Book The Best Hotels in Hillsboro, MO for 2026 from CA $82 - Fully Refundable Options

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Hillsboro

Pet friendly

Pool

Apartment

Hot tub

Cottage

Family friendly

Waterpark

Cabin

Condo

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Hillsboro hotels

A modern kitchen with a central island, built-in appliances, and a view into the dining area.

A reception desk with a modern design, a digital screen, and a sign indicating 'IHG' branding.

A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.

A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.

1. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Festus

Justen

CA $152

CA $174 total

includes taxes & fees

Sep 13 - Sep 14

A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.

A spacious lobby with a modern design, featuring a large seating area with purple and gray chairs, a patterned carpet, and a cityscape mural on the wall.

A swimming pool with lounge chairs and a view of the night sky.

A modern hotel with a prominent 'La Quinta' sign, large windows, and a well-lit entrance.

2. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Festus

Lisa-Marie

CA $115

CA $132 total

includes taxes & fees

Sep 13 - Sep 14

A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.

A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.

A hotel room with a living area, kitchenette, and a desk with a computer and chair.

A hotel lobby with a seating area, a reception desk, and a dining area.

3. Comfort Inn Festus - St Louis South

Festus

johnny

CA $101

CA $118 total

includes taxes & fees

Oct 4 - Oct 5

A laundry room with two washing machines, a change machine, and a chair.

A hotel with a brick facade, multiple windows, and a parking lot.

An indoor swimming pool with a tiled edge, surrounded by lounge chairs and a potted plant.

A hotel room with two beds, a desk with a TV, a chair, and a window with curtains.

4. Baymont by Wyndham Festus

Festus

Linda

CA $92

CA $105 total

includes taxes & fees

Sep 20 - Sep 21

5. Super 8 by Wyndham Pevely

Pevely

Steve

CA $93

CA $107 total

includes taxes & fees

Sep 20 - Sep 21

A hotel lobby with a reception desk, a revolving door, seating area with sofas, and a patterned rug.

A conference room with round tables and chairs, a patterned carpet, and a chandelier.

A hotel room with two beds, a nightstand, a lamp, and a painting on the wall.

A building with a covered entrance, columns, and a view of the sky.

6. Days Inn & Suites By Wyndham Festus

Festus

Amanda

CA $92

CA $106 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

7. Hampton Inn & Suites By Hilton Festus

Festus

"The room was clean which it should be in a new building. The bed was very comfortable. The towels, shampoo, soap were great. The pool was cold even though I was told it was heated. When I arrived to check in, the young woman that came from the back looked and acted like I was disturbing her. No greeting. She just came out and looked at me. I told her I had a reservation and gave my name. Her response was "I need an ID". I checked in right before 3 pm on Saturday. I didn't see a name tag but...

Linda

CA $144

CA $164 total

includes taxes & fees

Sep 10 - Sep 11

A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.

A modern building with a prominent entrance, large windows, and a covered parking area.

A modern indoor space with a large window, a seating area with sofas and chairs, and a dining area with tables and chairs.

A lobby with a reception desk, seating area, and large windows.

8. Pear Tree Inn St. Louis Arnold

Arnold

Susie

CA $123

CA $143 total

includes taxes & fees

Sep 13 - Sep 14

A modern living area with a sofa, armchairs, a coffee table, and a kitchen in the background.

A modern living room with a sectional sofa, a round coffee table, and large windows offering a view of the city.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A modern lobby with a reception desk, seating area, and a fireplace.

9. Best Western St. Louis Inn

St. Louis

Bryan

CA $99

CA $113 total

includes taxes & fees

Sep 13 - Sep 14

A lobby with a reception desk, blue sofas, a coffee table, and a plant display.

A spacious dining area with multiple tables and chairs, large windows, and ceiling lights.

A hotel room with a TV, a sofa, a small table, a lamp, and a carpeted floor.

A hotel room with a desk, two beds, a television, a lamp, and a cityscape painting on the wall.

10. Drury Inn & Suites St. Louis Arnold

Arnold

Bailey

CA $173

CA $200 total

includes taxes & fees

Sep 13 - Sep 14

A modern interior with hanging pendant lights, large windows, and a view of the outside.

