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Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Nov 13 - Nov 15
In two months
Dec 25 - Dec 27
In three months
Jan 22 - Jan 24
In four months
Feb 19 - Feb 21

Our top choices for Santa Cruz vacation rentals

A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

1. A08 SUPER CITY SUITES AT PLAZA ACEQUIA

A08 SUPER CITY SUITES AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
8.0 out of 10, Very good, (4 reviews)
"No dejan dormir pasaron algunos huéspedes ablandó fuerte y caminando por los corredores y nadie les llamó la atención. Según parecía estaban borrachos"
United States
Mario
The price is CA $77
CA $119 total
includes taxes & fees
Nov 9 - Nov 10
A08 SUPER CITY SUITES AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

2. A25 Full Suite MiniDept at Plaza Acequia

A25 Full Suite MiniDept at Plaza Acequia
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
The price is CA $71
CA $138 total
includes taxes & fees
Nov 29 - Nov 30
A25 Full Suite MiniDept at Plaza Acequia
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

3. A30 Plaza Acequia Suite Black Plus

A30 Plaza Acequia Suite Black Plus
3.5 star property
Cuautitlán Izcalli
10.0 out of 10, Exceptional, (1 review)
"Todo un ambiente acogedor"
Mexico
GENER KEINER
The price is CA $90
CA $135 total
includes taxes & fees
Nov 5 - Nov 6
A30 Plaza Acequia Suite Black Plus
Interior entrance

4. Moderna, Cómoda Suite Nube en Tepotzotlán centro

Moderna, Cómoda Suite Nube en Tepotzotlán centro
4.0 star property
Tepotzotlán
9.6 out of 10, Exceptional, (9 reviews)
"Increíble!! Una habitación pequeña pero perfecta, muy cómoda, muy linda, daban ganas de quedarse más tiempo! Muy recomendable. Vale totalmente la pena"
Mexico
Eduardo
The price is CA $72
CA $87 total
includes taxes & fees
Nov 18 - Nov 19
Moderna, Cómoda Suite Nube en Tepotzotlán centro
A compact kitchen with a built-in microwave, a gas stove, and a dishwasher.

5. Moderna, Comoda Suite Palma en Tepotzotlán centro

Moderna, Comoda Suite Palma en Tepotzotlán centro
3.0 star property
Tepotzotlán
10.0 out of 10, Exceptional, (3 reviews)
"Friendly host who was very helpful in recommending things to do and places to eat. Located just a few blocks from the historical district. On your way there, you'll pass wonderful restaurants, coffee shops, gyms, and convient stores. This place is in a great location and having garage parking was a real plus. Absolutely a beautiful room and very clean. I was very impressed and highly recommend staying here."
United States
Nathan
The price is CA $87
CA $104 total
includes taxes & fees
Nov 9 - Nov 10
Moderna, Comoda Suite Palma en Tepotzotlán centro
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

6. A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA

A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (8 reviews)
"Buena la estancia "
Mexico
Héctor
The price is CA $77
CA $119 total
includes taxes & fees
Nov 11 - Nov 12
A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

7. A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Lo único que me disgusta es que no hay agua caliente )): Pero sin duda iré todos los 12 de cada mes "
Mexico
Jeik
The price is CA $77
CA $119 total
includes taxes & fees
Nov 22 - Nov 23
A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

8. A07 SUPER CITY SUITES AT PLAZA ACEQUIA

A07 SUPER CITY SUITES AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Buen lugar tranquilo "
Mexico
Valeria
The price is CA $80
CA $96 total
includes taxes & fees
Nov 7 - Nov 8
A07 SUPER CITY SUITES AT PLAZA ACEQUIA
A balcony with two chairs, a small table with a book and a cup, and a view of the cityscape.

