Title: 10 Best Hotels in Santa Cruz, Cuiabá for 2025 | Expedia.ca [Vacation Rentals in Cuiabá](https://expedia.ca/Cuiaba-Vacation-Rentals.d818.Travel-Guide-VacationRentals)[Flights to Cuiabá](https://expedia.ca/Cheap-Flights-To-Cuiaba.d818.Travel-Guide-Flights)[Santa Cruz Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz.d553248635318496020.Car-Rental-Guide)[Santa Cruz Vacations](https://expedia.ca/Santa-Cruz.d553248635318496020.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Santa Cruz, Cuiabá - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Cruz Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Cuiab%C3%A1%2C+Mato+Grosso%2C+Brazil®ionId=553248635318496020&latLong=-15.607775%2C-56.046149&adults=2&startDate=2025-12-02&d1=2025-12-02&endDate=2025-12-04&d2=2025-12-04&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Cuiab%C3%A1%2C+Mato+Grosso%2C+Brazil®ionId=553248635318496020&latLong=-15.607775%2C-56.046149&adults=2&startDate=2025-12-02&d1=2025-12-02&endDate=2025-12-04&d2=2025-12-04&amenities=POOL) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Cuiab%C3%A1%2C+Mato+Grosso%2C+Brazil®ionId=553248635318496020&latLong=-15.607775%2C-56.046149&adults=2&startDate=2025-12-02&d1=2025-12-02&endDate=2025-12-04&d2=2025-12-04&lodging=APARTMENT) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Cruz%2C+Cuiab%C3%A1%2C+Mato+Grosso%2C+Brazil®ionId=553248635318496020&latLong=-15.607775%2C-56.046149&adults=2&startDate=2025-12-02&d1=2025-12-02&endDate=2025-12-04&d2=2025-12-04&amenities=PETS) ## Check prices for these dates Tonight [Nov 18 - Nov 19](https://www.expedia.ca/Hotel-Search?regionId=553248635318496020&startDate=2025-11-18&endDate=2025-11-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 19 - Nov 20](https://www.expedia.ca/Hotel-Search?regionId=553248635318496020&startDate=2025-11-19&endDate=2025-11-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635318496020&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635318496020&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Santa Cruz hotels and places to stay ![Reception](https://images.trvl-media.com/lodging/9000000/8780000/8777200/8777102/da91b00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8780000/8777200/8777102/7a432d1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8780000/8777200/8777102/7ba438a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Brazilian cuisine ](https://images.trvl-media.com/lodging/9000000/8780000/8777200/8777102/00ab39ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Delmond Hotel Alvorada, 5.2 km from Santa Cruz 9.0/10 Wonderful (733) "Great hotel to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Agenor CA $80 CA $90 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Cuiaba-Hotels-Delmond-Hotel.h8777102.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/58000000/57520000/57516200/57516156/5cbdcfd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Double Bed](https://images.trvl-media.com/lodging/58000000/57520000/57516200/57516156/3992ff37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/58000000/57520000/57516200/57516156/9aaec450.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/58000000/57520000/57516200/57516156/4f76f854.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ibis Cuiabá Jardim Cuiabá, 7.9 km from Santa Cruz 8.2/10 Very good (232) "Otimo" ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) René CA $93 CA $96 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Cuiaba-Hotels-Ibis-Cuiaba.h57516156.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/70000000/69820000/69812300/69812203/66f54341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/70000000/69820000/69812300/69812203/2eeaac31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/70000000/69820000/69812300/69812203/1e48a6a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room](https://images.trvl-media.com/lodging/70000000/69820000/69812300/69812203/34396cf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Veneza Palace Hotel Bandeirantes, 4.7 km from Santa Cruz 8.2/10 Very good (405) "Bom hotel." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) AUGUSTO [](https://www.expedia.ca/Cuiaba-Hotels-VENEZA-PALACE-HOTEL.h69812203.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6610000/6603500/6603464/b0109d6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Triple Room](https://images.trvl-media.com/lodging/7000000/6610000/6603500/6603464/c07177f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/7000000/6610000/6603500/6603464/2ae32bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/7000000/6610000/6603500/6603464/c5e6342f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HITS PANTANAL HOTEL AEROPORTO 9.7 km from Santa Cruz 8.4/10 Very good (401) "A nice hotel, friendly staff, adjacent to a shopping mall, close to the airport but very quiet, a very efficient transfer service to to pick me up from the airport. But what really stands out is the amazing swimming pool. One of the best pools I encountered at a hotel for swimming laps! I can definately recommend this hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rob CA $65 CA $69 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Cuiaba-Hotels-Hits-Pantanal-Hotel.h6603464.