Book The Best Hotels in Mayo River, VA for 2026 from CA $80 - Fully Refundable Options

A brick building with a large tree in front.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Mayo River

Pet friendly

Apartment

Condo

Pool

Cottage

Family friendly

Cabin

Waterpark

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Mayo River hotels

A room with a wooden floor, a sofa, a TV mounted on the wall, a coffee machine, and a small cabinet.

1. Tuggle's Gap Roadside Inn - Blue Ridge Parkway

Floyd

Travis

CA $139

CA $153 total

includes taxes & fees

Sep 25 - Sep 26

A modern dining area with a long counter, multiple chairs, a television, and a coffee station.

A gym with various exercise machines, a mirrored wall, and a window providing natural light.

A spacious lobby with a herringbone-patterned floor, a reception desk, and two green armchairs.

A hotel room with a glass-enclosed shower, a double bed with white bedding, a bedside table with a lamp, and a view of the outdoors through a window.

2. Comfort Inn Martinsville

Martinsville

Robert

CA $142

CA $159 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a bed, a chair, a desk, a lamp, and a window with curtains.

A cozy living room with two sofas, a coffee table, and a TV on a wooden stand. There are framed pictures on the wall and a window with curtains.

A spacious lobby with a high ceiling, wooden beams, and a chandelier. There are two wicker chairs and a small table.

A multi-story building with a prominent wooden structure, a stone base, and a flat roof.

3. Hotel Floyd

Floyd

Emily

CA $182

CA $201 total

includes taxes & fees

Sep 9 - Sep 10

A covered outdoor area with a stone facade, a central entrance, and potted plants.

A hotel lobby with a reception desk, chairs, and a patterned carpet.

A hotel room with a sofa, armchair, desk, television, and a large window with curtains.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and greenery.

4. Hampton Inn Martinsville

Martinsville

Carolyn

CA $233

CA $260 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with two beds, a desk, a mirror, and a red accent wall.

A room with a blue wall, a wooden dresser, a lamp, a chair, a rug, and a window with a view of a house.

A hotel room with a large bed, a desk with a computer, a chair, and a sofa.

A motel with a covered parking area and a sign indicating a vacancy.

5. Virginian Motel

Stuart

Troy

CA $113

CA $127 total

includes taxes & fees

Sep 10 - Sep 11

A large white house with a porch, surrounded by a grassy field and hills in the background.

A cozy dining area with wooden tables and white chairs, a brick wall, and a chalkboard menu.

A living room with two armchairs, a coffee table, and a rug. There are windows with yellow curtains and a view of the outdoors.

A fireplace with a decorative metal grate, a small figurine, and a vase of flowers.

6. Moonlight Manor Bed and Breakfast

Floyd

susan

CA $228

CA $252 total

includes taxes & fees

Sep 17 - Sep 18

A building with a large tree in front, a parking lot, and a clear sky.

A motel sign, a building with a stone facade, and a mailbox.

A road under a stone bridge with a speed limit sign of 25 mph.

A road sign with 'BLUE RIDGE PARKWAY' and 'NATIONAL PARK SERVICE' text, surrounded by trees and a clear sky.

7. Blue Ridge Mountain Inn

Meadows Of Dan

Phyllis

CA $120

CA $135 total

includes taxes & fees

Sep 20 - Sep 21

A hotel breakfast area with a counter, seating, and a refrigerator.

A reception area with a wooden counter, a desk with a computer, a potted plant, and a view of the outside.

A hotel room with a bed, desk, chair, TV, and a small kitchenette.

A lobby with a brown patterned sofa, a glass coffee table with a vase of flowers, two side tables with lamps, a large ornate mirror, a flat-screen TV, and a welcome sign.

8. Econo Lodge Martinsville

Martinsville

Jared

CA $84

CA $93 total

includes taxes & fees

Sep 27 - Sep 28

A room with a grey armchair, a wooden cabinet, a small wooden table, and a refrigerator.

A hotel lobby with a reception desk, wooden cabinets, a coffee machine, and a view of the parking lot.

A reception area with a counter, a sofa, and a rug with 'Scottish Inn' text.

A bedroom with a bed, desk, chair, and a television.

9. Scottish Inns Collinsville-Martinville

Collinsville

Daniel

CA $77

CA $86 total

includes taxes & fees

Sep 13 - Sep 14

A rectangular swimming pool with a white fence surrounding it, a sign indicating 'Travelodge', and a clear sky with clouds.

Two white commercial dryers side by side in a laundry room with beige walls.