A modern hotel lobby with a high ceiling, multiple hanging pendant lights, a reception desk with a Missouri US 66 sign, and large windows allowing natural light.

A hotel room with a flat-screen TV, a wooden cabinet, a light-colored sofa, a matching ottoman, and a small table.

A modern hotel with a covered entrance, brick facade, and a parking area.

11. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

Denise

CA $131

CA $151 total

includes taxes & fees

Sep 8 - Sep 9

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.

A modern kitchen with a sink, dishwasher, and microwave. There is a large mirror above the sink and a countertop with various items. The room has a neutral color scheme and a view of a living area with a couch and a TV.

A gym with treadmills, exercise bikes, and a mirror.

A snack display area with various packaged snacks and a refrigerated section.

12. Hampton Inn & Suites St. Louis/South I-55

St. Louis

Shannon

CA $146

CA $168 total

includes taxes & fees

Sep 20 - Sep 21

A hotel lobby with a staircase, dining area, and reception desk.

A coffee station with two coffee machines, a shelf with coffee cups, and a storage area with boxes and a thermos.

An indoor swimming pool with a tiled floor, a pool ladder, and a few chairs and tables around the pool area.

A building entrance with a black door, two potted trees, and a welcome sign.

13. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Fenton

William

CA $134

CA $155 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a desk, a chair, a dresser, and a TV.

A modern building with a brick facade and a green roof.

A dining area with wooden tables and chairs, a kitchen area with a coffee machine, and a brick wall.

A swimming pool with clear blue water, surrounded by lounge chairs and a fenced area.

14. Wingate by Wyndham St. Louis/Fenton Route 66

Fenton

Robert

CA $116

CA $134 total

includes taxes & fees

Sep 8 - Sep 9

A living room with a sofa, coffee table, and a small table with a vase. There is a window with blinds and a door in the background.

An indoor swimming pool with a 3 FT depth marker, surrounded by white walls and a ceiling with recessed lighting.

A dining area with a vending machine, a refrigerator, and a counter.

A hotel room with a bed, a desk, a chair, a couch, and a TV.

15. Super 8 by Wyndham Bonne Terre

Bonne Terre

Georgina

CA $75

CA $82 total

includes taxes & fees

Sep 14 - Sep 15

Two people in a swimming pool with colorful inflatable rings.

A hotel room with a large bed, a desk, a TV, and a view of a pool through the glass door.

A spacious lobby with a stone fireplace, a chandelier, and a staircase.

A lobby with a grand staircase, two patterned sofas, a glass coffee table, and a large mirror.

16. Holiday Inn St. Louis West Six Flags by IHG

Eureka

Rob

CA $140

CA $163 total

includes taxes & fees

Sep 21 - Sep 22

A spacious lobby with a high ceiling, a dining area, and a kitchen in the background.

An indoor swimming pool with stone flooring, white walls, and a green stripe. There are chairs and a door with a sign.

A hotel room with a bathroom, a bed, a nightstand, and a window.

A modern hotel lobby with a computer desk, a flat-screen TV, and a ceiling fan.

17. Quality Inn Near Six Flags St. Louis

Pacific

Diane

CA $136

CA $155 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a large bed, a desk, a chair, and a lamp.

A hotel reception area with a wooden reception desk, a seating area with a bench, and a wall with a geometric design and a sign that reads 'It only takes a spark.'

A hotel room with a desk, television, microwave, and air conditioning unit.

A coffee station with two types of coffee dispensers, a television, and seating with a modern design.

18. Spark by Hilton St. Louis Southwest

Valley Park

Sandra

CA $136

CA $159 total

includes taxes & fees

Sep 27 - Sep 28

A stone building with a white porch and a small garden with yellow flowers.

A dining room with a long table set for a meal, surrounded by chairs with lace covers. A piano and a bookshelf are visible in the background.

A vintage upright piano with a mirror above it, a lamp, and a floral wallpaper pattern.

A cozy seating area with wicker chairs and a coffee table, a brick wall, and a window with a view of greenery.

19. Corner George Inn Bed & Breakfast

Maeystown

John

CA $176

CA $196 total

includes taxes & fees

Sep 12 - Sep 13

A modern hotel lobby with a high ceiling, a central seating area with sofas and a coffee table, and a flat-screen TV mounted on the wall.

