Book The Best Hotels in Mayo River, VA for 2026 from CA $76 - Fully Refundable Options

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Our top choices for Mayo River hotels

A modern dining area with a long counter, multiple chairs, a television, and a coffee station.

A hotel room with a glass-enclosed shower, a double bed with white bedding, a bedside table with a lamp, and a view of the outdoors through a window.

A spacious lobby with a herringbone-patterned floor, a reception desk, and two green armchairs.

A Comfort Inn hotel with a symmetrical facade, multiple windows, and a central entrance with a blue awning.

1. Comfort Inn Martinsville

Martinsville

Gustabo

CA $139

CA $156 total

includes taxes & fees

Nov 15 - Nov 16

A hotel breakfast area with a counter, seating, and a refrigerator.

A reception area with a wooden counter, a desk with a computer, a potted plant, and a view of the outside.

A gym with treadmills, elliptical machines, and weight equipment.

A hotel room with a bed, desk, chair, TV, and a small kitchenette.

2. Econo Lodge Martinsville

Martinsville

DARREL

CA $91

CA $101 total

includes taxes & fees

Oct 26 - Oct 27

A covered outdoor area with a stone facade, a central entrance, and potted plants.

A hotel room with a flat-screen TV, a desk with a chair, a sofa, and a window with curtains.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and greenery.

A hotel lobby with a reception desk, chairs, and a patterned carpet.

3. Hampton Inn Martinsville

Martinsville

LELAND

CA $254

CA $282 total

includes taxes & fees

Nov 8 - Nov 9

A building with a large tree in front, a parking lot, and a clear sky.

A motel sign, a building with a stone facade, and a mailbox.

A bedroom with a wooden floor, a bed with white bedding, a nightstand with a lamp, a dresser, and a red suitcase.

A compact kitchenette with a wooden desk, a stainless steel refrigerator, a microwave, a coffee maker, and a bedside table with a lamp.

4. Blue Ridge Mountain Inn

Meadows Of Dan

Todd

CA $137

CA $154 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with two beds, a desk, a mirror, and a red accent wall.

A brick building with a large window displaying an 'OPEN' sign, a small balcony, and a sign indicating an office.

A room with a blue wall, a wooden dresser, a lamp, a chair, a rug, and a window with a view of a house.

A motel with a covered parking area and a sign indicating a vacancy.

5. Virginian Motel

Stuart

Adriana

CA $95

CA $106 total

includes taxes & fees

Oct 20 - Oct 21

A room with a grey armchair, a wooden cabinet, a small wooden table, and a refrigerator.

A reception area with a counter, a sofa, and a rug with 'Scottish Inn' text.

A small, single-story building with a registration sign, a covered waiting area, and a parking lot.

A bedroom with a bed, desk, chair, and a television.

6. Scottish Inns Collinsville-Martinville

Collinsville

Daniel

CA $85

CA $94 total

includes taxes & fees

Nov 19 - Nov 20

A room with a wooden floor, a sofa, a TV mounted on the wall, a coffee machine, and a small cabinet.

7. Tuggle's Gap Roadside Inn - Blue Ridge Parkway

Floyd

Christina

CA $142

CA $156 total

includes taxes & fees

Nov 8 - Nov 9

A neatly made bed with white linens, a wooden headboard, and a bedside table with a lamp.

A living room with two patterned sofas, a coffee table, a rug, and a potted plant.

A building with a sign that reads "Relax Inn."

A hotel reception area with a counter, a coffee machine, and various amenities like napkins, tissues, and a plant.

8. Relax Inn

Collinsville

Sherri

CA $68

CA $76 total

includes taxes & fees

Oct 22 - Oct 23

A hotel room with a bed, a chair, a desk, a lamp, and a window with curtains.

A covered outdoor area with stone flooring, wooden pillars, and a hanging flower basket.

A spacious lobby with a high ceiling, wooden beams, and a chandelier. There are two wicker chairs and a small table.

A cozy living room with two sofas, a coffee table, and a TV on a wooden stand. There are framed pictures on the wall and a window with curtains.

9. Hotel Floyd

Floyd

John

CA $187

CA $206 total

includes taxes & fees

Nov 1 - Nov 2

A large white house with a porch, surrounded by a grassy field and hills in the background.

A cozy dining area with wooden tables and white chairs, a brick wall, and a chalkboard menu.

A bathroom with a shower curtain featuring a botanical design and the words "Relax. Soul. Unwind." and "Bath House."

A living room with two armchairs, a coffee table, and a rug. There are windows with yellow curtains and a view of the outdoors.

