Title: Book The Best Hotels in Mayo, SC for 2026 from CA $78 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Mayo](https://expedia.ca/Mayo-Vacation-Rentals.d553248634999378372.Travel-Guide-VacationRentals)[Mayo Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo.d553248634999378372.Car-Rental-Guide)[Mayo Vacation Packages](https://expedia.ca/Mayo.d553248634999378372.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Mayo, SC from CA $78 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mayo Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2025-12-16&d1=2025-12-16&endDate=2025-12-18&d2=2025-12-18&travelerType=family_friendly) Cabin [](https://www.expedia.ca/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2025-12-16&d1=2025-12-16&endDate=2025-12-18&d2=2025-12-18&lodging=CABIN) Pool [](https://www.expedia.ca/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2025-12-16&d1=2025-12-16&endDate=2025-12-18&d2=2025-12-18&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2025-12-16&d1=2025-12-16&endDate=2025-12-18&d2=2025-12-18&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2025-12-16&d1=2025-12-16&endDate=2025-12-18&d2=2025-12-18&lodging=APARTMENT) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2025-12-16&d1=2025-12-16&endDate=2025-12-18&d2=2025-12-18&amenities=PETS) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2025-12-16&d1=2025-12-16&endDate=2025-12-18&d2=2025-12-18&lodging=COTTAGE) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Mayo%2C+South+Carolina%2C+United+States+of+America®ionId=553248634999378372&latLong=35.084011%2C-81.859825&adults=2&startDate=2025-12-16&d1=2025-12-16&endDate=2025-12-18&d2=2025-12-18&amenities=WATER_PARK) ## Check prices for these dates Tonight [Dec 2 - Dec 3](https://www.expedia.ca/Hotel-Search?regionId=553248634999378372&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=553248634999378372&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248634999378372&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248634999378372&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 438 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Free daily full breakfast](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/bd03801f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/f5139881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/3ccb6df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Gaffney by IHG Gaffney 8.6/10 Excellent (412) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy CA $103 CA $112 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12020000/12018000/12017964/8df3c06c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### University Inn Shelby 8.6/10 Excellent (442) "Great place to stay in Boilings Springs! Go dawgs!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge CA $119 CA $134 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Shelby-Hotels-University-Inn.h12017964.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/c05bf676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/573947b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/1ebed4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Gaffney Gaffney 8.8/10 Excellent (664) "Clean room, great staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) gary CA $122 CA $133 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18800/18704/034bcb90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18800/18704/53dee440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18800/18704/e1ab73fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/18800/18704/73eada7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Gaffney I-85 Gaffney 7.6/10 Good (350) "My stay was pleasant and the breakfast was as expected. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $69 CA $78 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Gaffney-Hotels-Quality-Inn-Gaffney-I-85.h18704.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/43600/43561/f5ad33e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43600/43561/869747d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43600/43561/5edce749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/43600/43561/324586f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Gaffney Gaffney 7.4/10 Good (646) "Yes very friendly hostes" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $86 CA $96 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Gaffney-Hotels-Baymont-By-Wyndham-Gaffney.h43561.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/283600/283578/57c4ccac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/290000/283600/283578/83db464e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/290000/283600/283578/a8807d24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/290000/283600/283578/4d612a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Gaffney at I-85 Gaffney 7.6/10 Good (328) "Clean room nice staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward CA $94 CA $105 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Gaffney-Hotels-Sleep-Inn-Gaffney.h283578.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/1ac2fb4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/b3b1b4a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/e7b52d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/84ae320a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Spartanburg Spartanburg 9.2/10 Wonderful (806) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa CA $133 CA $148 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/13000000/12290000/12287900/12287884/b9d4da18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12290000/12287900/12287884/d39b4900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/13000000/12290000/12287900/12287884/d3731f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12290000/12287900/12287884/a233db65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Forest City 7.6/10 Good (292) "I didnt eat at the property. It is built like a motel but seemed clean. There is tons of parking. Lots of restaurants nearby." