Title: Book the Best Key Largo SPA Resorts from CA $408 - Spa Hotels in Key Largo, FL | Expedia.ca [Key Largo Travel Guide](https://expedia.ca/Key-Largo.dx8369)[Hotels in Key Largo](https://expedia.ca/Key-Largo-Hotels.d8369.Travel-Guide-Hotels)[Vacation Rentals in Key Largo](https://expedia.ca/Key-Largo-Vacation-Rentals.d8369.Travel-Guide-VacationRentals)[Flights to Key Largo](https://expedia.ca/Cheap-Flights-To-Key-Largo.d8369.Travel-Guide-Flights)[Things to do in Key Largo](https://expedia.ca/Things-To-Do-In-Key-Largo.d8369.Travel-Guide-Activities)[Key Largo Car Rentals](https://expedia.ca/Car-Rentals-In-Key-Largo.d8369.Car-Rental-Guide)[Key Largo Vacation Packages](https://expedia.ca/Key-Largo.d8369.Destination-Travel-Guides) ![Key Largo featuring tropical scenes, a bay or harbour and general coastal views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63591-Key-Largo.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Key Largo, FL from CA $408 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Key Largo Spa Hotels Tonight [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=8369&startDate=2025-11-01&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=8369&startDate=2025-11-02&endDate=2025-11-03&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=8369&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=8369&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Key Largo Spa Hotels ![Sauna, hot tub, steam room, body treatments, hot stone massages](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/0480bee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 3 Bedrooms, Pool Access, Bay View (Balcony/Patio, Private Pool) | Beach](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/10dd6c61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, beach cabanas, sun loungers, beach umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/d9cc2f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, beach cabanas, sun loungers, beach umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/8f8fe319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Playa Largo Resort & Spa, Autograph Collection Rock Harbor 9.0/10 Wonderful (1002) "By far one of the best hotels in the keys. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felipe CA $368 CA $491 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/fcd75612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Living area](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/4ae3e8fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/396da292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed | Terrace/patio](https://images.trvl-media.com/lodging/75000000/74510000/74501700/74501641/bf338fd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kona Kai Resort and Gallery - Adults Only Rock Harbor 9.8/10 Exceptional (274) "Property was very clean including beach, pool, and grounds." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Drew [](https://www.expedia.ca/Key-Largo-Hotels-Kona-Kai-Resort-And-Gallery.h74501641.Hotel-Information) ![Body treatments, aromatherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/c2842ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/86c2e00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/b2a768a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/f2f49899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reefhouse Resort & Marina Key Largo 9.2/10 Wonderful (1313) "Great resort and great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $320 CA $416 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) ![In-room dining](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/c244835e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/f15964b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/a7f8b8c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, books](https://images.trvl-media.com/lodging/109000000/108750000/108743400/108743380/96d842c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Floating Bungalow by Stay Ombi Key Largo CA $1,439 CA $1,619 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Key-Largo-Hotels-Premium-Floating-Bungalow-By-Stay-Ombi.h108743380.Hotel-Information) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/e77d9aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/981feca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/e32d7e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa Matecumbe 9.2/10 Wonderful (1266) "This resort was amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $279 CA $408 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/3064d810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Boating](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/a93dc7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/5be55ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/531fe0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Islands of Islamorada Matecumbe 9.8/10 Exceptional (68) "Beautiful property with great staff! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan CA $979 CA $1,178 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Islamorada-Hotels-The-Islands-Of-Islamorada.h54774228.