A coastal landscape with clear turquoise waters, sandy beaches, and volcanic hills.

Santa Cruz Vacation Rentals

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A woman sitting on a beach facing the ocean with a sea turtle nearby.
Vacation RentalsVacation Rentals

Puerto Ayora

Puerto Ayora

Our top choices for Santa Cruz vacation rentals

An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

1. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (28 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
The price is CA $185
CA $185 total
Oct 19 - Oct 20
Torre Mar Galapagos Boutique Suites
A couple sitting on a wicker sofa outdoors, with a table between them holding breakfast items and a book titled "GALAPAGOS".

2. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is CA $159
CA $216 total
Oct 19 - Oct 20
Modern apartment with 18 feet ceilings and private terrace with view to a park
A patio with a round table and chairs, a blue umbrella, and a potted plant.

3. Suites

Suites
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (25 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is CA $107
CA $118 total
Oct 19 - Oct 20
Suites
A neatly made bed with white bedding, two bedside lamps, and a wooden headboard.

4. VILLA MICONIA

VILLA MICONIA
3.0 star property
San Cristobal
The price is CA $226
CA $226 total
Oct 19 - Oct 20
VILLA MICONIA
A kitchen with wooden cabinets, a refrigerator, and a dining table with chairs.

5. Torre Mar Galapagos Villa

Torre Mar Galapagos Villa
Puerto Ayora, Santa Cruz Island
10.0 out of 10, Exceptional, (1 review)
"We had a very nice time staying at Torre Mar. It was very conveniently located. We were 5 families...me (the mom) and my 4 kids, their spouses and 6 grandkids. Everyone had their own "suite". The advertising is a little confusing. I thought we were renting a "home", and then realized it was an apartment/hotel....but as I said, it was very nice for each family to have private space. The owner John was very friendly, although we did have some miscommunication issues, which is interesting...
United States
Betty A.
The price is CA $2,217
CA $2,526 total
Oct 19 - Oct 20
Torre Mar Galapagos Villa
A modern living room with a large table, a sofa, and a TV mounted on the wall.

6. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is CA $216
CA $313 total
Oct 26 - Oct 27
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
An aerial view of a marina with numerous boats docked, a pier with umbrellas, and a small building with a red roof.

7. Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (28 reviews)
"Great communication with host, gave us information ahead of time for laundry services and taxi. Clean and wonderful property close to everything and great views."
United States
Amanda
The price is CA $363
CA $663 total
Oct 19 - Oct 20
Galapagos Family Vacation 3 BR. Centrally located and Ocean View
A modern kitchen with a dining table, chairs, pendant lights, a refrigerator, and a large window with curtains.

8. Colmena Apartment in downtown Puerto Ayora, Santa Cruz

Colmena Apartment in downtown Puerto Ayora, Santa Cruz
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We had an excellent experience at Five minutes from the malecon Santa Cruz - Puerto Ayora. The property is brand new, very secure, and perfectly located. What truly made our stay special was our host, Gaby. She was always available, attentive, and ready to help us with anything we needed. Had we known about this place earlier, we would have booked it for our entire stay in Santa Cruz. We highly recommend this accommodation to anyone visiting the island — it’s a gem!"
United States
jacques
The price is CA $165
CA $251 total
Oct 19 - Oct 20
Colmena Apartment in downtown Puerto Ayora, Santa Cruz
A multi-story building with a curved facade, balconies with glass railings, and a staircase leading to the upper floors.

9. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is CA $98
CA $140 total
Oct 19 - Oct 20
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
A bedroom with a bed, a chair, and a view of the sea through large windows.

10. Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very good, (1 review)
The price is CA $127
CA $217 total
Oct 24 - Oct 25
Suite with spectacular ocean view, you will wake up to the sound of the sea.
A rooftop terrace with a wooden bench, a potted plant, and a view of the cityscape and mountains.

11. 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is CA $96
CA $124 total
Oct 23 - Oct 24
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
A building with a white exterior, wooden vertical elements, and a cactus plant in the foreground.

12. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is CA $115
CA $136 total
Oct 19 - Oct 20
Villa Galapagos
A rooftop terrace with a wooden bench, a potted plant, and a view of the cityscape and mountains.

13. Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
The price is CA $116
CA $144 total
Nov 1 - Nov 2
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
A seal on a sandy beach with clear blue water and a rocky outcrop in the background.

14. Comfortable and cozy Galarous Island Suite

Comfortable and cozy Galarous Island Suite
Puerto Ayora
The price is CA $121
CA $149 total
Oct 19 - Oct 20
Comfortable and cozy Galarous Island Suite
An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

15. Island Life Two-Bedroom Galapagos Casita

Island Life Two-Bedroom Galapagos Casita
Puerto Ayora
10.0 out of 10, Exceptional, (4 reviews)
"The host John was absolutely the BEST. He went above and beyond to make our stay wonderful. The house had everything one would need. "
United States
Trevor K.
The price is CA $249
CA $280 total
Oct 21 - Oct 22
Island Life Two-Bedroom Galapagos Casita
A hotel room with a bed, a wooden door with glass panels, a bathroom with a sink, and a blue tiled wall.

16. Villa Mi Caleta Inn

Villa Mi Caleta Inn
2.0 star property
Puerto Ayora
The price is CA $255
CA $293 total
Oct 20 - Oct 21
Villa Mi Caleta Inn
A hotel room with two beds, each with a wooden headboard, white and brown bedding, and a nightstand with a lamp. There are wall-mounted air conditioning units and three framed pictures depicting ocean scenes.

17. Perfect for family or friends 4 Bedroom 2 bath

Perfect for family or friends 4 Bedroom 2 bath
Puerto Ayora, Santa Cruz Island
The price is CA $558
CA $638 total
Oct 19 - Oct 20
Perfect for family or friends 4 Bedroom 2 bath
A bedroom with a bed, a wooden wardrobe, a blue laundry basket, and a window with curtains.

18. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is CA $98
CA $140 total
Oct 19 - Oct 20
TWO Bedrooms Apartment ON THE First Floor Forest View
An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

19. Island life Duplex great for groups

Island life Duplex great for groups
Puerto Ayora, Santa Cruz Island
The price is CA $453
CA $518 total
Oct 21 - Oct 22
Island life Duplex great for groups
A modern living room with a sofa, ottoman, and coffee table, large windows, and a wooden ceiling beam.

20. Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
2.0 out of 10, (1 review)
"Beware of this scam, the owner did not receive our reservstion nor the money!"
United States
Maya
The price is CA $211
CA $239 total
Oct 19 - Oct 20
Galapagos Coliving Ecuador Casa Tuna
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel el descanso del Guia

Hotel el descanso del Guia

10/10 Excellent
"All the staff were wonderful and very helpful. The breakfast was great and offered a good amount of food. Eric was the best and helped us navigate getting around the island. I would definitely stay at this hotel again."
Alesha 5-night trip
Posted 2 days ago
Hotel el descanso del Guia

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz vacation rentals we have selected for you start as low as CA $118 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.