Title: Visit Eastern Panama: Best of Eastern Panama Tourism | Expedia Travel Guide - Expedia.ca [Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.ca/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides) # Eastern Panama ## Travel Guide ![Eastern Panama](https://mediaim.expedia.com/destination/1/5d18772a3c60968c8280d6082bb3d1e6.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/482903472e1439a493a2dee83b010272.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/3d9eeb9430a538d415835dae66f32e6b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/e91e7dd2d90ea5b24911aac1bf6211b5.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/af03951a059f7966fe092201856ba764.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Eastern Panama Things to do - Eastern Panama Hotel Deals - Vacation Rentals in Eastern Panama ![Ciel y Miel ](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/7979d8c3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ciel y Miel Caillle Principale, Cacique, Provincia de Colón CA $650 CA $715 total Oct 6 - Oct 7 includes taxes & fees Stay at this 3-star beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ... 10/10 Exceptional! (9 reviews) "All was good" Reviewed on Jul 14, 2025 [](https://expedia.ca/Hotel-Search?startDate=06%2F10%2F2025&endDate=07%2F10%2F2025&selected=96734959&PinnedHotelID=96734959&HadPinnedHotel=true®ionId=6246114) ![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/ede84b95_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Ocean-Front Cabin with private bathroom on San Blas Island Diablo Island, Narganá, Guna Yala CA $262 CA $289 total Oct 7 - Oct 8 includes taxes & fees Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ... [](https://expedia.ca/Hotel-Search?startDate=07%2F10%2F2025&endDate=08%2F10%2F2025&selected=37766985&PinnedHotelID=37766985&HadPinnedHotel=true®ionId=6246114) ![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/a3494600_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cocotal La Guaira, Isla Grande, Provincia de Colón CA $58 CA $126 total Oct 8 - Oct 9 includes taxes & fees Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ... 10/10 Exceptional! (2 reviews) "It was old, quaint interesting, would recommend" Reviewed on Sep 5, 2025 [](https://expedia.ca/Hotel-Search?startDate=08%2F10%2F2025&endDate=09%2F10%2F2025&selected=116789972&PinnedHotelID=116789972&HadPinnedHotel=true®ionId=6246114) [See all 176 properties in Eastern Panama](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=06%2F10%2F2025&endDate=07%2F10%2F2025®ionId=6246114) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Over the Water Cabin on San Blas Island 9.542876, -78.899058, Narganá, San Blas Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime ... 7/10 Good! (6 reviews) "Very nice. And I liked the food" Reviewed on Aug 14, 2025 [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ![BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES](https://images.trvl-media.com/lodging/31000000/30800000/30792300/30792236/afc188ba_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES Santa Isabel Book a stay at this beach villa in Palenque. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Beautiful property "The property was stunning and the staff was amazing. Every meal prepared by the staff was better than the next." Reviewed on Jan 31, 2025 [](https://expedia.ca/Palenque-Hotels-Palenque-Spectacular-Caribbean-Ocean-Front-Property-In-Panama.h30792236.Hotel-Information) ![ Paradise Over the Water Cabins in San Blas](https://images.trvl-media.com/lodging/47000000/46950000/46948400/46948372/fe0394dd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Paradise Over the Water Cabins in San Blas G4V2 48, Narganá, Guna Yala Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Porvenir Museum ... "29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the ..." Reviewed on Sep 4, 2022 [](https://expedia.ca/El-Porvenir-Hotels-Newly-Built-Paradise-Cabins-In-San-Blas.h46948372.Hotel-Information) [See all properties in Eastern Panama](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6246114&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Eastern Panama hotel availability [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-05&endDate=2025-10-06) [Tonight](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-05&endDate=2025-10-06) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-05&endDate=2025-10-06) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-05&endDate=2025-10-06)[Oct 5 - Oct 6](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-05&endDate=2025-10-06) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-06&endDate=2025-10-07) [Tomorrow night](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-06&endDate=2025-10-07) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-06&endDate=2025-10-07) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-06&endDate=2025-10-07)[Oct 6 - Oct 7](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-06&endDate=2025-10-07) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [Next weekend](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025)[Oct 10 - Oct 12](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) ### Popular places to visit ![Isla Diablo](https://mediaim.expedia.com/destination/2/a97b784f0974336e0e332fb195502e82.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Isla Diablo Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.ca/Isla-Diablo-Nargana.d951034527519002624.Vacation-Attraction) #### Museum of the Kuna Nation You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Masargantupo. Stroll along the seaside or experience the area's festivals. [](https://expedia.ca/Museum-Of-The-Kuna-Nation-San-Blas-Islands.d553248621579133546.Vacation-Attraction) #### Isla Chichime Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.ca/Isla-Chichime-Nargana.d951034147716386816.Vacation-Attraction) ## Cities near Eastern Panama ![San Blas Islands](https://mediaim.expedia.com/destination/1/5d18772a3c60968c8280d6082bb3d1e6.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### San Blas Islands [](https://expedia.ca/San-Blas-Islands.dx6024116) ![Photo by Off The Beaten Track](https://mediaim.expedia.com/destination/2/3888985b47716adc7e8af07c1e2744d0.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Caimitillo [](https://expedia.ca/Caimitillo.dx829297769735790592) ![Narganá](https://mediaim.expedia.com/destination/1/5d18772a3c60968c8280d6082bb3d1e6.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Narganá [](https://expedia.ca/Nargana.dx829297845969362944) - Cities near Eastern Panama - Places of interest [San Blas Islands](https://expedia.ca/San-Blas-Islands.dx6024116)[Tupile](https://expedia.ca/Tupile.dx553248635963618492)[Carti](https://expedia.ca/Carti.dx553248635974498100)[Mandinga](https://expedia.ca/Mandinga.dx553248635975856894)[Camogantí](https://expedia.ca/Camoganti.dx829297382853201920)[Paya](https://expedia.ca/Paya.dx829297452726095872)[Púcuro](https://expedia.ca/Pucuro.dx829297458059177984)[Boca de Cupe](https://expedia.ca/Boca-De-Cupe.dx829297466781212672)[Yape](https://expedia.ca/Yape.dx829297475935293440)[El Real de Santa María](https://expedia.ca/El-Real-De-Santa-Maria.dx829297481505312768)[Pinogana](https://expedia.ca/Pinogana.dx829297485225668608)[Yaviza](https://expedia.ca/Yaviza.dx829297489688424448)[Metetí](https://expedia.ca/Meteti.dx829297497563209728)[Manuel Ortega](https://expedia.ca/Manuel-Ortega.dx829297506843123712)[Cirilo Guainora](https://expedia.ca/Cirilo-Guainora.dx829297515193970688)[Lajas Blancas](https://expedia.ca/Lajas-Blancas.dx829297526369701888)[Río Iglesias](https://expedia.ca/Rio-Iglesias.dx829297548421255168)[Agua Fría](https://expedia.ca/Agua-Fria.dx829297553955622912)[Cañita](https://expedia.ca/Canita.dx829297618541613056)[Las Margaritas](https://expedia.ca/Las-Margaritas.dx829297622907908096)[Tortí](https://expedia.ca/Torti.dx829297631527182336)[Caimitillo](https://expedia.ca/Caimitillo.dx829297769735790592)[Puerto Obaldía](https://expedia.ca/Puerto-Obaldia.dx829297796248002560)[Tubualá](https://expedia.ca/Tubuala.dx829297812280709120)[Ailigandí](https://expedia.ca/Ailigandi.dx829297826484744192) - [Isla Mamey](https://expedia.ca/Isla-Mamey-Colon.d553248623454093160.Vacation-Attraction) - [Cayos Holandeses](https://expedia.ca/Cayos-Holandeses-Guna-Yala.d553248621579133545.Vacation-Attraction) - [Colon Free Zone](https://expedia.ca/Colon-Free-Zone-Barrio-Sur.d6078503.Vacation-Attraction) - [Chagres National Park](https://expedia.ca/Chagres-National-Park-Panama.d6252818.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)