A hotel room with a bed, a desk with a computer, a television, a sofa, and a window with a view.

A spacious lobby with a high ceiling, a flat-screen TV mounted on the wall, and a seating area with sofas and ottomans.

A modern hotel breakfast area with a central island, buffet setup, and a large window providing a view.

20. Drury Inn & Suites Southwest St. Louis

Valley Park

Mike

CA $163

CA $191 total

includes taxes & fees

Sep 13 - Sep 14

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Hillsboro attractions

Lake Trails

Commune with nature and explore the great outdoors at Lake Trails during your travels in Hillsboro. Amble around the area's parks or visit its monuments.

See properties

Villa Antonio Winery

7.2/10 (5 reviews)

You can enjoy a tasting or tour at Villa Antonio Winery during your travels to Hillsboro. Discover the area's countryside and churches.

See properties

Sandy Creek Covered Bridge State Historic Site

8.6/10 (4 reviews)

You can find out about the history of Hillsboro with a stop at Sandy Creek Covered Bridge State Historic Site. Discover the area's sunrises and churches.

See properties

Lake Lorraine

Commune with nature and explore the great outdoors at Lake Lorraine during your travels in Hillsboro. Amble around the area's parks or visit its monuments.

See properties

Lindwell Lake

Commune with nature and explore the great outdoors at Lindwell Lake during your travels in Hillsboro. Amble around the area's parks or visit its monuments.

See properties

Boyher Lake

Commune with nature and explore the great outdoors at Boyher Lake during your travels in Hillsboro. Amble around the area's parks or visit its monuments.

See properties

Cole Lake

Commune with nature and explore the great outdoors at Cole Lake during your travels in Hillsboro. Amble around the area's parks or visit its monuments.

See properties

Daley Lake

Commune with nature and explore the great outdoors at Daley Lake during your travels in Hillsboro. Amble around the area's parks or visit its monuments.

See properties

Learn more about Hillsboro

Historic courthouse square buzzes with local shops and the Jefferson County History Centre where you'll discover fascinating regional artifacts. Nearby Mastodon State Historic Site offers prehistoric fossils and hiking trails, while Sandy Creek Covered Bridge in Goldman provides a perfect spot for picturesque photos.

See all hotels in Hillsboro

Top Hillsboro Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent

"Pleasant sent"

Best Western St. Louis-Kirkwood Route 66

10/10 Excellent

"Room was clean, bed comfortable"

The Wildwood Hotel

10/10 Excellent

"Perfect Hotel, perfect location. The town is so clean and new it seems like a movie set. Hotel was clean, rooms were great, loved the staff and the pool. Would not consider staying anywhere else when I return to the area."

The Principal Hotel

8/10 Good

"There was a musty smell in the hall on the second floor."

River City Casino & Hotel

10/10 Excellent

"Very clean rooms, great staff, easy parking very safe"

Best Western St. Louis Inn

10/10 Excellent

"The pool the room the staff were all excellent. I have no complaints. Only complaint would be the hot breakfast which was good was sausage every morning. Otherwise excellent place."

Holiday Inn St. Louis West Six Flags by IHG

10/10 Excellent

"Love love this hotel my family and my self will always come back. 😍"

Drury Inn & Suites Southwest St. Louis

10/10 Excellent

"Nice hotel"

Comfort Inn Festus - St Louis South

8/10 Good

"room was clean and the front staff was nice. place served it's purpose (stayed for only 2 nights). Not much amenitites."

More cheap stays in Hillsboro

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

CA $99

CA $113 total

Sep 13 - Sep 14

includes taxes & fees

8.4/10 Very good! (1,118 reviews)

Comfort Inn Festus - St Louis South

1303 Veterans Blvd Festus MO

CA $101

CA $118 total

Oct 4 - Oct 5

includes taxes & fees

7.8/10 Good! (1,000 reviews)

Americas Best Value Inn St. Louis South

6602 S Lindbergh Blvd St. Louis MO

CA $103

CA $118 total

Sep 13 - Sep 14

includes taxes & fees

5.4/10 (1,006 reviews)

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO

CA $123

CA $143 total

Sep 13 - Sep 14

includes taxes & fees

Best Western Plus Fenton

1680 Fenton Business Park Ct Fenton MO

CA $137

CA $159 total

Sep 14 - Sep 15

includes taxes & fees

Pinemark Inn & Suites

866 South Outer Road St. Clair MO

CA $183

CA $200 total

Sep 13 - Sep 14

includes taxes & fees

9.6/10 Exceptional! (1,005 reviews)

Hotels in Hillsboro with star rating

Frequently asked questions

What is the best area to stay in Hillsboro?

