Guayaquil
MDE
Medellin
CA $631 Roundtrip, found 5 days ago
CA $631
Roundtrip
found 5 days ago
Select avianca flight, departing Sat, Aug. 2 from Guayaquil to Medellin, returning Sat, Aug. 9, priced at CA $631 found 5 days ago
LATAM Airlines Group
Mon, Oct. 13 - Tue, Oct. 14
GYE
Guayaquil
MDE
Medellin
CA $632 Roundtrip, found 4 days ago
CA $632
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, Oct. 13 from Guayaquil to Medellin, returning Tue, Oct. 14, priced at CA $632 found 4 days ago

Find the cheapest month to fly from Guayaquil (GYE) to Bogotá (BOG)

September is typically the cheapest month to fly

From CA $294 - CA $607 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.