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Hotels in Mark Twain, St. Louis

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Our top choices for Mark Twain hotels

1. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 7.4 km from Mark Twain
9.4 out of 10, Exceptional, (1,010 reviews)
"The room was clean and the breakfast was great! We will definitely be staying here again the next time we visit St. Louis."
United States
rodnina
The price is CA $179
CA $212 total
includes taxes & fees
Sep 1 - Sep 2
Hampton Inn & Suites St. Louis at Forest Park

2. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
12.6 km from Mark Twain
9.2 out of 10, Wonderful, (3,195 reviews)
"Enjoyed our stay! Would stay here again!"
United States
Darren
The price is CA $124
CA $146 total
includes taxes & fees
Aug 30 - Aug 31
Pear Tree Inn St. Louis Airport

3. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
5.6 km from Mark Twain
8.8 out of 10, Excellent, (1,136 reviews)
"Great property in a great area!"
United States
Tony
The price is CA $126
CA $149 total
includes taxes & fees
Aug 31 - Sep 1
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 8.4 km from Mark Twain
8.6 out of 10, Excellent, (4,259 reviews)
"Great location!"
United States
Megan
The price is CA $185
CA $218 total
includes taxes & fees
Aug 28 - Aug 29
Hyatt Regency St. Louis at The Arch

5. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.4 km from Mark Twain
9.0 out of 10, Wonderful, (3,380 reviews)
"Very enjoyable stay"
United States
Edward Marion
The price is CA $128
CA $150 total
includes taxes & fees
Sep 6 - Sep 7
Clayton Plaza Hotel & Extended Stay

6. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 6 km from Mark Twain
8.6 out of 10, Excellent, (1,015 reviews)
"Very nice hotel staff were great water was hot the entire stay clean rooms"
United States
Khristina
The price is CA $157
CA $183 total
includes taxes & fees
Aug 30 - Aug 31
Aloft by Marriott St Louis Central West End

7. Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station
3.0 star property
Downtown West, 7.3 km from Mark Twain
9.4 out of 10, Exceptional, (1,523 reviews)
"The place was clean staff was really helpful. I would definitely stay here again !"
United States
Jose
The price is CA $186
CA $221 total
includes taxes & fees
Aug 30 - Aug 31
Drury Plaza Hotel St. Louis Union Station

8. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
11.2 km from Mark Twain
9.2 out of 10, Wonderful, (1,013 reviews)
"I highly recommend this hotel, will definitely use them in the future"
United States
Paige
The price is CA $151
CA $186 total
includes taxes & fees
Sep 20 - Sep 21
Hyatt Select St. Louis Airport

9. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
3.0 star property
12.6 km from Mark Twain
9.2 out of 10, Wonderful, (1,731 reviews)
"Clean property, friendly staff and a good breakfast. Overall a good stay!"
United States
Steven
The price is CA $152
CA $179 total
includes taxes & fees
Aug 26 - Aug 27
Wingate by Wyndham St. Louis Airport

10. AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 5.3 km from Mark Twain
9.0 out of 10, Wonderful, (829 reviews)
"I liked the hotel partly due to its excellent location. The staff was great, and the room extremely comfortable."
United States
chris
The price is CA $197
CA $232 total
includes taxes & fees
Sep 3 - Sep 4
AC Hotel St. Louis Central West End

11. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 7.1 km from Mark Twain
9.2 out of 10, Wonderful, (1,011 reviews)
"Everything was absolutely perfect!!!"
United States
Erik
The price is CA $172
CA $205 total
includes taxes & fees
Sep 1 - Sep 2
Fairfield Inn & Suites by Marriott St. Louis Downtown

12. Hilton Garden Inn St. Louis Airport

Hilton Garden Inn St. Louis Airport
3.0 star property
Berkeley, 7.8 km from Mark Twain
8.4 out of 10, Very good, (1,005 reviews)
"Great stay for being stranded to due weather conditions"
United States
Darryl
The price is CA $209
CA $244 total
includes taxes & fees
Aug 28 - Aug 29
Hilton Garden Inn St. Louis Airport

13. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 7.7 km from Mark Twain
9.0 out of 10, Wonderful, (1,050 reviews)
"It was great for a downtown hotel."
United States
Spencer David
The price is CA $145
CA $172 total
includes taxes & fees
Sep 3 - Sep 4
Courtyard by Marriott St. Louis Downtown/Convention Center

14. Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 7 km from Mark Twain
8.8 out of 10, Excellent, (2,170 reviews)
"Enjoyed my stay location was great Guest services Stephanie was excellent"
United States
SHARI
The price is CA $161
CA $188 total
includes taxes & fees
Aug 30 - Aug 31
Pear Tree Inn St. Louis Near Union Station

15. The West End

The West End
2.0 star property
Central West End, 5.4 km from Mark Twain
8.6 out of 10, Excellent, (619 reviews)
"Good and comfortable place to stay"
United States
Isabella
The price is CA $108
CA $154 total
includes taxes & fees
Sep 7 - Sep 8
The West End

16. Moonrise Hotel

Moonrise Hotel
4.0 star property
6.3 km from Mark Twain
9.0 out of 10, Wonderful, (2,030 reviews)
"Nice atmosphere, clean hotel."
United States
Vernon
The price is CA $200
CA $238 total
includes taxes & fees
Aug 30 - Aug 31
Moonrise Hotel

17. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
9 km from Mark Twain
9.4 out of 10, Exceptional, (1,019 reviews)
"It was nice places probably would stay there again."
United States
Chris
The price is CA $205
CA $240 total
includes taxes & fees
Aug 30 - Aug 31
Drury Inn & Suites St. Louis Forest Park

18. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 7.8 km from Mark Twain
9.0 out of 10, Wonderful, (1,349 reviews)
"Clean and very nice hotel."
United States
Matthew
The price is CA $168
CA $200 total
includes taxes & fees
Sep 9 - Sep 10
Embassy Suites by Hilton St. Louis Downtown

19. Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 5.4 km from Mark Twain
8.8 out of 10, Excellent, (1,013 reviews)
"Location is great"
United States
Simon
The price is CA $200
CA $250 total
includes taxes & fees
Aug 30 - Aug 31
Hotel Indigo St Louis - Central West End by IHG

20. DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 5.9 km from Mark Twain
8.4 out of 10, Very good, (1,002 reviews)
"Always a good place to stay when we have a trip to the doctor at Barnes Jewish or WashU"
United States
Kevin
The price is CA $197
CA $233 total
includes taxes & fees
Sep 3 - Sep 4
DoubleTree by Hilton St. Louis Forest Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mark Twain

Find the best Mark Twain areas and neighborhoods for the activities you enjoy most. Learn more about Mark Twain
Learn more about Mark Twain

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Mark Twain Hotel Reviews

Frequently asked questions

What's it like in Mark Twain?
Travelers will be sure to find plenty to entertain them in St. Louis's Mark Twain neighborhood.
If I need to cancel my hotel reservation in Mark Twain, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best deals available in Mark Twain.
What is there to do around this St. Louis neighborhood?
Bellefontaine Cemetery, Calvary Cemetery, and Julia Davis Branch Library are just a few of the places to visit in and around Mark Twain. Shelley House and The Ville Monument are also worth a visit when you're out sightseeing in St. Louis.