Name: Hyatt Regency Mexico City
Price range: CA $383
Rating: 9.4

Your Santa Cruz Vacation

Say bye-bye to the worries of planning and hello to a Santa Cruz vacation package. With your travel details organized before you go, you can focus on discovering the best of this city, starting with Tlalnepantla Centro, which is great for bars and pubs, shopping and dining. If taking in the sights is a priority during your trip to Santa Cruz, make sure you find your way to well-known attractions like Xochitla Ecological Park and Temple of San Francisco Javier. Whoever you're taking time off with and whatever the size of your budget, your dream Santa Cruz vacation is just a few clicks away with Expedia.

Top Santa Cruz Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Hotel & Suites PF

Reforma

CA $696

per person

Aug 10 - Aug 17

found 1 day ago

Roundtrip flight included

Vancouver (YVR) to Mexico City (MEX)

8.6/10 Excellent! (2,304 reviews)

Súper limpio y el personal amable

Reviewed on Apr 28, 2026

Casa Decu

La Condesa

CA $1,460

per person

Jul 10 - Jul 17

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to Mexico City (MEX)

9.4/10 Exceptional! (926 reviews)

A bottle of wine in my room to greet me. Amazing staff who were so helpful. Could not ask for much more

Reviewed on May 24, 2026

Hacienda Peña Pobre

Tlalpan

CA $960

per person

Jul 29 - Aug 4

found 1 day ago

Roundtrip flight included

Toronto (YTO) to Mexico City (MEX)

9.6/10 Exceptional! (763 reviews)

Excellent hotel, the property is beautiful, with gardens and hacienda- type construction. The room is very ample and comfortable, the bed is great as are the pillows, the hot water comes on immediately, the staff is very nice and helpful. Would definitely stay here again!

Reviewed on May 21, 2026

Marquis Sky Suites

Reforma

CA $2,636

per person

Jul 1 - Jul 6

found 1 day ago

Roundtrip flight included

Toronto (YTO) to Mexico City (MEX)

8.8/10 Excellent! (33 reviews)

I love !!Gran Marquis hotel in Mexico City this my 8 or 9 time and I will be back ,the sky suites are clean and nice ,the only issue this time it’s was a lot of noise from the next door neighbors there were so loud around 1:00 in the morning

Reviewed on May 4, 2026

Gran Hotel Ciudad de Mexico Zocalo View

Historic Center

CA $1,675

per person

Jul 10 - Jul 17

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to Mexico City (MEX)

9.6/10 Exceptional! (1,185 reviews)

Great hotel but be aware that vehicular access is quite difficult-usually a block’s walk and the area is a bit sketchy after dark. Breakfast on the terrace is excellent.

Reviewed on May 22, 2026

Ready to book your vacation to Santa Cruz?

Choose your dates

Santa Cruz Hotel Deals

InterContinental Presidente Mexico City by IHG

Campos Eliseos 218 Mexico City

CA $504

CA $603 total

May 30 - May 31

includes taxes & fees

9.4/10 Exceptional! (2,394 reviews)

"El hotel Presidente intercontinental nunca decepciona. Magnifico hotel. Una Att espectacular por parte de sus empleados."

Reviewed on May 25, 2026

Downtown Treasure Place

85 Marte Guerrero Mexico City CDMX

Fully refundableReserve now, pay when you stay

CA $53

CA $64 total

May 26 - May 27

includes taxes & fees

8.8/10 Excellent! (825 reviews)

"Bed sheets very dirty, no wifi, no intimacy, loud music playing early in the morning, room very dirty, no room service during my 3 night stay. I arrived late to this place and had to wait outside for one hour since no one was answering the door nor the phone despite me letting them in advance that ..."

Reviewed on Mar 31, 2026

Hyatt Regency Mexico City

Campos Eliseos No. 204 Polanco Mexico City

Fully refundableReserve now, pay when you stay

CA $383

CA $457 total

Jun 12 - Jun 13

includes taxes & fees

9.4/10 Exceptional! (1,445 reviews)

"Excellent hotel and location. Gym and pool were excellent."

Reviewed on May 15, 2026

See all 1,665 properties in Santa Cruz

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.