A Travelodge hotel with a covered parking area, a single-story structure, and a large window on the front.

A hotel room with a TV, wooden furniture, and a large window with blinds.

10. Travelodge by Wyndham Ridgeway Martinsville Area

Ridgeway

Christopher

CA $94

CA $104 total

includes taxes & fees

Sep 20 - Sep 21

A staircase with a chandelier, a wooden door with glass panels, and a wooden bookcase with framed pictures.

A kitchen with white cabinets, a stainless steel refrigerator, a microwave, a stove, and a dining table with chairs.

A dining room with a wooden table, chairs, a chandelier, a piano, and a window with curtains.

A two-story house with a porch, surrounded by a brick wall and various plants.

11. Hunter House Bed and Breakfast

Madison

Jerome

CA $214

CA $236 total

includes taxes & fees

Sep 15 - Sep 16

A living room with two brown leather sofas, a glass coffee table, a patterned rug, a wall clock, and a painting.

A room with a television on a marble counter, a green armchair, a striped armchair, and a small wooden table.

A room with two green upholstered chairs, a small round table, a tall floor lamp, a wooden cabinet with drawers, and a mounted flat-screen TV.

A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.

12. Travel Inn

Ridgeway

Tina

CA $86

CA $95 total

includes taxes & fees

Sep 8 - Sep 9

A neatly made bed with white linens, a wooden headboard, and a bedside table with a lamp.

A room with a wooden chair, a small table with a potted plant, and a red chair.

A building with a sign that reads "Relax Inn."

A living room with two patterned sofas, a coffee table, a rug, and a potted plant.

13. Relax Inn

Collinsville

Sherri

CA $71

CA $80 total

includes taxes & fees

Sep 15 - Sep 16

A large, two-story house with a central entrance, surrounded by a well-maintained garden and trees.

A hallway with a staircase, a lamp, and a sofa.

A covered porch with a view of trees and a river. There are outdoor seating areas with chairs and a table.

A living room with a fireplace, a sofa, a coffee table, and a kitchen area with wooden cabinets and a countertop.

14. The Oakdale Inn

Martinsville

"This was a fantastic property and much nicer than being at a hotel for a week. The grounds are really pretty and the neighborhood is nice for walks. Erin was amazing and it was nice to have coffee in the morning, breakfast provided if you wanted it and a really quiet experience. Note that this is a house from the 1950s and modern amenities are there, but it's definitely like traveling back in time a little bit"

Don

CA $279

CA $314 total

includes taxes & fees

Sep 13 - Sep 14

A modern hotel lobby with a seating area, tables, and chairs.

A swimming pool with lounge chairs and a fence, surrounded by trees and a clear sky.

A self-service snack and beverage area with refrigerated cases and shelves stocked with snacks and drinks.

A modern room with a sofa, two side tables, a decorative wall, and a patterned rug.

15. Hampton Inn Eden

Eden

Rickesha

CA $154

CA $172 total

includes taxes & fees

Sep 20 - Sep 21

A building with a 'Baymont' sign, a blue door, and a planter with flowers.

A living room with a sofa, two patterned armchairs, a coffee table, a desk with a computer, and a lamp.

A hotel room with a large bed, two bedside tables, a chair, a window with curtains, and a radiator.

A reception area with a Baymont Inn sign, a framed welcome message, a map of nearby locations, and a decorative painting.

16. Baymont by Wyndham Eden

Eden

Debbie

CA $138

CA $155 total

includes taxes & fees

Sep 20 - Sep 21

A wooden deck with outdoor seating, overlooking a forested valley.

A cozy lounge area with a fireplace, comfortable seating, and large windows offering a view of the outdoors.

A large, historic estate with a prominent tower and multiple buildings, surrounded by lush greenery and a golf course.

A spacious lobby with large windows offering a view of autumn foliage and hills. Furnishings include sofas, chairs, and a coffee table.

17. The Lodge at Primland, Auberge Collection

Meadows Of Dan

Brenda

CA $1,936

CA $2,244 total

includes taxes & fees

Sep 21 - Sep 22

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Mayo River attractions

Reynolds Homestead

You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.

See properties

Learn more about Mayo River

Head to sights like Reynolds Homestead as you discover the local area in Mayo River.

See all hotels in Mayo River

Top Mayo River Hotel Reviews

Travelodge by Wyndham Ridgeway Martinsville Area

10/10 Excellent

"Clean room"

Hotel Floyd

10/10 Excellent

"Great place to stay!"

