Otay Mesa Vacation Packages
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Top Holiday Package Deals in Otay Mesa
Price found within the past 48 hours. Click for updated prices.
Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
CA $999
per person
Nov 25 - Nov 30
found 5 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to San Diego (SAN)
8.6/10 Excellent! (2,060 reviews)
Very nice place we enjoyed it , would definitely recommend for a total relaxing visit .
Reviewed on Sep 22, 2026
The Beau Hotel Gaslamp Quarter San Diego
Downtown San Diego
CA $1,710
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to San Diego (SAN)
8.8/10 Excellent! (940 reviews)
Issue #1:
When I showed up at 3:30 (for a 3PM check-in), I was given a key to a room. When I went to the room, there was a maintenance person saying that the room would be ready in 30 minutes. I had to go down to the lobby and get moved to the room next door.
Issue #2:
The hotel was incredibly loud due to a wedding reception in the restaurant below. In fact, it was so loud I had to leave the hotel and go for a walk due to the sound and vibration in my room.
Issue #3:
I also got charged $12 for a damaged towel which they said was due to discoloration. The only way that towel could have been discolored was from something on the floor of the hotel room or their cleaning process.
Needless to say, I will never stay there again. And I recommend to anyone else to avoid this hotel.
Reviewed on Sep 21, 2026
Paradise Point Resort & Spa
Mission Bay
CA $1,423
per person
Oct 29 - Nov 1
found 11 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to San Diego (SAN)
8.8/10 Excellent! (2,852 reviews)
Our family had a great time! We enjoyed the different pools, miniature golf & treasure hunt. Our room and lobby were clean & the staff was attentive and helpful
Reviewed on Sep 21, 2026
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Downtown San Diego
3 out of top 10 points of interest in this area
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Pacific Beach
Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.
Mission Beach
Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Mission Bay
1 out of top 10 points of interest in this area
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
Otay Mesa Hotel Deals
Handlery Hotel
950 Hotel Cir N San Diego CA
CA $145
CA $166 total
Sep 28 - Sep 29
includes taxes & fees
8.4/10 Very good! (2,935 reviews)
"I had a really great stay at this hotel! The room was clean, comfortable, and well maintained, and the overall atmosphere was very welcoming. The staff were friendly and helpful, which made the experience even better. The location was also convenient and made it easy to get around. Everything about ..."
Reviewed on Sep 22, 2026
Best Western Seven Seas
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
CA $118
CA $136 total
Sep 29 - Sep 30
includes taxes & fees
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
CA $270
CA $384 total
Oct 18 - Oct 19
includes taxes & fees
8.8/10 Excellent! (2,886 reviews)
"Our family had a great time! We enjoyed the different pools, miniature golf & treasure hunt. Our room and lobby were clean & the staff was attentive and helpful"
Reviewed on Sep 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does an Otay Mesa vacation package cost?
Starting from as low as CA $999, a vacation package is your ticket to cheaper travel. Create your own Otay Mesa escape by choosing from our wide range of hotels, airfares and rental cars.
How do I get a cheap travel package to Otay Mesa?
Our Otay Mesa vacation packages mean plenty of savings for the savvy wanderer. For the best deal, simply bundle your hotel, flights and extras (such as activities) into a neat and tidy package. But impressive bargains are only the start of your next amazing adventure. When you book with Expedia, you'll have more than 550 air carriers and 1,000,000 hotel options all over the world to pick from. No matter your budget or style, there's a package that's perfect for you.
Where should I stay in Otay Mesa?
A getaway to Otay Mesa wouldn't be complete without paying a visit to North Island Credit Union Amphitheatre, Aquatica and White Water Canyon. Spend your evenings close to these tourist attractions and make sightseeing simple.
What are the top hotels in Otay Mesa?
Book a stay at Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel. It's one of this neighborhood's most sought-after hotels. Another reputable option in Otay Mesa is Quality Suites San Diego Otay Mesa.
How far in advance should I book my Otay Mesa vacation?
Your best bet is to book early. Air carriers typically release flights around a year prior to departure, and this is an ideal opportunity to score some rock-bottom prices. Boss just told you to take your vacation time next month? That's alright! Expedia are never short on fantastic deals to send you on the getaway of your dreams, at a price you can afford.
What does an Expedia Otay Mesa travel package include?
It comes down to what you want. If you're traveling alone, you might decide to bundle flights and hotels. Bringing the entire family to Otay Mesa? A travel package that includes rental cars, flights and hotels might be a better fit. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking an Otay Mesa travel package?
When you book your flights, hotels and car rentals together, you'll land terrific discounts. Whether you're organizing an island getaway in a villa or prefer to stay in a cozy apartment in the city, Expedia can help make it happen.
Can I choose my airline with an Otay Mesa Expedia vacation package?
You can, and with over 550 airlines to select from worldwide, you have loads of choice. Look through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Otay Mesa vacation package?
Don't worry if you're rethinking your Otay Mesa vacation package — it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We get that life can sometimes throw a spanner in the works, so make your way to our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.
Things to do
Crossing Borders: Tijuana Day Trip from San Diego
CA $129
per adult
94% of travellers recommend
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
CA $55
per adult
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.