10. Moonlight Manor Bed and Breakfast

Floyd

susan

CA $238

CA $263 total

includes taxes & fees

Oct 24 - Oct 25

A rectangular swimming pool with a white fence surrounding it, a sign indicating 'Travelodge', and a clear sky with clouds.

Two white commercial dryers side by side in a laundry room with beige walls.

A Travelodge hotel with a covered parking area, a single-story structure, and a large window on the front.

A hotel room with a TV, wooden furniture, and a large window with blinds.

11. Travelodge by Wyndham Ridgeway Martinsville Area

Ridgeway

Cory

CA $102

CA $114 total

includes taxes & fees

Nov 8 - Nov 9

A living room with two brown leather sofas, a glass coffee table, a patterned rug, a wall clock, and a painting.

A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.

A reception area with a desk, computer, and a glass display case containing snacks.

A room with two green upholstered chairs, a small round table, a tall floor lamp, a wooden cabinet with drawers, and a mounted flat-screen TV.

12. Travel Inn

Ridgeway

Salomón

CA $71

CA $79 total

includes taxes & fees

Oct 28 - Oct 29

A building with a 'Baymont' sign, a blue door, and a planter with flowers.

A reception area with a Baymont Inn sign, a framed welcome message, a map of nearby locations, and a decorative painting.

A hotel room with a large bed, two bedside tables, a chair, a window with curtains, and a radiator.

A dining area with tables and chairs, a microwave, a coffee machine, and a television displaying a message.

13. Baymont by Wyndham Eden

Eden

Debbie

CA $126

CA $141 total

includes taxes & fees

Nov 15 - Nov 16

A staircase with a chandelier, a wooden door with glass panels, and a wooden bookcase with framed pictures.

A living room with a fireplace, two sofas, a coffee table, and a chandelier.

A kitchen with white cabinets, a stainless steel refrigerator, a microwave, a stove, and a dining table with chairs.

A two-story house with a porch, surrounded by a brick wall and various plants.

14. Hunter House Bed and Breakfast

Madison

Jerome

CA $220

CA $241 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with a bed, desk, TV, two chairs, a lamp, and artwork on the wall.

A hotel with a red roof, American flags, and a covered entrance.

A swimming pool with lounge chairs and a covered area, surrounded by trees and a clear sky.

A conference room with a round table, six chairs, a flat-screen TV on the wall, and a colorful carpet.

15. Hampton Inn Eden

Eden

Rickesha

CA $184

CA $207 total

includes taxes & fees

Nov 3 - Nov 4

A large, two-story house with a central entrance, surrounded by a well-maintained garden and trees.

A living room with a fireplace, a sofa, a coffee table, and a kitchen area with wooden cabinets and a countertop.

A spacious room with a grand piano, a marble-patterned sofa, and a large window with a view of greenery.

A covered porch with a view of trees and a river. There are outdoor seating areas with chairs and a table.

16. The Oakdale Inn

Martinsville

Oliver

CA $286

CA $322 total

includes taxes & fees

Oct 21 - Oct 22

A wooden deck with outdoor seating, overlooking a forested valley.

A spacious lobby with large windows offering a view of autumn foliage and hills. Furnishings include sofas, chairs, and a coffee table.

A large, historic estate with a prominent tower and multiple buildings, surrounded by lush greenery and a golf course.

A cozy lounge area with a fireplace, comfortable seating, and large windows offering a view of the outdoors.

17. The Lodge at Primland, Auberge Collection

Meadows Of Dan

Brenda

CA $3,180

CA $3,642 total

includes taxes & fees

Oct 28 - Oct 29

A bedroom with a bed, a TV mounted on the wall, a window, and a door leading outside.

A house with a gravel driveway and a grassy lawn.

A room with a wooden door, a small table with chairs, a ceiling fan, and a window with blinds.

A compact kitchen with a dining area, featuring a small refrigerator, a sink, and a stove. There are two chairs and a table with a yellow top.

18. 4 Mi to Blue Ridge Parkway: Floyd Studio w/ Yard

Floyd

CA $150

CA $242 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with two beds, a bedside table with lamps, a mirror, a window with yellow curtains, and a framed picture on the wall.

A bar area with a brick wall, wooden counter, and two blue chairs.

A brick building with green-framed windows and a door, a hose connected to a device on the ground, and a small planter with plants on the porch.

A corridor with green doors numbered 149 and 148, brick walls, and a concrete floor.

19. Eden Inn Motel

Eden

Linda

CA $88

CA $99 total

includes taxes & fees

Nov 3 - Nov 4

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Stay near popular Mayo River attractions

Reynolds Homestead

You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas.

See properties

Learn more about Mayo River

Head to sights like Reynolds Homestead as you discover the local area in Mayo River.

See all hotels in Mayo River

A brick building with a large tree in front.