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/6000000/5560000/5558400/5558354/cde1b85d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5560000/5558400/5558354/5f99dd59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Triple Room](https://images.trvl-media.com/lodging/6000000/5560000/5558400/5558354/3b017ee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/6000000/5560000/5558400/5558354/4c2b849b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel D'luca 5.2 km from Santa Cruz 9.4/10 Exceptional (526) "Excelente hotel!" ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Alex CA $88 CA $91 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Cuiaba-Hotels-Hotel-Dluca.h5558354.Hotel-Information) ![Outdoor pool, open 6:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/11000000/10560000/10553600/10553530/4b7aeaeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/11000000/10560000/10553600/10553530/21fedffc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10560000/10553600/10553530/f637c4a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/11000000/10560000/10553600/10553530/62aded0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Paiaguás Palace Hotel Bosque da Saúde, 4.4 km from Santa Cruz 8.4/10 Very good (356) "Bom hotel" ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Roseli CA $87 CA $90 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Cuiaba-Hotels-Paiaguas-Palace-Hotel.h10553530.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3980000/3972600/3972533/2bece742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3980000/3972600/3972533/c1503839.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/4000000/3980000/3972600/3972533/3dc3991e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3980000/3972600/3972533/0f6d8035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amazon Plaza Hotel Central North, 5.8 km from Santa Cruz 8.6/10 Excellent (509) "Nice hotel with good service and breakfast. Well located" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angelica CA $104 CA $107 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Cuiaba-Hotels-Amazon-Plaza-Hotel.h3972533.Hotel-Information) ![Airport shuttle](https://images.trvl-media.com/lodging/110000000/109140000/109138100/109138010/7a1ab25e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/110000000/109140000/109138100/109138010/07ccd112.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/110000000/109140000/109138100/109138010/ea57b15d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/110000000/109140000/109138100/109138010/w828h621x0y4-3b4ad8bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Itamaraty 18.8 km from Santa Cruz 8.4/10 Very good (19) "It is a very old fashioned hotel . It’s smells bad . Terrible bathroom and it stinks vey badly. Bed was not made for 4 people. Sheets was used before. Toiletries was very limited. Breakfast was good - but kitchen conditions was not good . In general I do not recommend this hotel at all . " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Luciene CA $46 CA $48 total includes taxes & fees Nov 22 - Nov 23 [](https://www.expedia.ca/Varzea-Grande-Hotels-Hotel-Itamaraty.h109138010.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/43000000/42320000/42318700/42318656/b06f988d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42320000/42318700/42318656/2c2163aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double or Twin Room](https://images.trvl-media.com/lodging/43000000/42320000/42318700/42318656/ce759afa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/43000000/42320000/42318700/42318656/3d8af74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Advanced Hotel e Flats Duque de Caxias, 7.9 km from Santa Cruz 9.0/10 Wonderful (130) "Excelente a estadia." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Edson [](https://www.expedia.ca/Cuiaba-Hotels-Advanced-Business-E-Flats-Hotel.h42318656.Hotel-Information) ![Outdoor pool, open 10 AM to midnight, sun loungers](https://images.trvl-media.com/lodging/7000000/6520000/6516100/6516031/b4d30829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6520000/6516100/6516031/042254a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/7000000/6520000/6516100/6516031/448c72ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/7000000/6520000/6516100/6516031/86b908bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel 365 4.6 km from Santa Cruz 8.0/10 Very good (92) "Staff was very very friendly, Breakfast was good, would recommend and will stay here again when I travel to Cuiaba in the future." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Prince Sebastian Ragland CA $58 CA $66 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Cuiaba-Hotels-Hotel-Presidencial.h6516031.