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kiecha CA $87 CA $98 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Forest-City-Hotels-Quality-Inn.h12287884.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/3a7e8dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/8449a857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/fd1d83c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites At WestGate Mall Spartanburg 8.2/10 Very good (1015) "Easy parking, parking lot had good lighting felt safe Breakfast had great choices always hot, I always like their waffles Rooms clean and spacious, bed was comfortable" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronald CA $130 CA $144 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/283200/283166/3e1dcc4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/290000/283200/283166/309c3b34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/290000/283200/283166/fbf5e6e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/290000/283200/283166/2609349d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Gaffney Gaffney 7.2/10 Good (435) "Breakfast rules un- real strict, room fine and reasonable price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe CA $89 CA $100 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Gaffney-Hotels-Red-Roof-Inn-Gaffney.h283166.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/182cbcd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/901c2d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/c45915aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427798/4a7d4697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Forest City by IHG Forest City 8.8/10 Excellent (501) "Fantastic place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olivia CA $150 CA $170 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Forest-City-Hotels-Holiday-Inn-Express-Forest-City.h1427798.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, desk, blackout drapes](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/e7d5d81c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/f343bb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, desk, blackout drapes](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/4c47e461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ECHO Suites Extended Stay by Wyndham Spartanburg Spartanburg 8.2/10 Very good (279) "Hotel is very nice and clean, was very pleased with the room. Rates are affordable. Checking in was great and front staff was very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Georganna CA $101 CA $114 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/eac10fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/8062e000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/6f095093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/bd6af703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Spartanburg-North I-85 Spartanburg 8.6/10 Excellent (1017) "Convenient location, nice coffee station in lobby, good breakfast, room was average, good enough for one night stopover as I needed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John M CA $110 CA $122 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Spartanburg-Hotels-Hampton-Inn-Spartanburg-North-I-85.h281618.Hotel-Information) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/a78c349a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/3180d623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/c9a89e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/d8583276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton Spartanburg Spartanburg 9.4/10 Exceptional (431) "The room was very nice and the staff was very professional " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John T CA $141 CA $157 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/b1fe8b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/6250116e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/6f365c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/90000/80200/80179/d0dba6c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Forest City Forest City 7.4/10 Good (703) "Good stay and nice location. Good staff friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $85 CA $95 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Forest-City-Hotels-Baymont-By-Wyndham-Forest-City.h80179.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/d5c39216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/52207431.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/60839f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/39000000/38440000/38436000/38435916/5cefdbcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan Duncan 9.4/10 Exceptional (232) "Very friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelli CA $165 CA $186 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-SpartanburgDuncan.h38435916.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26192/67411a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26192/90393b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10 AM to 10 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/26200/26192/5ad0f85c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/26200/26192/80b5443e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Spartanburg Waccamaw Spartanburg 7.2/10 Good (771) "Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jefferson CA $80 CA $88 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Spartanburg-Hotels-Days-Inn-By-Wyndham-Spartanburg-Waccamaw.h26192.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/ce555c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/b6aa0ccd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/f51046c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599844/52525d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Forest City Forest City 9.4/10 Exceptional (416) "Clean room; clean property; great staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda CA $182 CA $206 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Forest-City-Hotels-Hampton-Inn-Suites-Forest-City.h21599844.