9. S06 PREMIUM SUITE Full Service WiFi Kitc

S06 PREMIUM SUITE Full Service WiFi Kitc
3.5 star property
Ciudad López Mateos
9.8 out of 10, Exceptional, (6 reviews)
"Estuvo super bien nuestra estancia "
Mexico
Sophie
The price is CA $72
CA $113 total
includes taxes & fees
Nov 16 - Nov 17
S06 PREMIUM SUITE Full Service WiFi Kitc
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

10. A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (3 reviews)
"Buenas instalaciones y ubicación para mis desplazamientos"
Mexico
ANGEL
The price is CA $77
CA $119 total
includes taxes & fees
Nov 9 - Nov 10
A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

11. A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
The price is CA $69
CA $109 total
includes taxes & fees
Nov 28 - Nov 29
A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

12. A10 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A10 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (6 reviews)
"Muy buena experiencia, todo muy claro y es diferente a lo convencional, tal vez digan que por el precio serán instalaciones no muy agradables, pero en verdad hay sorpresas recomendado ampliamente, la persona encargada de cuidar es muy amable y atento!!! "
Mexico
Jorge
The price is CA $77
CA $119 total
includes taxes & fees
Nov 29 - Nov 30
A10 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A hotel entrance with a modern design, featuring a glass door and a sign with multilingual greetings.

13. A03 SUPER CITY SUITE AT PLAZA ACEQUIA

A03 SUPER CITY SUITE AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
The price is CA $71
CA $147 total
includes taxes & fees
Nov 29 - Nov 30
A03 SUPER CITY SUITE AT PLAZA ACEQUIA
A palm tree in front of a building with arched windows and a brick facade.

14. cabañas en arcos del sitio

cabañas en arcos del sitio
3.0 star property
Nicolás Romero
The price is CA $167
CA $240 total
includes taxes & fees
Nov 1 - Nov 2
cabañas en arcos del sitio
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

15. A13 SUPER CITY SUITE PLAZA ACEQUIA

A13 SUPER CITY SUITE PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
"Buen servicio "
Mexico
Ruben
The price is CA $77
CA $118 total
includes taxes & fees
Nov 30 - Dec 1
A13 SUPER CITY SUITE PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

16. A24 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A24 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
The price is CA $72
CA $113 total
includes taxes & fees
Nov 4 - Nov 5
A24 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
Balcony

17. S09 PREMIUM SUITE Full Service WiFi

S09 PREMIUM SUITE Full Service WiFi
3.5 star property
Ciudad López Mateos
9.6 out of 10, Exceptional, (4 reviews)
"Excelente"
United States
Yulissa Rubi
The price is CA $72
CA $113 total
includes taxes & fees
Nov 11 - Nov 12
S09 PREMIUM SUITE Full Service WiFi
A compact kitchen with a wooden cabinet, a sink, and a countertop. There are kitchen utensils and a coffee maker on the counter.

18. S02 FULL SUITE ITESM CEM WiFi Terraza

S02 FULL SUITE ITESM CEM WiFi Terraza
3.5 star property
Ciudad López Mateos
10.0 out of 10, Exceptional, (1 review)
"Muy limpio Agradable la señorita de limpieza"
Mexico
Mauricio
The price is CA $78
CA $93 total
includes taxes & fees
Nov 15 - Nov 16
S02 FULL SUITE ITESM CEM WiFi Terraza
A modern bedroom with a large bed, a nightstand, a desk, and a view through large windows.

19. S10 PREMIUM SUITE Full Service WiFi

S10 PREMIUM SUITE Full Service WiFi
3.5 star property
Ciudad López Mateos
8.0 out of 10, Very good, (1 review)
"Habitacion limpia"
Mexico
Yolanda Sandoval
The price is CA $72
CA $113 total
includes taxes & fees
Nov 23 - Nov 24
S10 PREMIUM SUITE Full Service WiFi
A balcony with a blue chair, a table with a book, a water bottle, and a potted plant.

20. S08 PREMIUM SUITE Full Service WiFi

S08 PREMIUM SUITE Full Service WiFi
3.5 star property
Ciudad López Mateos
The price is CA $67
CA $107 total
includes taxes & fees
Nov 19 - Nov 20
S08 PREMIUM SUITE Full Service WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel Parque Satelite

Hotel Parque Satelite

10/10 Excellent
"Todo marcha bien, buen servicio sobre todo del Capitán del Restaurante llamado Arturo"
Ignacio 1-night trip
Posted 2 days ago
Hotel Parque Satelite

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz vacation rentals we have selected for you start as low as CA $64 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there vacation rentals in Santa Cruz?

Yes, you can find vacation rentals near popular points of interest in Santa Cruz, or you can go with a secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

Luxe Polanco Home Private Yard and Private Patio: This vacation home rental near Santa Cruz offers a garden, a selection of games, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Parque Acuatico Vito Spa, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties you can book for a long or short time in Santa Cruz. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family trips.