Econo Lodge Martinsville

10/10 Excellent

"Very accommodating and respectful, my grandmother was able to get in my room on her first floor easily, which I was very grateful for!"

Get Cozy & take in the beauty of Groundhog Mountain @ the Cozy Doe!

10/10 Excellent

"The house was perfect! It was cute, cozy and had everything needed to make the stay comfortable."

The Lodge at Primland, Auberge Collection

8/10 Good

"Expedia y la propiedad no aclararon los cargos y tuve que esperar casi 1 hora a que acreditaron el total del dinero que ya había pagado por adelantado. Reserven directamente"

Travel Inn

10/10 Excellent

"Owner was very kind and accommodating!"

Comfort Inn Martinsville

8/10 Good

"The hotel is a great place to stay very clean the whole 6 days I was there the fitness room was out of order also the women that works for housekeeping always have a attitude."

Tuggle's Gap Roadside Inn - Blue Ridge Parkway

8/10 Good

"The check in process was different as in we had to call to check in. There is no front desk like most hotels. Now that I know that I would stay there again. Room was clean. A peaceful and friendly environment and very close access to the Blue Ridge Parkway."

Oasis Pool OPEN YEAR ROUND Private Fire Pit Modern Views

10/10 Excellent

"Incredible Experience all the way around. I enjoyed every moment of my journey and never wanted it to end. Breath takingly Beautiful. Everything you could imagine and more, right at your finger tips. Unforgettable. I am so glad that I came here! "

More cheap stays in Mayo River

Econo Lodge Martinsville

1755 Virginia Ave Martinsville VA

CA $84

CA $93 total

Sep 27 - Sep 28

includes taxes & fees

6.6/10 (545 reviews)

Tuggle's Gap Roadside Inn - Blue Ridge Parkway

3351 Parkway Ln S Floyd VA

CA $139

CA $153 total

Sep 25 - Sep 26

includes taxes & fees

9.2/10 Wonderful! (183 reviews)

Baymont by Wyndham Eden

716 Linden Dr Eden NC

CA $138

CA $155 total

Sep 20 - Sep 21

includes taxes & fees

Hampton Inn Eden

724 S Van Buren Rd Eden NC

CA $154

CA $172 total

Sep 20 - Sep 21

includes taxes & fees

Hotel Floyd

300 Rick Lewis Way Floyd VA

CA $182

CA $201 total

Sep 9 - Sep 10

includes taxes & fees

9.8/10 Exceptional! (537 reviews)

Hampton Inn Martinsville

50 Hampton Dr Martinsville VA

CA $233

CA $260 total

Sep 20 - Sep 21

includes taxes & fees

Hotels in Mayo River with star rating

Explore a world of travel with Expedia

Book Hotels in Mayo River on Expedia.com

Find hotels in Mayo River, VA from CA $80

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Mayo River

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mayo River hotels

1. Tuggle's Gap Roadside Inn - Blue Ridge Parkway

2. Comfort Inn Martinsville

3. Hotel Floyd

4. Hampton Inn Martinsville

5. Virginian Motel

6. Moonlight Manor Bed and Breakfast

7. Blue Ridge Mountain Inn

8. Econo Lodge Martinsville

9. Scottish Inns Collinsville-Martinville

10. Travelodge by Wyndham Ridgeway Martinsville Area

11. Hunter House Bed and Breakfast

12. Travel Inn

13. Relax Inn

14. The Oakdale Inn

15. Hampton Inn Eden

16. Baymont by Wyndham Eden

17. The Lodge at Primland, Auberge Collection

Stay near popular Mayo River attractions

Reynolds Homestead

Learn more about Mayo River

Top Mayo River Hotel Reviews

Travelodge by Wyndham Ridgeway Martinsville Area

Hotel Floyd

Econo Lodge Martinsville

Get Cozy & take in the beauty of Groundhog Mountain @ the Cozy Doe!

The Lodge at Primland, Auberge Collection

Travel Inn

Comfort Inn Martinsville

Tuggle's Gap Roadside Inn - Blue Ridge Parkway

Oasis Pool OPEN YEAR ROUND Private Fire Pit Modern Views

More cheap stays in Mayo River

Econo Lodge Martinsville

Tuggle's Gap Roadside Inn - Blue Ridge Parkway

Baymont by Wyndham Eden

Hampton Inn Eden

Hotel Floyd

Hampton Inn Martinsville

Hotels in Mayo River with star rating

Explore a world of travel with Expedia

Go further with the Expedia app