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/7000000/6600000/6590100/6590034/d41ac701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/7000000/6600000/6590100/6590034/813b7fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/7000000/6600000/6590100/6590034/1d9f6c01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Accessible](https://images.trvl-media.com/lodging/7000000/6600000/6590100/6590034/4aca49b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Roari Hotel 4.8 km from Santa Cruz 8.8/10 Excellent (110) "Atendimento excelente, e condições justas pelo valor." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Anonymous traveller CA $83 CA $85 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Cuiaba-Hotels-Roari-Hotel.h6590034.Hotel-Information) ![Luxury Room](https://images.trvl-media.com/lodging/5000000/4040000/4035100/4035073/4e2bc405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed](https://images.trvl-media.com/lodging/5000000/4040000/4035100/4035073/756b02e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4040000/4035100/4035073/51ec9677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4040000/4035100/4035073/0fa92054.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Inter Cuiabá Jardim das Américas, 3.4 km from Santa Cruz 9.0/10 Wonderful (348) "Beds were comfortable and the roomwas was clean and spacious. Nice quiet hotel with ease of access to many things in town. Allen at front desk was the best. Breakfast was good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen CA $109 CA $123 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Cuiaba-Hotels-Holiday-Inn-Cuiaba.h4035073.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/38000000/37200000/37198900/37198826/8f3f051a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37200000/37198900/37198826/3c7d9c42_edited_4591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/38000000/37200000/37198900/37198826/888e65b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/38000000/37200000/37198900/37198826/a3de05fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### STARLIS HOME - Versátil 6.3 km from Santa Cruz 8.4/10 Very good (77) "Boa" ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) FLAVIO CESAR CA $43 CA $80 total includes taxes & fees Nov 28 - Nov 29 [](https://www.expedia.ca/Cuiaba-Hotels-Viva-Versatil.h37198826.Hotel-Information) ![Standard Triple Room](https://images.trvl-media.com/lodging/120000000/119180000/119176400/119176353/80388e0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/120000000/119180000/119176400/119176353/93343550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/120000000/119180000/119176400/119176353/e198f090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/120000000/119180000/119176400/119176353/df92e162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Mato Grosso Inn Central North, 5.7 km from Santa Cruz 10/10 Exceptional (14) CA $72 CA $75 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Cuiaba-Hotels-Hotel-Mato-Grosso-Inn.h119176353.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26600/26534/56a71a75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | View from room](https://images.trvl-media.com/lodging/1000000/30000/26600/26534/d33500b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/1000000/30000/26600/26534/e4bc23d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26600/26534/d282faf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mato Grosso Palace Hotel Central North, 5.5 km from Santa Cruz 8.8/10 Excellent (549) "Helpful stuff and good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gwyneth [](https://www.expedia.ca/Cuiaba-Hotels-Mato-Grosso-Palace-Hotel.h26534.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/12000000/11910000/11901400/11901351/fe5be281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11910000/11901400/11901351/13d0d19d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/12000000/11910000/11901400/11901351/abd3806e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/12000000/11910000/11901400/11901351/12975a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Tainá - Aeroporto Cuiabá 9.4 km from Santa Cruz 8.2/10 Very good (394) "Clean and very near from airport." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jiro CA $74 CA $78 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Cuiaba-Hotels-Hotel-Taina-Aeroporto-Cuiaba.h11901351.Hotel-Information) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/100000000/99940000/99937700/99937689/532f6bdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Quadruple Room](https://images.trvl-media.com/lodging/100000000/99940000/99937700/99937689/7279257a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/100000000/99940000/99937700/99937689/e307a81c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99940000/99937700/99937689/aefdafce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Marion Pantanal 16.8 km from Santa Cruz 7.4/10 Good (29) "Muito o bom o quarto, cama bem confortável. Não gostei do chuveiro." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) ADRIANA CA $56 CA $62 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Varzea-Grande-Hotels-Hotel-Marion-Pantanal.h99937689.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6600000/6591100/6591093/9534664c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6600000/6591100/6591093/3d7534e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6600000/6591100/6591093/7ca72a05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LCD TV](https://images.trvl-media.com/lodging/7000000/6600000/6591100/6591093/a84b037c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Delcas Hotel Coxipó, 2.5 km from Santa Cruz 8.0/10 Very good (703) "Breakfast was amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zoe [](https://www.expedia.ca/Cuiaba-Hotels-Delcas-Hotel.h6591093.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/35000000/34180000/34178900/34178870/221e35f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/35000000/34180000/34178900/34178870/80488194.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34180000/34178900/34178870/3552c90f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34180000/34178900/34178870/7eaacb74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casa Nova 9.6 km from Santa Cruz 9.2/10 Wonderful (51) "Atendimento excelente. Todos os funcionários muito prestativos. Amei a estadia " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) emerson CA $98 CA $103 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Cuiaba-Hotels-Hotel-Casa-Nova.h34178870.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1590000/1584100/1584029/b3453ec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1590000/1584100/1584029/1aa0a604.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1590000/1584100/1584029/d6f07a47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1590000/1584100/1584029/b8b9e2bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Deville Prime Cuiabá Da Goiabeira, 6.3 km from Santa Cruz 9.2/10 Wonderful (637) "Room very clean, shower works perfectly, ac is great and very nice breakfasr" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dan CA $141 CA $160 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Cuiaba-Hotels-Hotel-Deville-Prime-Cuiaba.h1584029.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-02&endDate=2025-12-03®ionId=553248635318496020&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Cruz Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. - UFMT - Central North - Centro Político Administrativo - Coxipó - Centro Sul [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318295256) ![UFMT map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:bnh%7EAfaguIEsFy%40kB%7DQcWeCaBsAO%7DVy%5DhSka%40vLfL%7C%40q%40hBpBbC%60a%40pEnJvQbVaP%7CR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5kbtcFGXsAXrP3NKuUHZt8hjlpw=) ### UFMT Travelers like the museums in UFMT, and UFMT Zoo is a top attraction you might want to visit. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318295256) ![San Pedro de Atacama featuring landscape views, tranquil scenes and a lake or waterhole](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/121000/121578-Piedras-Rojas--Red-Rocks-.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Rio de Janeiro showing modern architecture, a church or cathedral and religious elements](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/64000/64762-Rio-De-Janeiro-Cathedral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/7be9ba5a8bbab10852cdc96aef595cf6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6208201) ![Central North map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:t%7Ed%7EAxqluIoq%40m%5EfN%7DHdRgVnCh%40tMQjGlBpUvUq%5BzVlFxK%7DK%5E&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ITq0GdXIW95kzEU2G2Y0VSv7Ni0=) ### Central North You'll enjoy the waterfalls and riverfront in Central North. You might want to make time for a stop at Cine Teatro Cuiaba or Historical Museum of Mato Grosso. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6208201) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318478172) ![Centro Político Administrativo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%60l%7D%7DAb_iuIoDsDe%40yBuD_AkJkEicAai%40aHeGdBqDxBcCt%40%40dCuBvDuA%7C%40gArA%3F%60CyDlDsAZcBnA%5Dr%40kDnAOZwBwBsFtAkJs%40wAlBoFGmDrB%7BDd%40uCi%40%7BCqIoIrHcFhM_Olj%40%60b%40hCuErF_EnBIvEaBpA%60%40lBKnHyBbAXpCI%60CjRCzK%7C%40fCArBbCC%3Fn%40fKENbElBbE%7CE%7CCrGnBQ%60%40%7C%40%60%40Yn%40rIfErIuRqLaGtAmAl%40mB%7COZA%7CAvUS%3FXjBf%40UtC%7CCfEoc%40vo%40pGjEmAfBgNvQuCbBcHbAyBfA%7BVj%5EcHuLs%40sEiAgCaKIkEc%40iLhCcBrHsAlAsA%5C_BhBAvCcB%7EB%40%7E%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hTcF-nxiJfzKt0x00SgywaTtzKA=) ### Centro Político Administrativo Visitors to Centro Político Administrativo like its parks and riverfront, and Massairo Okamura Park is a sight worth a stop. