A coastal landscape with clear turquoise waters, sandy beaches, and volcanic hills.

Santa Cruz Vacation Rentals

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Top Cities in Santa Cruz

A coastal landscape with clear turquoise waters, a sandy beach, and volcanic rocks.
Vacation RentalsVacation Rentals

Puerto Ayora

Puerto Ayora

Our top choices for Santa Cruz vacation rentals

Family Duplex, 2 Bedrooms, Private Bathroom, Garden View (Courtyard ) | Terrace/patio

Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.2 out of 10, Wonderful, (24 reviews)
"Place was spotless! Very accommodating and helpful staff."
Canada
Nicholas
The price is CA $184
CA $184 total
Jul 19 - Jul 20
Torre Mar Galapagos Boutique Suites
Exterior

Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is CA $106
CA $117 total
Jul 19 - Jul 20
Suites
Outdoor dining

Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is CA $158
CA $214 total
Jul 22 - Jul 23
Modern apartment with 18 feet ceilings and private terrace with view to a park
Luxury Apartment, Balcony | Living area

Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
The price is CA $151
CA $179 total
Jul 20 - Jul 21
Galapagos Coliving Ecuador Casa Tuna
Smart TV, books, stereo

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is CA $215
CA $306 total
Jul 19 - Jul 20
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Exterior

Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is CA $126
CA $147 total
Jul 19 - Jul 20
Villa Galapagos
1 bedroom, iron/ironing board, WiFi (free), bed sheets

Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very good, (1 review)
The price is CA $126
CA $215 total
Jul 25 - Jul 26
Suite with spectacular ocean view, you will wake up to the sound of the sea.
6 bedrooms, WiFi

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is CA $140
CA $189 total
Jul 19 - Jul 20
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Exterior

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is CA $97
CA $139 total
Jul 19 - Jul 20
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Interior

Five minutes from the Malecon Santa Cruz - Puerto Ayora.

Five minutes from the Malecon Santa Cruz - Puerto Ayora.
Puerto Ayora
The price is CA $164
CA $252 total
Jul 22 - Jul 23
Five minutes from the Malecon Santa Cruz - Puerto Ayora.
Terrace/patio

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is CA $95
CA $123 total
Jul 20 - Jul 21
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Marina

Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (26 reviews)
"Great location in Puerto Ayora! Very close to the ferry terminal and proinsular market which had everything we needed. This was the end of our trip and we were thrilled with the huge kitchen and great room for homemade family dinners. We could walk to the Darwin Research Center and the walking trail that leads to Playa Tortuga Bay. Morning coffee on the rooftop was a wonderful way to start the day. "
United States
Stephen A.
The price is CA $435
CA $747 total
Jul 29 - Jul 30
Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Interior

FAMILY SUITE in Puerto Ayora

FAMILY SUITE in Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."
United States
Nathan M.
The price is CA $280
CA $320 total
Jul 19 - Jul 20
FAMILY SUITE in Puerto Ayora
Beach

Comfortable and cozy Galarous Island Suite

Comfortable and cozy Galarous Island Suite
Puerto Ayora
The price is CA $126
CA $154 total
Jul 20 - Jul 21
Comfortable and cozy Galarous Island Suite
Property grounds

A nice place to stay with the family with spacious rooms

A nice place to stay with the family with spacious rooms
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Javier and Marí were wonderful hosts. They were gracious, helpful, and friendly. They were very accommodating and gave us a number of great recommendations of places to eat, stores to go to, and things to do. They can also set up tours as needed."
United States
Jeffrey R.
The price is CA $38
CA $72 total
Jul 20 - Jul 21
A nice place to stay with the family with spacious rooms
Private kitchen

Pinzón Apartment in Puerto Ayora

Pinzón Apartment in Puerto Ayora
Puerto Ayora
The price is CA $84
CA $125 total
Jul 25 - Jul 26
Pinzón Apartment in Puerto Ayora
Terrace/patio

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
The price is CA $115
CA $143 total
Aug 11 - Aug 12
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Outdoor dining

Galarous island apartments

Galarous island apartments
Puerto Ayora
The price is CA $140
CA $168 total
Jul 19 - Jul 20
Galarous island apartments
2 bedrooms, WiFi, bed sheets

TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is CA $97
CA $139 total
Jul 19 - Jul 20
TWO Bedrooms Apartment ON THE First Floor Forest View
Terrace/patio

¡Bienvenido a tu hogar isleño en Galápagos!

¡Bienvenido a tu hogar isleño en Galápagos!
Puerto Ayora
The price is CA $115
CA $143 total
Jul 19 - Jul 20
¡Bienvenido a tu hogar isleño en Galápagos!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel el descanso del Guia

Hotel el descanso del Guia

8/10 Good
"Clean room and friendly staff, breakfast quality needs improvement."
Mohankumar 4-night trip
Posted 2 days ago
Hotel el descanso del Guia

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz vacation rentals we have selected for you start as low as CA $72 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.