Title: Mayo Vacation Packages & Trips 2026 from CA $932 | Expedia.ca [Hotels in Mayo](https://expedia.ca/Mayo-Hotels.d553248634999378372.Travel-Guide-Hotels)[Vacation Rentals in Mayo](https://expedia.ca/Mayo-Vacation-Rentals.d553248634999378372.Travel-Guide-VacationRentals)[Mayo Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo.d553248634999378372.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Mayo Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Top Mayo Vacation Deals Price found within the past 48 hours. Click for updated prices. ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG CA $932 per person Apr 28 - May 5 found 6 hours ago Roundtrip non-stop flight included Edmonton (YEG) to Greenville (GSP) 8.6/10 Excellent! (1,005 reviews) Courteous staff, clean room Reviewed on Feb 8, 2026 ![Landing Apartments - Lyman](https://images.trvl-media.com/lodging/120000000/119750000/119742800/119742739/ea508898_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Landing Apartments - Lyman CA $1,189 per person Apr 28 - May 5 found 6 hours ago Roundtrip non-stop flight included Edmonton (YEG) to Greenville (GSP) No reviews ![Holiday Inn Greenville - Woodruff Road by IHG](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/00aa6485_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Holiday Inn Greenville - Woodruff Road by IHG CA $1,038 per person Apr 28 - May 5 found 6 hours ago Roundtrip non-stop flight included Edmonton (YEG) to Greenville (GSP) 8.6/10 Excellent! (661 reviews) A very nice experience! The only thing was the indoor pool. It was cold during the evening but considering its winter. Its expected. Other than that. One of the best hotels that I've ever stayed at!!! Reviewed on Jan 5, 2026 ![Hampton Inn Greenville I-385 - Woodruff Rd.](https://images.trvl-media.com/lodging/1000000/70000/67700/67687/d20ea353_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hampton Inn Greenville I-385 - Woodruff Rd. CA $1,245 per person Apr 28 - May 5 found 6 hours ago Roundtrip non-stop flight included Edmonton (YEG) to Greenville (GSP) 8.8/10 Excellent! (786 reviews) Clean bathroom, spacious room. Reviewed on Jan 29, 2026 ## Ready to book your vacation to Mayo? Choose your dates ## Mayo Hotel Deals ![Sleep Inn Spartanburg Southwest](https://images.trvl-media.com/lodging/1000000/50000/42900/42867/5eb71761_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sleep Inn Spartanburg Southwest 501 South Blackstock Rd Spartanburg SC Fully refundable CA $84 CA $93 total Feb 15 - Feb 16 includes taxes & fees 5.8/10 (541 reviews) Usually we stay at cheap hotels when we are on the road traveling. And this one definitely qualified as that. However, this room was nice and clean, while I was short on towels and blankets, the front desk staff responded quickly. Best cheap hotel breakfast I've had in quite a while. Not a place ... Reviewed on Feb 6, 2026 [](https://expedia.ca/Hotel-Search?startDate=15%2F02%2F2026&endDate=16%2F02%2F2026&selected=42867&PinnedHotelID=42867&HadPinnedHotel=true®ionId=553248634999378372) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### ECHO Suites Extended Stay by Wyndham Spartanburg 490 W Blackstock Road Spartanburg SC Fully refundableReserve now, pay when you stay CA $107 CA $123 total Feb 12 - Feb 13 includes taxes & fees 8/10 Very Good! (340 reviews) Clean, comfort room, liked the walk in shower and the price was very good Reviewed on Feb 3, 2026 [](https://expedia.ca/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=105488071&PinnedHotelID=105488071&HadPinnedHotel=true®ionId=553248634999378372) ![Comfort Suites At WestGate Mall](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Suites At WestGate Mall 458 West Blackstock Road Spartanburg SC Fully refundableReserve now, pay when you stay CA $127 CA $143 total Mar 8 - Mar 9 includes taxes & fees 8.2/10 Very Good! (1,005 reviews) Staff was wonderful Reviewed on Feb 10, 2026 [](https://expedia.ca/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=2654329&PinnedHotelID=2654329&HadPinnedHotel=true®ionId=553248634999378372) [See all 454 properties in Mayo](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=11%2F02%2F2026&endDate=12%2F02%2F2026®ionId=553248634999378372) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app