Given its size and focus, the best area to stay in Hillsboro is the central part of town, particularly around Main Street and the immediate vicinity of the Jefferson County Courthouse.This area serves as the civic and commercial heart of Hillsboro. It's where you'll find most of the local businesses, services, and community focal points. The layout is quite straightforward, with Main Street running through the centre, offering easy access to different parts of town.For visitors travelling with family, staying near the centre provides convenience. You're close to local eateries and any community parks or facilities. It makes getting around simple, reducing travel time and allowing for a more relaxed experience.Couples looking for a quiet getaway will also appreciate the central area's accessibility to local dining options and the town's general peacefulness.

When is the best time to go to Hillsboro?

The best times to visit Hillsboro are during the spring (April to early June) and autumn (September to October) months, when the weather is most pleasant for outdoor activities.Spring in Hillsboro brings comfortable temperatures, typically ranging from 15°C to 25°C, making it ideal for exploring the local parks and vineyards. The countryside around Hillsboro is particularly scenic during this time, with blooming wildflowers and lush greenery. This period is excellent for couples who enjoy scenic drives and outdoor excursions without the summer heat.Autumn also offers mild weather, with temperatures usually between 10°C and 20°C, and the added beauty of changing leaf colours. This season is superb for those who appreciate picturesque landscapes and local harvest festivals. Families might particularly enjoy apple picking or visiting pumpkin patches in the surrounding areas during this time.While summer (July and August) can be warm, with temperatures often exceeding 30°C, it's a good time for water-based activities at nearby lakes and rivers. However, if you prefer cooler weather for walking and exploring, spring and autumn are generally more comfortable.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Hillsboro.

How much is the nightly rate at a Hillsboro hotel?

Prices for hotels in Hillsboro often vary, but you can find a great deal from CA $82 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia

St. Clair Vacation Rentals

Book Hotels in Hillsboro on Expedia.com

Find hotels in Hillsboro, MO from CA $82

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Hillsboro

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Hillsboro hotels

1. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3. Comfort Inn Festus - St Louis South

4. Baymont by Wyndham Festus

5. Super 8 by Wyndham Pevely

6. Days Inn & Suites By Wyndham Festus

7. Hampton Inn & Suites By Hilton Festus

8. Pear Tree Inn St. Louis Arnold

9. Best Western St. Louis Inn

10. Drury Inn & Suites St. Louis Arnold

11. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

12. Hampton Inn & Suites St. Louis/South I-55

13. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

14. Wingate by Wyndham St. Louis/Fenton Route 66

15. Super 8 by Wyndham Bonne Terre

16. Holiday Inn St. Louis West Six Flags by IHG

17. Quality Inn Near Six Flags St. Louis

18. Spark by Hilton St. Louis Southwest

19. Corner George Inn Bed & Breakfast

20. Drury Inn & Suites Southwest St. Louis

Stay near popular Hillsboro attractions

Lake Trails

Villa Antonio Winery

Sandy Creek Covered Bridge State Historic Site

Lake Lorraine

Lindwell Lake

Boyher Lake

Cole Lake

Daley Lake

Learn more about Hillsboro

Top Hillsboro Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Best Western St. Louis-Kirkwood Route 66

The Wildwood Hotel

The Principal Hotel

River City Casino & Hotel

Best Western St. Louis Inn

Holiday Inn St. Louis West Six Flags by IHG

Drury Inn & Suites Southwest St. Louis

Comfort Inn Festus - St Louis South

More cheap stays in Hillsboro

Best Western St. Louis Inn

Comfort Inn Festus - St Louis South

Americas Best Value Inn St. Louis South

Pear Tree Inn St. Louis Arnold

Best Western Plus Fenton

Pinemark Inn & Suites

Hotels in Hillsboro with star rating

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app