Top Mayo River Hotel Reviews

Tuggle's Gap Roadside Inn - Blue Ridge Parkway

10/10 Excellent

"Easy to get to our room. Bed and pillows were amazing. Lovely location. Having a restaurant on stewas great. I would stay here again."

Blue Ridge Mountain Inn

10/10 Excellent

"Beautiful location, Clean & well heated room and friendly staff."

Econo Lodge Martinsville

10/10 Excellent

"Close to everything. Has everything."

Secluded Romantic Escape near Fairy Stone State Park, Virginia

10/10 Excellent

"This was perfect for a weekend getaway!"

Comfort Inn Martinsville

10/10 Excellent

"Great room and clean. The sliding front doors were out of commission and you had to open them manually. That was rough while moving luggage."

Hotel Floyd

10/10 Excellent

"Excellent large room where I could work and relax. Quality bed. Floyd is a gem of a city"

Creekside Cottage Near Floyd, VA, on 250 acres with deck and gas grill.

10/10 Excellent

"We enjoyed staying in the Garden House. It’s in a beautiful area with lots to explore in Floyd."

Spacious Chalet on the Blue Ridge Parkway - Early Check-in and Late Check-out!

10/10 Excellent

"This was the 2nd time I have stayed here and it was amazing as usual. The birds and view is amazing. As someone with anxiety, this was my happy place. Miriam is an amazing host, she lets you know everything that is needed. Wet sweet person. Beware of the steps lol (if you have bad knees) and poison ivy. It’s nature though I expect it. Best two days of my life."

Moonlight Manor Bed and Breakfast

10/10 Excellent

"Amazing place. Would highly recommend. Will be back 🙂"

More cheap stays in Mayo River

Econo Lodge Martinsville

1755 Virginia Ave Martinsville VA

CA $91

CA $101 total

Oct 26 - Oct 27

includes taxes & fees

6.6/10 (558 reviews)

Travelodge by Wyndham Ridgeway Martinsville Area

3841 Greensboro Rd Ridgeway VA

CA $102

CA $114 total

Nov 8 - Nov 9

includes taxes & fees

Baymont by Wyndham Eden

716 Linden Dr Eden NC

CA $126

CA $141 total

Nov 15 - Nov 16

includes taxes & fees

Hotel Floyd

300 Rick Lewis Way Floyd VA

CA $187

CA $206 total

Nov 1 - Nov 2

includes taxes & fees

9.6/10 Exceptional! (551 reviews)

Hampton Inn Eden

724 S Van Buren Rd Eden NC

CA $184

CA $207 total

Nov 3 - Nov 4

includes taxes & fees

Hampton Inn Martinsville

50 Hampton Dr Martinsville VA

CA $254

CA $282 total

Nov 8 - Nov 9

includes taxes & fees

Hotels in Mayo River with star rating

Explore a world of travel with Expedia

Book Hotels in Mayo River on Expedia.com

Find hotels in Mayo River, VA from CA $76

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Mayo River

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mayo River hotels

1. Comfort Inn Martinsville

2. Econo Lodge Martinsville

3. Hampton Inn Martinsville

4. Blue Ridge Mountain Inn

5. Virginian Motel

6. Scottish Inns Collinsville-Martinville

7. Tuggle's Gap Roadside Inn - Blue Ridge Parkway

8. Relax Inn

9. Hotel Floyd

10. Moonlight Manor Bed and Breakfast

11. Travelodge by Wyndham Ridgeway Martinsville Area

12. Travel Inn

13. Baymont by Wyndham Eden

14. Hunter House Bed and Breakfast

15. Hampton Inn Eden

16. The Oakdale Inn

17. The Lodge at Primland, Auberge Collection

18. 4 Mi to Blue Ridge Parkway: Floyd Studio w/ Yard

19. Eden Inn Motel

Stay near popular Mayo River attractions

Reynolds Homestead

Learn more about Mayo River

Top Mayo River Hotel Reviews

Tuggle's Gap Roadside Inn - Blue Ridge Parkway

Blue Ridge Mountain Inn

Econo Lodge Martinsville

Secluded Romantic Escape near Fairy Stone State Park, Virginia

Comfort Inn Martinsville

Hotel Floyd

Creekside Cottage Near Floyd, VA, on 250 acres with deck and gas grill.

Spacious Chalet on the Blue Ridge Parkway - Early Check-in and Late Check-out!

Moonlight Manor Bed and Breakfast

More cheap stays in Mayo River

Econo Lodge Martinsville

Travelodge by Wyndham Ridgeway Martinsville Area

Baymont by Wyndham Eden

Hotel Floyd

Hampton Inn Eden

Hampton Inn Martinsville

Hotels in Mayo River with star rating

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