Large rocks and a sandy beach with sparse vegetation.

Find hotels in Isla Santa María from CA $49

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 3 - Oct 4
Tomorrow
Oct 4 - Oct 5
Next weekend
Oct 9 - Oct 11
In two weeks
Oct 16 - Oct 18

Filter by

Star rating

Guest rating

Our top choices for Isla Santa María hotels

1. Hotel Fiesta

Hotel Fiesta
Puerto Ayora
United States
Dayana Cristina
CA $183
CA $183 total
Nov 3 - Nov 4
Hotel Fiesta

2. Hotel Ninfa

Hotel Ninfa
Puerto Ayora
United States
Rembert
CA $219
CA $219 total
Oct 4 - Oct 5
Hotel Ninfa

3. Hotel el descanso del Guia

Hotel el descanso del Guia
Puerto Ayora
United States
Keathan B.
CA $94
CA $94 total
Oct 15 - Oct 16
Hotel el descanso del Guia

4. Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos
Puerto Ayora
United States
TAKUHIRO
CA $135
CA $135 total
Nov 3 - Nov 4
Fernandina Hotel & Spa Galápagos

5. Hostal Suenos Silvestres

Hostal Suenos Silvestres
Puerto Ayora
Japan
Shunsuke
CA $63
CA $63 total
Oct 4 - Oct 5
Hostal Suenos Silvestres

6. HOTEL CROSSMAN

HOTEL CROSSMAN
Puerto Ayora
Canada
PENGFEI
CA $89
CA $89 total
Oct 4 - Oct 5
HOTEL CROSSMAN

7. Hostal el pinzon

Hostal el pinzon
Puerto Ayora
United States
Edny
CA $57
CA $57 total
Oct 12 - Oct 13
Hostal el pinzon

8. Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
Puerto Ayora
United States
Conrad
CA $730
CA $810 total
Oct 14 - Oct 15
Finch Bay Galapagos Hotel

9. Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
Puerto Ayora
United States
David
CA $361
CA $401 total
Oct 17 - Oct 18
Angermeyer Waterfront Inn

10. Hotel Cucuve

Hotel Cucuve
Puerto Ayora
United States
Sylvia
CA $254
CA $282 total
Oct 5 - Oct 6
Hotel Cucuve

11. Posada del Mar

Posada del Mar
Puerto Ayora
United States
Grace
CA $118
CA $118 total
Oct 9 - Oct 10
Posada del Mar

12. Maidith Galapagos Inn

Maidith Galapagos Inn
Puerto Ayora
United Kingdom
Thomas
CA $166
CA $166 total
Oct 4 - Oct 5
Maidith Galapagos Inn

13. Capitan Max B&B

Capitan Max B&B
Puerto Ayora
Canada
Christie
CA $110
CA $110 total
Oct 4 - Oct 5
Capitan Max B&B

14. Hotel La Casa de Judy

Hotel La Casa de Judy
Puerto Ayora
Canada
Alexandra
CA $103
CA $124 total
Oct 4 - Oct 5
Hotel La Casa de Judy

15. Galapagos Verde Azul

Galapagos Verde Azul
Puerto Ayora
Canada
sierra
CA $125
CA $125 total
Oct 4 - Oct 5
Galapagos Verde Azul

16. Hotel Santa Fe

Hotel Santa Fe
Puerto Ayora
United States
Michelle
CA $230
CA $253 total
Oct 4 - Oct 5
Hotel Santa Fe

17. El Barranco Galapagos

El Barranco Galapagos
Puerto Ayora
United States
Gloria
CA $338
CA $338 total
Oct 5 - Oct 6
El Barranco Galapagos

18. Galapagos Dreams

Galapagos Dreams
Puerto Ayora
United States
Robert
CA $112
CA $123 total
Nov 1 - Nov 2
Galapagos Dreams

19. Hostal North Seymour

Hostal North Seymour
Puerto Ayora
Canada
Craig
CA $73
CA $73 total
Oct 4 - Oct 5
Hostal North Seymour

20. Hotel Galapagos Tortuga Bay

Hotel Galapagos Tortuga Bay
Bella Vista
United States
Isabella
CA $176
CA $196 total
Nov 3 - Nov 4
Hotel Galapagos Tortuga Bay
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Isla Santa María attractions

A sea turtle swimming underwater.
Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
See properties
Two seals resting on a sandy beach with a rocky shoreline and a sunset in the background.
Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
See properties

Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

See all hotels in Isla Santa María
A beach with sea lions resting on the sand and a cruise ship in the distance.
Photo by Delen Wong

Top Isla Santa María Hotel Reviews

Hotel Cucuve

Hotel Cucuve

10/10 Excellent
"Excellent service!! A great hotel! We had a very pleasant experience. The staff were very friendly, very courteous and very helpful. I would definitely stay there again."
Taneisha 3-night trip
Posted 1 day ago
Hotel Cucuve
Hotel Coloma Galapagos