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=8369&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Key Largo ### Top Key Largo attractions for a relaxing vacation Key Largo, Florida, is a haven for travellers seeking a blend of relaxation and adventure, making it a prime spot for those looking to indulge in spa hotels. Start your day with a serene sunrise at John Pennekamp Coral Reef State Park, where you can snorkel through vibrant coral reefs filled with marine life—an exhilarating way to connect with nature before unwinding at your hotel spa. For a unique experience, visit the African Queen Canal Cruise, where you can take a leisurely boat ride on the historic vessel while enjoying the beautiful tropical scenery. After a day of exploration, indulge in a soothing massage or facial treatment at one of the area's luxury spa hotels, such as the Playa Largo Resort & Spa, which boasts a tranquil setting and top services. A visit to the nearby Florida Keys Wild Bird Rehabilitation Center offers a chance to learn about local wildlife while enjoying the serene atmosphere—perfect for nature lovers. Finally, enjoy fresh seafood dining at local favourite, The Fish House, where you can savour the catch of the day while soaking in the relaxed coastal vibe. Staying in Key Largo not only provides easy access to these experiences but also allows you to rejuvenate in luxurious accommodations that prioritise your comfort and well-being. ### Find the best hotels & resorts with spas in Key Largo Key Largo offers a serene escape for travellers seeking rejuvenation and relaxation. Here are some top hotels that feature exceptional spa amenities to enhance your stay. [Reefhouse Resort & Marina](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) - **Why it's great for tailored spa getaway:** The Reefhouse Resort & Marina is an ideal choice for guests looking to indulge in a holistic spa experience, a remarkable review rating of 9.2. With a full-service spa on-site, guests can enjoy a variety of treatments, including deep tissue massages and detoxification wraps, ensuring a truly relaxing getaway. - **Other amenities:** In addition to its impressive spa offerings, the resort features a beautiful white sand beach and a heated outdoor pool perfect for unwinding. Guests can enjoy delicious meals at the beachfront restaurant or sip cocktails at the poolside bar. Additional facilities include complimentary kayaks for on-site exploration, hot tubs for a soothing soak, and a fitness centre for those who wish to stay active during their escape. - **Nearby attractions:** Caribbean Club Bar - 0.9 km, MarineLab Undersea Laboratory - 1.6 km, Rowell's Waterfront Park - 2 km [Playa Largo Resort & Spa, Autograph Collection](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) - **Why it's great for tailored spa getaway:** Playa Largo Resort & Spa is a luxurious retreat perfect for travellers focused on wellness, with a stellar review rating of 9.0. The full-service spa offers a range of treatments, from Swedish massages to Ayurvedic therapies, ensuring guests leave feeling refreshed and revitalised. - **Other amenities:** This upscale resort features a stunning beachfront location with private beach access and cabanas for ultimate relaxation. Guests can take advantage of the 24-hour outdoor pool, dine at the ocean-view restaurant, or unwind in the sauna and steam room. Additional offerings include kayaking, tennis courts, and a children’s club, making it a versatile choice for all guests. - **Nearby attractions:** Bluefin Rock Harbor Marina - 1 km, Baker's Cay Resort Beach - 1.4 km, North Nest Key - 3.8 km [Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://www.expedia.ca/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) - **Why it's great for tailored spa getaway:** With a review rating of 8.6, Baker's Cay Resort Key Largo is a charming destination for those looking to relax and rejuvenate. While the spa is accessible, guests can still enjoy a tranquil atmosphere and unwind in this beautiful setting. - **Other amenities:** Besides the spa, the resort provides a hot tub for relaxation, along with beachfront access and a variety of water sports including kayaking and scuba diving. Guests can enjoy casual dining at the beachfront restaurant or unwind with a drink at the poolside bar. Additional amenities include complimentary bicycles, yoga classes on-site, and a range of family-friendly activities. - **Nearby attractions:** Bluefin Rock Harbor Marina - 3.1 km, Baker's Cay Resort Beach - 0.1 km, Laura Quinn Wild Bird Sanctuary - 5.1 km ## Top Key Largo Hotel Reviews ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 10/10 Excellent "peaceful" [](https://expedia.ca/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ![Dove Creek Resort & Marina, Trademark Collection by Wyndham](//images.trvl-media.com/lodging/2000000/1190000/1186200/1186162/4ac8a422_y.jpg) ### Dove Creek Resort & Marina, Trademark Collection by Wyndham 10/10 Excellent "The stay was very calming and relaxing." [](https://expedia.ca/Key-Largo-Hotels-Dove-Creek-Resort-Marina.h1186162.Hotel-Information) ![Reefhouse Resort & Marina](//images.trvl-media.com/lodging/1000000/10000/3500/3427/af093823_y.jpg) ### Reefhouse Resort & Marina 10/10 Excellent "Everything including the spa was fantastic. " [](https://expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) ![Holiday Inn Key Largo by IHG](//images.trvl-media.com/lodging/1000000/10000/7300/7230/160ba216_y.jpg) ### Holiday Inn Key Largo by IHG 10/10 Excellent "Everything was cleaning and good working order staff was wonderful." [](https://expedia.ca/Key-Largo-Hotels-Holiday-Inn-Key-Largo.h7230.Hotel-Information) ![Marina Del Mar Resort and Marina](//images.trvl-media.com/lodging/1000000/10000/5200/5114/d42f8885_y.jpg) ### Marina Del Mar Resort and Marina 10/10 Excellent "My stay at Marina del Mar was a pleasure with helpful and friendly staff, a beautiful and comfortable room and great view from the balcony. I will definitely return and make Marina del Mar my home while in