Title: Book the Best Key Largo SPA Resorts from CA $224 - Spa Hotels in Key Largo, FL | Expedia.ca [Key Largo Travel Guide](https://expedia.ca/Key-Largo.dx8369)[Hotels in Key Largo](https://expedia.ca/Key-Largo-Hotels.d8369.Travel-Guide-Hotels)[Vacation Rentals in Key Largo](https://expedia.ca/Key-Largo-Vacation-Rentals.d8369.Travel-Guide-VacationRentals)[Flights to Key Largo](https://expedia.ca/Cheap-Flights-To-Key-Largo.d8369.Travel-Guide-Flights)[Things to do in Key Largo](https://expedia.ca/Things-To-Do-In-Key-Largo.d8369.Travel-Guide-Activities)[Key Largo Car Rentals](https://expedia.ca/Car-Rentals-In-Key-Largo.d8369.Car-Rental-Guide)[Key Largo Vacation Packages](https://expedia.ca/Key-Largo.d8369.Destination-Travel-Guides) ![Key Largo featuring tropical scenes, a bay or harbour and general coastal views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63591-Key-Largo.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Key Largo, FL from CA $224 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Key Largo Spa Hotels Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=8369&startDate=2025-09-27&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=8369&startDate=2025-09-28&endDate=2025-09-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=8369&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=8369&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Key Largo Spa Hotels ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/e77d9aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/79d31a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/981feca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/e32d7e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa Matecumbe 9.2/10 Wonderful (1214) "Beautiful and relaxing hotel!!" CA $115 CA $224 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/fcd75612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/3c8fb00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/396da292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed | Terrace/patio](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/bf338fd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kona Kai Resort and Gallery - Adults Only Key Largo 9.8/10 Exceptional (259) "Had an amazing time everyone was very welcoming " CA $187 CA $249 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Key-Largo-Hotels-Kona-Kai-Resort-And-Gallery.h74501641.Hotel-Information) ![Body treatments, aromatherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/c2842ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/86c2e00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/f2f49899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/af093823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reefhouse Resort & Marina Key Largo 9.2/10 Wonderful (1308) "We had a great stay and will definitely stay here again and recommend to others. " CA $305 CA $399 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) ![Sauna, hot tub, steam room, body treatments, hot stone massages](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/0480bee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, beach cabanas, sun loungers, beach umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/d9cc2f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, beach cabanas, sun loungers, beach umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/8f8fe319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 3 Bedrooms, Pool Access, Bay View (Balcony/Patio, Private Pool) | Beach](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/10dd6c61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Playa Largo Resort & Spa, Autograph Collection Key Largo 9.0/10 Wonderful (1001) "By far one of the best hotels in the keys. " CA $333 CA $451 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) ![In-room dining](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/c244835e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/f15964b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/dc4f4949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, books](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/96d842c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Floating Bungalow by Stay Ombi Key Largo CA $1,114 CA $1,253 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Key-Largo-Hotels-Premium-Floating-Bungalow-By-Stay-Ombi.h108743380.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/3064d810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, open 8:00 AM to 6:00 PM, sun loungers](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/61575cce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/5be55ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Boating](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/a93dc7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Islands of Islamorada Matecumbe 9.8/10 Exceptional (66) "Absolutely outstanding resort. Legitimate 5 star property. " CA $602 CA $754 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Islamorada-Hotels-The-Islands-Of-Islamorada.h54774228.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12®ionId=8369&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Key Largo ### Top Key Largo attractions for a relaxing vacation Key Largo, Florida, is a haven for travellers seeking a blend of relaxation and adventure, making it a prime spot for those looking to indulge in spa hotels. Start your day with a serene sunrise at John Pennekamp Coral Reef State Park, where you can snorkel through vibrant coral reefs filled with marine life—an exhilarating way to connect with nature before unwinding at your hotel spa. For a unique experience, visit the African Queen Canal Cruise, where you can take a leisurely boat ride on the historic vessel while enjoying the beautiful tropical scenery. After a day of exploration, indulge in a soothing massage or facial treatment at one of the area's luxury spa hotels, such as the Playa Largo Resort & Spa, which boasts a tranquil setting and top services. A visit to the nearby Florida Keys Wild Bird Rehabilitation Center offers a chance to learn about local wildlife while enjoying the serene atmosphere—perfect for nature lovers. Finally, enjoy fresh seafood dining at local favourite, The Fish House, where you can savour the catch of the day while soaking in the relaxed coastal vibe. Staying in Key Largo not only provides easy access to these experiences but also allows you to rejuvenate in luxurious accommodations that prioritise your comfort and well-being. ### Find the best hotels & resorts with spas in Key Largo Key Largo offers a serene escape for travellers seeking rejuvenation and relaxation. Here are some top hotels