Lodging Image

Santa Cruz Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Top Cities in Santa Cruz

Our top choices for Santa Cruz vacation rentals

Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very good, (91 reviews)
"Easy to access"
United States
Dorothy
The price is CA $74
CA $74 total
Jul 9 - Jul 10
Terranova Suites

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
The price is CA $71
CA $71 total
Jul 12 - Jul 13
Equipetrol Suites Apart Hotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (109 reviews)
"Great Location"
United States
Blanca
The price is CA $65
CA $65 total
Jul 15 - Jul 16
Premium Suites Deluxe Aparthotel Equipetrol

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (102 reviews)
"Great location."
United States
Ruben
The price is CA $38
CA $38 total
Jul 23 - Jul 24
Apart Hotel Premium Suites Santa Cruz

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (2 reviews)
"Clean room, great staff "
Canada
Peter
The price is CA $49
CA $49 total
Aug 4 - Aug 5
AMERICA APARTMENTS

Samaipata Glamping

Samaipata Glamping
3.5 star property
Samaipata
The price is CA $200
CA $200 total
Jul 21 - Jul 22
Samaipata Glamping

Tranquil apartment with WiFi in Santa Cruz de la Sierra

Tranquil apartment with WiFi in Santa Cruz de la Sierra
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (2 reviews)
"Zona tranquila y todo cerca supermercados tiendas etc"
Mexico
Fabricio O.
The price is CA $57
CA $85 total
Jul 21 - Jul 22
Tranquil apartment with WiFi in Santa Cruz de la Sierra

Casa Vida

Casa Vida
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (2 reviews)
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"
Chile
FERNANDO
The price is CA $128
CA $128 total
Jul 14 - Jul 15
Casa Vida

Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (60 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
The price is CA $192
CA $192 total
Jul 9 - Jul 10
Apart Hotel Toborochi

Casa de 2 Habitaciones en zona norte

Casa de 2 Habitaciones en zona norte
Santa Cruz de la Sierra
8.0 out of 10, Very good, (1 review)
"Muy buen departamento, bien ubicado"
United States
Elva
The price is CA $55
CA $84 total
Jul 21 - Jul 22
Casa de 2 Habitaciones en zona norte

POX: 24th Floor Green Tower | Luxury and Panoramic View

POX: 24th Floor Green Tower | Luxury and Panoramic View
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Very comfortable and nice view and the super clean"
United States
Carlos
The price is CA $107
CA $149 total
Jul 16 - Jul 17
POX: 24th Floor Green Tower | Luxury and Panoramic View

Santos Apartamentos

Santos Apartamentos
3.5 star property
Santa Cruz
The price is CA $150
CA $192 total
Jul 21 - Jul 22
Santos Apartamentos

Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
The price is CA $40
CA $81 total
Jul 29 - Jul 30
Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed

VERONA Cabañas - Apartamento de 3 dormitorios 6

VERONA Cabañas - Apartamento de 3 dormitorios 6
Santa Cruz de la Sierra
The price is CA $249
CA $281 total
Jul 10 - Jul 11
VERONA Cabañas - Apartamento de 3 dormitorios 6

BEACH HOUSE 2-bedroom condo with AC, WiFi in fabulous Santa Cruz

BEACH HOUSE 2-bedroom condo with AC, WiFi in fabulous Santa Cruz
Santa Cruz de la Sierra
The price is CA $142
CA $185 total
Jul 13 - Jul 14
BEACH HOUSE 2-bedroom condo with AC, WiFi in fabulous Santa Cruz

Cabaña Renacer (cozy place, garden, nature, rustic, handmade, vintage)

Cabaña Renacer (cozy place, garden, nature, rustic, handmade, vintage)
Santa Cruz de la Sierra
The price is CA $206
CA $234 total
Jul 20 - Jul 21
Cabaña Renacer (cozy place, garden, nature, rustic, handmade, vintage)

Menacho Apartment - Mangales Blue - Norte

Menacho Apartment - Mangales Blue - Norte
Santa Cruz de la Sierra
The price is CA $32
CA $46 total
Jul 16 - Jul 17
Menacho Apartment - Mangales Blue - Norte

POX: Green Tower 16th floor : Luxury and elegance - 2H

POX: Green Tower 16th floor : Luxury and elegance - 2H
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Beautiful place, excellent location."
United States
Ruben
The price is CA $128
CA $156 total
Jul 10 - Jul 11
POX: Green Tower 16th floor : Luxury and elegance - 2H

Cozy and independent.<br>Downtown house JH.

Cozy and independent.<br>Downtown house JH.
Santa Cruz de la Sierra
The price is CA $45
CA $73 total
Jul 21 - Jul 22
Cozy and independent.<br>Downtown house JH.

Beautiful Loft in a brand new Condo, 10 minutes from business center.

Beautiful Loft in a brand new Condo, 10 minutes from business center.
Santa Cruz de la Sierra
The price is CA $43
CA $81 total
Jul 10 - Jul 11
Beautiful Loft in a brand new Condo, 10 minutes from business center.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz vacation rentals we have selected for you start as low as CA $38 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.