Key Largo!" [](https://expedia.ca/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information) ![Amoray Dive Resort](//images.trvl-media.com/lodging/6000000/5320000/5311400/5311313/e12ff0a0_y.jpg) ### Amoray Dive Resort 10/10 Excellent "Beautiful clean Amazing service and staff !" [](https://expedia.ca/Key-Largo-Hotels-Amoray-Resort.h5311313.Hotel-Information) ![Playa Largo Resort & Spa, Autograph Collection](//images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/489feb58_y.jpg) ### Playa Largo Resort & Spa, Autograph Collection 10/10 Excellent "Super friendly staff. Very well maintained property. Music and areas of entertainment were fantastic. Sunsets on beach priceless. Walk-in pool. Walk-in beach with aquabanas. " [](https://expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) ## Frequently asked questions ### Which hotels in Key Largo offer the best spa experiences? > Some of the best spa experiences in Key Largo can be found at [Playa Largo Resort & Spa, Autograph Collection](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information), and [Reefhouse Resort & Marina](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information). > > > > The 4.5-star Playa Largo Resort & Spa, Autograph Collection, with a 9.0 rating, offers an extensive full-service spa. Guests can enjoy a hot tub, steam room, and sauna, alongside a wide array of treatments such as Swedish massages, hot stone massages, body wraps, Ayurvedic treatments, and prenatal massages. Manicures, pedicures, and various facial treatments are also available. > > > > The 3.5-star Reefhouse Resort & Marina, rated 9.2, provides an extensive menu of body treatments. These include detoxification wraps, aromatherapy treatments, body scrubs, and deep tissue massages. The spa also features dedicated treatment rooms for massages, ensuring a focused and tranquil experience. ### How much does a spa hotel in Key Largo cost? > Enjoy staying in a spa hotel in Key Largo, with plenty of hotels from CA $408 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays. ### What are the top-rated luxury spa hotels in Key Largo? > The top-rated luxury spa hotel in Key Largo is [Playa Largo Resort & Spa, Autograph Collection](https://www.expedia.ca/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information). > > > > This 4.5-star hotel, with a 9.0 rating, offers a full-service spa with an extensive treatment menu. Guests can enjoy Swedish massages, hot stone massages, prenatal massages, and Ayurvedic treatments. The spa also provides body scrubs, body wraps, manicures, pedicures, and facial treatments. For relaxation, there is a hot tub, steam room, and sauna available. ### Is it cheaper to book a spa hotel in Key Largo with flights as part of a package deal? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect [travel package](https://www.expedia.ca/Key-Largo.d8369.Destination-Travel-Guides). ### Are there any unique spa experiences available in Key Largo? > Yes, Key Largo, Florida offers several unique spa experiences that blend island-inspired treatments with luxury and wellness. > > > > The Ocean Spa at Playa [Largo Resort](https://www.expedia.ca/Key-Largo-Hotels-Largo-Resort.h10977095.Hotel-Information) features island-infused treatments like Swedish massage, prenatal massage, and various therapies combining modern cosmetic technology with tropical wellness practices. The spa provides spacious locker rooms, a steam room, and a relaxation lounge. > > > > Lagoon Spa is a day spa offering therapeutic massages, face and body treatments, and a couples massage room. It is highly regarded for its professional service and personalised care. > > > > The Opal Spa at [Reefhouse Resort & Marina](https://www.expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) provides signature spa services inspired by its waterfront surroundings, including therapeutic massages, glow-enhancing facials, and invigorating body scrubs. The spa also offers gift cards and beauty products. > > > > The Spa at Ocean Reef Club offers a blend of new and remodelled spaces with 10 individual massage and treatment rooms, experience showers, dry sauna, steam rooms, and a relaxation lounge, known for its pampering service and luxurious amenities. ### How can I save on a spa hotel in Key Largo with Expedia? > Members always get our best prices. Find our best Key Largo spa hotel deals by joining Expedia's free travel rewards program—[One Key™](https://www.expedia.ca/welcome-one-key). As a member, you can unlock instant savings and member perks when you're logged in to your account. For a spontaneous weekend retreat, discover last-minute offers. ### Can I cancel my spa hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Key Largo for you. ## Explore a world of travel with Expedia - Lodging - More ways to book - [Adults Only Resorts & in Brickell](https://www.expedia.ca/Brickell-Miami-Hotels-Adults-Only-Resorts.0-n6240961-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Casino Hotels in Brickell](https://www.expedia.ca/Brickell-Miami-Hotels-Casino-Hotel.0-n6240961-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Brickell](https://www.expedia.ca/Brickell-Miami-Hotels-Couples-Resorts-Hotels.0-n6240961-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Brickell](https://www.expedia.ca/Brickell-Miami-Hotels-Hotel-With-Early-Check-In.0-n6240961-0-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Brickell](https://www.expedia.ca/Brickell-Miami-Hotels-Hotels-With-Hot-Tubs.0-n6240961-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - 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