that feature exceptional spa amenities to enhance your stay. [Reefhouse Resort & Marina](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) - **Why it's great for tailored spa getaway:** The Reefhouse Resort & Marina is an ideal choice for guests looking to indulge in a holistic spa experience, a remarkable review rating of 9.2. With a full-service spa on-site, guests can enjoy a variety of treatments, including deep tissue massages and detoxification wraps, ensuring a truly relaxing getaway. - **Other amenities:** In addition to its impressive spa offerings, the resort features a beautiful white sand beach and a heated outdoor pool perfect for unwinding. Guests can enjoy delicious meals at the beachfront restaurant or sip cocktails at the poolside bar. Additional facilities include complimentary kayaks for on-site exploration, hot tubs for a soothing soak, and a fitness centre for those who wish to stay active during their escape. - **Nearby attractions:** Caribbean Club Bar - 0.9 km, MarineLab Undersea Laboratory - 1.6 km, Rowell's Waterfront Park - 2 km [Playa Largo Resort & Spa, Autograph Collection](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) - **Why it's great for tailored spa getaway:** Playa Largo Resort & Spa is a luxurious retreat perfect for travellers focused on wellness, with a stellar review rating of 9.0. The full-service spa offers a range of treatments, from Swedish massages to Ayurvedic therapies, ensuring guests leave feeling refreshed and revitalised. - **Other amenities:** This upscale resort features a stunning beachfront location with private beach access and cabanas for ultimate relaxation. Guests can take advantage of the 24-hour outdoor pool, dine at the ocean-view restaurant, or unwind in the sauna and steam room. Additional offerings include kayaking, tennis courts, and a children’s club, making it a versatile choice for all guests. - **Nearby attractions:** Bluefin Rock Harbor Marina - 1 km, Baker's Cay Resort Beach - 1.4 km, North Nest Key - 3.8 km [Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://www.expedia.ca/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) - **Why it's great for tailored spa getaway:** With a review rating of 8.6, Baker's Cay Resort Key Largo is a charming destination for those looking to relax and rejuvenate. While the spa is accessible, guests can still enjoy a tranquil atmosphere and unwind in this beautiful setting. - **Other amenities:** Besides the spa, the resort provides a hot tub for relaxation, along with beachfront access and a variety of water sports including kayaking and scuba diving. Guests can enjoy casual dining at the beachfront restaurant or unwind with a drink at the poolside bar. Additional amenities include complimentary bicycles, yoga classes on-site, and a range of family-friendly activities. - **Nearby attractions:** Bluefin Rock Harbor Marina - 3.1 km, Baker's Cay Resort Beach - 0.1 km, Laura Quinn Wild Bird Sanctuary - 5.1 km ## Top Key Largo Hotel Reviews ![Reefhouse Resort & Marina](//images.trvl-media.com/lodging/1000000/10000/3500/3427/af093823_y.jpg) ### Reefhouse Resort & Marina 10/10 Excellent "We thoroughly enjoyed our stay at Reefhouse. Staff was friendly and helpful. Water and cookies at the front desk is a nice touch. Carlos, bartender at pool bar, went out of his way to make you feel welcome. When we saw him the following day he even remembered our drinks." [](https://expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) ![Amoray Dive Resort](//images.trvl-media.com/lodging/6000000/5320000/5311400/5311313/e12ff0a0_y.jpg) ### Amoray Dive Resort 10/10 Excellent "Absolutely loved it. Everyone was so nice, it was so pretty and clean. Definitely a Hidden gem " [](https://expedia.ca/Key-Largo-Hotels-Amoray-Resort.h5311313.Hotel-Information) ![Holiday Inn Key Largo by IHG](//images.trvl-media.com/lodging/1000000/10000/7300/7230/160ba216_y.jpg) ### Holiday Inn Key Largo by IHG 10/10 Excellent "Absolutely loved this property. Has everything you need for a relaxing stay" [](https://expedia.ca/Key-Largo-Hotels-Holiday-Inn-Key-Largo.h7230.Hotel-Information) ![Playa Largo Resort & Spa, Autograph Collection](//images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/489feb58_y.jpg) ### Playa Largo Resort & Spa, Autograph Collection 10/10 Excellent "By far one of the best hotels in the keys. " [](https://expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 10/10 Excellent "Bakers Cay was a wonderful place to stay and unwind. The service was outstanding and location perfect. Thank you" [](https://expedia.ca/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ![Marina Del Mar Resort and Marina](//images.trvl-media.com/lodging/1000000/10000/5200/5114/d42f8885_y.jpg) ### Marina Del Mar Resort and Marina 10/10 Excellent "Loved " [](https://expedia.ca/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information) ![Dove Creek Resort & Marina, Trademark Collection by Wyndham](//images.trvl-media.com/lodging/2000000/1190000/1186200/1186162/4ac8a422_y.jpg) ### Dove Creek Resort & Marina, Trademark Collection by Wyndham 10/10 Excellent "10/10" [](https://expedia.ca/Key-Largo-Hotels-Dove-Creek-Resort-Marina.h1186162.Hotel-Information) ![Courtyard by Marriott Key Largo](//images.trvl-media.com/lodging/1000000/50000/41600/41514/bc450ed1_y.jpg) ### Courtyard by Marriott Key Largo 10/10 Excellent "Very quiet, clean and excellent facilities. Ideal stop en route Key West." [](https://expedia.ca/Key-Largo-Hotels-Courtyard-By-Marriott-Key-Largo.h41514.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Key Largo? > Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday. ### What is the best spa hotel in Key Largo? > [Playa Largo Resort & Spa, Autograph Collection](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) is a top beach spa hotel featuring 3 restaurants, a 24-hour fitness center, a hair salon, and a bar. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Another popular spa hotel in Key Largo is [Reefhouse Resort & Marina](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information). ### How many spa hotels will I find in Key Largo? > Among Expedia's 1300 accommodation options in Key Largo, there are 2 spa hotels. ### What's there to see and do in Key Largo? > Enjoy Key Largo and visit Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina, and John Pennekamp Coral Reef State Park. If you have a bit of extra time while you're in the area, you might want to check out MarineLab Undersea Laboratory and Caribbean Club Bar. ### What is a Key Largo spa hotel? > Spa hotels in Key Largo provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. 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