Santa Cruz Vacation Packages

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  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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    Plan, book, and manage your trip all in one place

Your Santa Cruz Vacation

Say bye-bye to the worries of planning and hello to a Santa Cruz vacation package. With your travel details organized before you go, you can focus on discovering the best of this city, starting with Tlalnepantla Centro, which is great for bars and pubs, shopping and dining. If taking in the sights is a priority during your trip to Santa Cruz, make sure you find your way to well-known attractions like Xochitla Ecological Park and Temple of San Francisco Javier. Whoever you're taking time off with and whatever the size of your budget, your dream Santa Cruz vacation is just a few clicks away with Expedia.

Top Santa Cruz Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Casa Decu

Casa Decu

La Condesa
Save 100% on your flight
CA $948
per person
Dec 3 - Dec 9
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Mexico City (MEX)
9.4/10 Exceptional! (1,007 reviews)
Beautiful spot in the heart of Condesa! Perfect spot, close to restaurants, sites and completely walkable. Great amenities, spacious rooms and the breakfast is a nice touch. Very nice people, can't go wrong!

Reviewed on Oct 11, 2026

Hacienda Peña Pobre

Hacienda Peña Pobre

Tlalpan
Save 100% on your flight
CA $1,285
per person
Nov 22 - Nov 29
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Mexico City (MEX)
9.6/10 Exceptional! (890 reviews)
The Hacienda Pena Pobre is a beautiful and relaxing please to stay in Mexico City. The rooms are spacious and extremely clean. The staff extremely professional and friendly. I will stay there again soon.

Reviewed on Oct 9, 2026

Colima 71 Casa de Arte Hotel

Colima 71 Casa de Arte Hotel

Roma Norte
CA $3,830
per person
Nov 30 - Dec 7
found 21 hours ago
Roundtrip flight included
Vancouver (YVR) to Mexico City (MEX)
9.8/10 Exceptional! (53 reviews)
Superb. One of the best (if not the best) boutique hotels I’ve ever stayed in. All the space is exquisitely designed. The food is glorious but it’s the staff what makes it absolutely outstanding. Yes you can stay in so many other different small, boutique, design-forward hotels in CDMX, but know, you’ll be missing out.

Reviewed on Sep 13, 2026

Hotel Luca

Hotel Luca

Roma Norte
Save 100% on your flight
CA $1,874
per person
Nov 30 - Dec 7
found 22 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Mexico City (MEX)
9.2/10 Wonderful! (430 reviews)
ULIV Park Polanco

ULIV Park Polanco

Polanco
Save 100% on your flight
CA $1,802
per person
Nov 22 - Nov 29
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Mexico City (MEX)
9.4/10 Exceptional! (139 reviews)
The property is in a great location. The doorman/security person was always available. The rooms are modern and clean.

Reviewed on Oct 4, 2026

Ready to book your vacation to Santa Cruz?

Choose your dates

Santa Cruz Hotel Deals

InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG

Campos Eliseos 218 Mexico City
Fully refundable
CA $689
CA $823 total
Oct 24 - Oct 25
includes taxes & fees
9.4/10 Exceptional! (2,475 reviews)
"Excellent welcome and during our stay. Staff always friendly and helpful"

Reviewed on Oct 12, 2026

InterContinental Presidente Mexico City by IHG
Casa Olea

Casa Olea

C. de Francisco Díaz Covarrubias Mexico City CDMX
Fully refundableReserve now, pay when you stay
CA $72
CA $86 total
Nov 11 - Nov 12
includes taxes & fees
9.4/10 Exceptional! (983 reviews)
"Such a beautiful hotel! Always so clean, the staff is so nice, the coffee shop and tiendita downstairs is a plus. The hotel itself is so cute and the rooms are so nice. Will definitely be staying here again when i go back to CDMX. Muchas Gracias Casa Olea!"

Reviewed on Oct 10, 2026

Casa Olea
Hyatt Regency Mexico City

Hyatt Regency Mexico City

Campos Eliseos No. 204 Polanco Mexico City
Fully refundableReserve now, pay when you stay
CA $455
CA $543 total
Oct 17 - Oct 18
includes taxes & fees
Hyatt Regency Mexico City
See all 1,600 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations
Golf Vacations
Golf Vacations
Luxury Vacations
Luxury Vacations
Romantic Vacations
Romantic Vacations
Ski Vacations
Ski Vacations

What to do in Santa Cruz

Immerse in the Nature: Deep Connection through Forest Bathing

Immerse in the Nature: Deep Connection through Forest Bathing

CA $114
per adult
Immerse in the Nature: Deep Connection through Forest Bathing
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Offering excellent value package deals from CA $948 on Expedia, you'll be thrilled with how little a vacation to Santa Cruz costs! Expedia's packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Cruz?
You're likely to find lower prices and greater availability in January, February and June. Check out our cheap Santa Cruz vacation packages and you could score some great off-season deals.
How many days is enough for Santa Cruz?
You can easily explore all the top attractions in Santa Cruz within a few days, including the must-see Temple of San Francisco Javier. If you're after a longer Santa Cruz vacation, check out what sort of activities and day tours are available close by.
How to find the best Santa Cruz package deals?
Use Expedia's filters to find some great Santa Cruz package deals. When you begin your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or browse for Santa Cruz package deals in the off-peak season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz vacation as a package?
You can enjoy significant savings on your next Santa Cruz break by booking a customized vacation package. Click on the "Package" heading, then select your destination and travel dates to see the best flight and hotel prices. Bundling can save travellers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Cruz?
Secure incredible bargains by reserving your flights ahead of time with Expedia. If being spontaneous is more your style, snap up one of our last-minute deals for an impromptu Santa Cruz break.
How to plan a trip to Santa Cruz?
  1. Choose when to go: Check your calendar and get packing. Your favourite season and the activities on offer will also help you decide when to vacation in Santa Cruz.
  2. Plan your budget wisely: As well as the cost of your accommodations, you'll need to factor in other expenses too. These include transportation, food and flights. Also, put aside some extra funds for unexpected expenses that could arise during your trip to Santa Cruz.
  3. Work out your trip length: Consider how much time you'd like to spend exploring Santa Cruz. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
  4. Bundle your flights and hotel: Epic destination, check. Length of stay, check. Now all that's left is to choose a Santa Cruz vacation package that brings all your bookings together.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.