Downtown
Seneca
Visit Downtown
Stay near popular Downtown attractions
Downtown Hotel Deals
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundable
The price is CA $110 per night from Jul 26 to Jul 27
CA $110
CA $134 total
Jul 26 - Jul 27
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
The price is CA $86 per night from Aug 18 to Aug 19
CA $86
CA $95 total
Aug 18 - Aug 19
includes taxes & fees
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very good! (1,008 reviews)
"I chose this because it was rated as at least an 8 (very good) on the app. The property and room was more like a 5-6. Room was ok, but had a lot of wear and tear, broken but operable toilet, all a bit more grimy than an "8" would lead me to expect."
Reviewed on Jul 19, 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
The price is CA $148 per night from Jul 27 to Jul 28
CA $148
CA $165 total
Jul 27 - Jul 28
includes taxes & fees
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8.2/10 Very good! (1,010 reviews)
"One room smell pretty moldy so we got another room but other than that it was a good stay. The staff was very attentive thank you very much."
Reviewed on Jul 21, 2026
The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
The price is CA $219 per night from Jul 27 to Jul 28
CA $219
CA $243 total
Jul 27 - Jul 28
includes taxes & fees
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
The price is CA $153 per night from Jul 24 to Jul 25
CA $153
CA $190 total
Jul 24 - Jul 25
includes taxes & fees
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,004 reviews)
"Lakeside Lodge is my favorite place for a quick weekend getaway & it never disappoints. We enjoyed our stay this past weekend and had a great Saturday at the pool. I look forward to our next visit."
Reviewed on Jul 20, 2026
Courtyard Marriott Clemson
201 Canoy Ln Clemson SC
The price is CA $190 per night from Aug 9 to Aug 10
CA $190
CA $211 total
Aug 9 - Aug 10
includes taxes & fees
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Memorial Stadium and Clemson ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Learn more about Downtown
Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Pine Ridge Point
While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.
Indian Oaks
While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Keowee Reservoir.
Keowee Plantation
When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Keowee Reservoir, some noteworthy sights in the nearby area.
Downtown
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