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318478172) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318328553) ![Coxipó map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:lzl%7EAzcfuImAQmAaACcI_G_KyE%7DAgEwFaSmLuOwKm%40IcHnKiTjXqHcIpE%7BFaB_B%7BFeLUwOj%40gBc%40_BfFwDpAmDnEcF%60SrBnTyQ%7CCsMzSbJwCbFzLzHuDtBvA%7CA%60AnDhClERjFxNfR_GxJpX%7EOmGfV_AUwC%7EB_ET&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=oyV1Bu8sLWLtIOVb2qVBx7BCaYo=) ### Coxipó Travelers like the parks in Coxipó, and Ze Bolo Flo Park is a top attraction you might want to visit. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318328553) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318338473) ![Centro Sul map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:lzf%7EAz%7CmuIih%40%7Dh%40oBpBeEqD_GL_DqA%7CBwDda%40y%5BdYbQvCClDmDdASv%60%40%7EPaEbIqK%7EIyZp%5C&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Z-pog48hm_NzOx7b-Dd9bgOxCzw=) ### Centro Sul Travelers like the museums in Centro Sul, and Centro Geodésico da America do Sul is a top attraction you might want to visit. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318338473) ## Top Santa Cruz Hotel Reviews ### Hotel Deville Prime Cuiabá 10/10 Excellent "Room very clean, shower works perfectly, ac is great and very nice breakfasr" [](https://expedia.ca/Cuiaba-Hotels-Hotel-Deville-Prime-Cuiaba.h1584029.Hotel-Information) ### HITS PANTANAL HOTEL AEROPORTO 10/10 Excellent "A nice hotel, friendly staff, adjacent to a shopping mall, close to the airport but very quiet, a very efficient transfer service to to pick me up from the airport. But what really stands out is the amazing swimming pool. One of the best pools I encountered at a hotel for swimming laps! I can definately recommend this hotel." [](https://expedia.ca/Cuiaba-Hotels-Hits-Pantanal-Hotel.h6603464.Hotel-Information) ### Amazon Aeroporto Hotel 10/10 Excellent "Very clean hotel with wondeful staff" [](https://expedia.ca/Varzea-Grande-Hotels-Amazon-Aeroporto-Hotel.h91023356.Hotel-Information) ### STARLIS HOME - Versátil 6/10 Okay "Room and property is nice enough. Only major complaint is that the master bed is tiny and very hard. Felt like a box spring, not a mattress. Otherwise, apartment is clean and AC was just enough no keep cool. " [](https://expedia.ca/Cuiaba-Hotels-Viva-Versatil.h37198826.Hotel-Information) ### Delmond Hotel 10/10 Excellent "My stay at the Delmond Hotel in Cuiabá was a very pleasant experience. The rooms are of great quality—spacious, clean, and comfortable. The staff were consistently professional and welcoming, making the stay even more enjoyable. Room service and the restaurant were both excellent, offering good variety and quality. Parking is also well managed, with hotel staff facilitating the process smoothly, which adds an extra layer of convenience. Overall, Delmond Hotel combines comfort, service, and practicality, making it an excellent choice in Cuiabá." [](https://expedia.ca/Cuiaba-Hotels-Delmond-Hotel.h8777102.Hotel-Information) ### Hotel 365 10/10 Excellent "Staff was very very friendly, Breakfast was good, would recommend and will stay here again when I travel to Cuiaba in the future." [](https://expedia.ca/Cuiaba-Hotels-Hotel-Presidencial.h6516031.Hotel-Information) ### Fly Hotel 2/10 Terrible "The check in took over 1 hour. The beds were dirty and so was the floor. " [](https://expedia.ca/Varzea-Grande-Hotels-Fly-Hotel.h95368274.Hotel-Information) ### Hotel Tainá - Aeroporto Cuiabá 4/10 Poor "You could hear cracking the entire night. Also, the blanked for the bed was very small. Bed was queen and blanket was a full size. They are super close to the airport and have no transportation (which I knew booking it). I just didn’t realize how hard it would be to cross the street with the bags and the baby in her stroller. " [](https://expedia.ca/Cuiaba-Hotels-Hotel-Taina-Aeroporto-Cuiaba.h11901351.Hotel-Information) ### Mato Grosso Palace Hotel 8/10 Good "Helpful stuff and good breakfast " [](https://expedia.ca/Cuiaba-Hotels-Mato-Grosso-Palace-Hotel.h26534.Hotel-Information) ## Frequently asked questions ### What is Santa Cruz like? > Travelers will be sure to find plenty to entertain them in Cuiabá's Santa Cruz neighborhood. ### Where is the best place to stay in Santa Cruz? > For your stay in Santa Cruz, [Alugo Apartamento no Centro de Cuiabá](https://www.expedia.ca/Cuiaba-Hotels-Alugo-Apartamento-No-Centro-De-Cuiaba.h103697354.Hotel-Information) is one of the top choices based on our traveler data. ### If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund? > Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the top deals on offer in Santa Cruz. ### What is there to do in this Cuiabá neighborhood? > UFMT Zoo, Museum of the Indigenous People, and Rondon Museum are just a few of the places to visit in and around Santa Cruz. While you're out sightseeing, Shopping 3 Americas and Ze Bolo Flo Park are a couple of additional sights to visit in Cuiabá. ## Explore a world of travel with Expedia - More ways to book - [Book Hotels in Santa Cruz on Expedia.com.br](https://www.expedia.com.br/Santa-Cruz-Cuiaba-Hoteis.0-n553248635318496020-0.Guia-de-Viagem-Filtrar-Hoteis)