Hotel Coloma Galapagos

10/10 Excellent
"Staff was excellent. Breakfast was fresh and tasty"
DOMINIC 2-night trip
Posted 4 days ago
Hotel Coloma Galapagos
Maidith Galapagos Inn

Maidith Galapagos Inn

10/10 Excellent
"Great hotel and clean rooms. Had a comfortable stay. Breakfast was very good with a decent spread. The hotel staff was friendly and if you’re looking for a personal touch this is the hotel to stay!"
PRIYANK 2-night trip
Posted 11 days ago
Maidith Galapagos Inn
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

10/10 Excellent
"Staff was very helpful, professional and attentive. Outstanding facility and infrastructure anchored with history and legacy of Gus Angermeyer."
Tobin 4-night trip
Posted 13 days ago
Angermeyer Waterfront Inn
Posada del Mar

Posada del Mar

10/10 Excellent
"What a wonderful hotel! It is a very central location and 5 mins walk to the pier - so easy to get to your day trip meeting points quickly. It is also located between 2 delicious restaurants. The staff is nice, friendly, and accommodating. The front desk staff offered great suggestions on where to eat, ordered taxis for us, and provided clean beach towels. The breakfast is a perfect start to the day - just $8 per person. Our junior suite was spacious, clean, and comfortable. There is a mini fridge in the room and a wonderful balcony with a patio table. Highly recommend this place to all travelers."
Molly 5-night trip
Posted 3 weeks ago
Posada del Mar
Galapagos Verde Azul

Galapagos Verde Azul

10/10 Excellent
"La amabilidad y calidez del personal. Entrada y salida independiente. Habitación amplia, limpia y cómoda. La ubicación es excelente, cerca de todo."
Catalina 5-night trip
Posted 3 weeks ago
Galapagos Verde Azul
Ikala Galapagos Hotel

Ikala Galapagos Hotel

10/10 Excellent
"I highly recommend this hotel. It is very clean and staff is very friendly. The air conditioning worked great and we were very comfortable in our rooms. The rooftop restaurant is very good and is very scenic. We had breakfast there and wished we would have had dinner there too. Good location. Highly recommend."
Cheryl 1-night trip
Posted 1 month ago
Ikala Galapagos Hotel
Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel

10/10 Excellent
"I stayed in room 301 Pretty good view. 201 also has a view of the water. Breakfast was awesome every morning. Clean and close to the main avenue. The staff were excellent."
Franklin 5-night trip
Posted 1 month ago
Acacia Galapagos Boutique Hotel
Hotel La Casa de Judy

Hotel La Casa de Judy

10/10 Excellent
"This hotel was a great choice. Close enough to walk into town, great views, clean room (including bathroom) and friendly and helpful staff."
Alexandra 1-night trip
Posted 1 month ago
Hotel La Casa de Judy

More cheap stays in Isla Santa María

Carpao Lodge

Carpao Lodge

18 de febrero e isla floreana Puerto Ayora Islas Galápagos
CA $49
CA $49 total
Oct 9 - Oct 10
7/10 Good! (2 reviews)
Carpao Lodge
Hostal Costa del Pacifico

Hostal Costa del Pacifico

Avenida Tomas de Berlanga S/N Puerto Ayora Galapagos Islands
CA $61
CA $61 total
Oct 13 - Oct 14
Hostal Costa del Pacifico
Hotel Brisas Del Pacifico

Hotel Brisas Del Pacifico

General Rodriguez Puerto Ayora
CA $69
CA $69 total
Oct 4 - Oct 5
7.6/10 Good! (82 reviews)
Hotel Brisas Del Pacifico
Hostal Sir Francis Drake

Hostal Sir Francis Drake

Av. Baltra y Charles Binford Puerto Ayora Galapagos
CA $90
CA $90 total
Oct 4 - Oct 5
7.4/10 Good! (79 reviews)
Hostal Sir Francis Drake
Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel

C/ Floreana Y Matazarnos Puerto Ayora Islas Galápagos
CA $294
CA $294 total
Oct 11 - Oct 12
Acacia Galapagos Boutique Hotel
El Barranco Galapagos

El Barranco Galapagos

Los colonos Puerto Ayora Galapagos
CA $338
CA $338 total
Oct 5 - Oct 6
El Barranco Galapagos

Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Finch Bay Galapagos Hotel and Maidith Galapagos Inn. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best vacation rentals that Isla Santa María has to offer?
Villa Galapagos: This vacation home near Isla Santa María is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
What is staying in Isla Santa María like?
Travelers to Isla Santa María will find plenty to explore and enjoy. There are 216 hotels and other accommodations in larger region. Find out more about Isla Santa María.
What should I see while I'm in Isla Santa María?
Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.
What's the weather like in Isla Santa María?
The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.