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/cc478588.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/39a31823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/0ee8358f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/42900/42864/01fd9505.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Spartanburg Northwest by IHG Spartanburg 7.6/10 Good (832) "Breakfast was not free but our stay was enjoyable overall. Clean and convenient location for my work trip and staff was really friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $122 CA $136 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Spartanburg-Hotels-Holiday-Inn-Spartanburg-Northwest.h42864.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116600/116563/6e11f252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/120000/116600/116563/668ebde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116563/22b029ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116600/116563/b82fdb2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn by Wyndham Duncan/Spartanburg Duncan 7.2/10 Good (518) "Staff was very accommodating. The whole place was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) RAYFIELD CA $100 CA $111 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/Duncan-Hotels-Microtel-Inn-By-Wyndham-DuncanSpartanburg.h116563.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=553248634999378372&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Hotels.d553248634999378372.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMayo-Hotels.d553248634999378372.Travel-Guide-Hotels) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=HTG_BF_PROMO_553248634999378372) ## More cheap stays in Mayo ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### ECHO Suites Extended Stay by Wyndham Spartanburg 490 W Blackstock Road Spartanburg SC CA $101 CA $114 total Dec 17 - Dec 18 includes taxes & fees 8/10 Very Good! (276 reviews) [](https://expedia.ca/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Comfort Suites At WestGate Mall](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites At WestGate Mall 458 West Blackstock Road Spartanburg SC CA $130 CA $144 total Jan 1 - Jan 2, 2026 includes taxes & fees 8.2/10 Very Good! (1,012 reviews) [](https://expedia.ca/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![Tru by Hilton Spartanburg](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/1ac2fb4d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru by Hilton Spartanburg 103 Franklin Avenue Spartanburg SC CA $133 CA $148 total Dec 28 - Dec 29 includes taxes & fees 9/10 Wonderful! (804 reviews) [](https://expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information) ![Holiday Inn Express Gaffney by IHG](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Gaffney by IHG 1031 HYATT STREET Gaffney SC CA $103 CA $112 total Dec 18 - Dec 19 includes taxes & fees 8.6/10 Excellent! (410 reviews) [](https://expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information) ![Days Inn by Wyndham Spartanburg Waccamaw](https://images.trvl-media.com/lodging/1000000/30000/26200/26192/67411a8e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Spartanburg Waccamaw 101 Outlet Rd Spartanburg SC CA $80 CA $88 total Dec 20 - Dec 21 includes taxes & fees 7.2/10 Good! (770 reviews) [](https://expedia.ca/Spartanburg-Hotels-Days-Inn-By-Wyndham-Spartanburg-Waccamaw.h26192.Hotel-Information) ![Hampton Inn Gaffney](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Gaffney 115 Nancy Creek Rd Gaffney SC CA $122 CA $133 total Dec 21 - Dec 22 includes taxes & fees 8.6/10 Excellent! (663 reviews) [](https://expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) ## Hotels in Mayo with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 28 properties [](https://expedia.ca/3Star-Mayo-Hotels.s30-0-d553248634999378372.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 87 properties [](https://expedia.ca/2Star-Mayo-Hotels.s20-0-d553248634999378372.Travel-Guide-Filter-Hotels) ## Recent reviews of Mayo hotels ![Four Points by Sheraton Spartanburg](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/a78c349a_y.jpg) ### Four Points by Sheraton Spartanburg 5/5 Excellent "I enjoyed my stay at the hotel " A verified traveller stayed at Four Points by Sheraton Spartanburg Posted 3 days ago [](https://expedia.ca/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) ![Extended Stay America Premier Suites - Greenville - Spartanburg - I-85](https://images.trvl-media.com/lodging/97000000/96870000/96862800/96862776/f0a08506_y.jpg) ### Extended Stay America Premier Suites - Greenville - Spartanburg - I-85 5/5 Excellent "Pet friendly " A verified traveller stayed at Extended Stay America Premier Suites - Greenville - Spartanburg - I-85 Posted 5 days ago [](https://expedia.ca/Duncan-Hotels-Extended-Stay-America-Premier-Suites-Greenville-Spartanburg-I-85.h96862776.Hotel-Information) ![Spartanburg Marriott](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/9ab88731_y.jpg) ### Spartanburg Marriott 5/5 Excellent "Beautiful hotel! Loved having a restaurant and bar onsite so I didn't have to venture out for food. The room was comfortable but our air didn't seem to cool as much as we would have liked. Overall very pleasant stay." A verified traveller stayed at Spartanburg Marriott Posted 7 days ago [](https://expedia.ca/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information) ![Hampton Inn Spartanburg-North I-85](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/eac10fcf_y.jpg) ### Hampton Inn Spartanburg-North I-85 5/5 Excellent "Friendly staff. Good comfortable bed. Clean. Great!" A verified traveller stayed at Hampton Inn Spartanburg-North I-85 Posted 7 days ago [](https://expedia.ca/Spartanburg-Hotels-Hampton-Inn-Spartanburg-North-I-85.h281618.Hotel-Information) ![Comfort Inn & Suites Spartanburg North](https://images.trvl-media.com/lodging/1000000/890000/888800/888726/1891ba77_y.jpg) ### Comfort Inn & Suites Spartanburg North 5/5 Excellent "Great staff, Great room, Hot breakfast, " A verified traveller stayed at Comfort Inn & Suites Spartanburg North Posted 7 days ago [](https://expedia.ca/Spartanburg-Hotels-Comfort-Inn-Suites-At-I-85.h888726.Hotel-Information) ![Best Western Spartanburg Northwest](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/d02ac737_y.jpg) ### Best Western Spartanburg Northwest 5/5 Excellent "Inviting Public Areas; Good Breakfast; Nice Room & Friendly Staff. " A verified traveller from Westminster stayed at Best Western Spartanburg Northwest Posted 8 days ago [](https://expedia.ca/Spartanburg-Hotels-Best-Western-Spartanburg-Northwest.h19764.Hotel-Information) ![Hilton Garden Inn Spartanburg](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/ff5159b8_y.jpg) ### Hilton Garden Inn Spartanburg 5/5 Excellent "Clean nicely appointed room and lobby/lounge area. Dinner at the restaurant is recommended. Breakfast buffet was nothing special. " A verified traveller stayed at Hilton Garden Inn Spartanburg Posted 10 days ago [](https://expedia.ca/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) ![Best Western Plus Spartanburg](https://images.trvl-media.com/lodging/1000000/300000/297100/297091/31143c0e_y.jpg) ### Best Western Plus Spartanburg 5/5 Excellent "Willy is awesome! Staff also great! Room spacious." A verified traveller stayed at Best Western Plus Spartanburg Posted 10 days ago [](https://expedia.ca/Spartanburg-Hotels-Best-Western-Plus-Spartanburg.h297091.Hotel-Information) ![Hampton Inn & Suites Spartanburg-I-26-Westgate Mall](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088159/2e33c020_y.jpg) ### Hampton Inn & Suites Spartanburg-I-26-Westgate Mall 5/5 Excellent "Yes" A verified traveller stayed at Hampton Inn & Suites Spartanburg-I-26-Westgate Mall Posted 10 days ago [](https://expedia.ca/Spartanburg-Hotels-Hampton-Inn-Suites-Spartanburg-I-26-Westgate-Mall.h1088159.Hotel-Information) ## Frequently asked questions ### Where is the best place to stay in Mayo? > [ECHO Suites Extended Stay by Wyndham Spartanburg](https://www.expedia.ca/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information), located 12.3 mi (19.8 km) from the heart of Mayo, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are [Comfort Suites At WestGate Mall](https://www.expedia.ca/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) and [Spartanburg Marriott](https://www.expedia.ca/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information). See all available [top hotels](https://www.expedia.ca/Hotel-Search?regionId=553248634999378372), or [vacation rentals in Mayo](https://www.expedia.ca/Mayo-Vacation-Rentals.d553248634999378372.Travel-Guide-VacationRentals). ### What are some of the best vacation home rentals in Mayo? > [Charming House near Gardner Webb](https://www.expedia.ca/Mooresboro-Hotels-Charming-House-Near-Gardner-Webb.h57522275.Hotel-Information): You might want to consider this vacation home rental near Mayo, which is located in a rural location and offers a garden, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all [vacation rentals in Mayo](https://www.expedia.ca/Mayo-Vacation-Rentals.d553248634999378372.Travel-Guide-VacationRentals). ### If I need to cancel my hotel reservation in Mayo, will I receive a refund? > Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by [fully refundable](https://www.expedia.ca/Hotel-Search?regionId=553248634999378372&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Mayo. ### How is it staying in Mayo? > Travelers to Mayo will find plenty to explore and enjoy. There are 439 hotels and other accommodations in the surrounding area. Find out more about [Mayo](https://www.expedia.ca/Mayo.dx553248634999378372). ### What are the top places to visit in Mayo? > Places to visit in the wider area include [Lake Blalock Park](https://www.expedia.ca/Lake-Blalock-Park-Chesnee.d911211331513061376.Vacation-Attraction), [Cowpens National Battlefield](https://www.expedia.ca/Cowpens-National-Battlefield-South-Carolina.d6232435.Vacation-Attraction), and [Boiling Springs Centre](https://www.expedia.ca/Boiling-Springs-Centre-Boiling-Springs.d911210635386511360.Vacation-Attraction). You'll also find [Gaffney Outlet Marketplace](https://www.expedia.ca/Gaffney-Premium-Outlets-Gaffney.d6232433.Vacation-Attraction) and [Milliken Arboretum](https://www.expedia.ca/Milliken-Arboretum-Spartanburg.d911210924455854080.Vacation-Attraction) in the area. Check out what more to see and do in Expedia's [Mayo guide](https://www.expedia.ca/Mayo.dx553248634999378372). ### What's the weather like in Mayo? > The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Mayo is 52 inches. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [Anglewood Hotels](https://www.expedia.ca/Anglewood-Hotels.d553248635975857985.Travel-Guide-Hotels) - [Blacksburg Hotels](https://www.expedia.ca/Blacksburg-Hotels.d183936.Travel-Guide-Hotels) - [Cheap Hotels in Boiling Springs](https://www.expedia.ca/Boiling-Springs-Hotels-Cheap-Hotels.0-0-d6278956-tCheapHotels.Travel-Guide-Filter-Hotels) - [Boiling Springs Hotels](https://www.expedia.ca/Boiling-Springs-Hotels.d6278956.Travel-Guide-Hotels) - [Campobello Hotels](https://www.expedia.ca/Campobello-Hotels.d6336224.Travel-Guide-Hotels) - [B&B in Chesnee](https://www.expedia.ca/Chesnee-Bed-And-Breakfast.d3000353103-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Chesnee](https://www.expedia.ca/Chesnee-Hotels-Cheap-Hotels.0-0-d3000353103-tCheapHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Chesnee](https://www.expedia.ca/Chesnee-Hotels-Historic-Hotel.0-0-d3000353103-tHistoricHotel.Travel-Guide-Filter-Hotels) - 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