Lodging Image

Scott County Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Our top choices for Scott County vacation rentals

A cozy room with a wooden table and chairs, a large window, and a door with a sign.

1. Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (43 reviews)
"Super communication! . Accommodating. Nice people"
United States
JASEN
The price is CA $160
CA $199 total
includes taxes & fees
Oct 12 - Oct 13
Cozy cabins on beautiful Horseshoe Lake
A living room with a TV, a fireplace, a sofa, and wall art.

2. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (58 reviews)
"Great cute place. "
United States
Jeremy W.
The price is CA $115
CA $153 total
includes taxes & fees
Oct 7 - Oct 8
Little Blue Cottage on Spanish
A loft-style room with a wooden interior, a sofa, a table with a pumpkin decoration, and a staircase leading to an upper level.

3. Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (37 reviews)
"Great place in a beautiful location. "
United States
George B.
The price is CA $199
CA $306 total
includes taxes & fees
Oct 4 - Oct 5
Peaceful secluded cabin located near Horseshoe Lake
A small, single-story building with a wooden exterior and large windows.

4. The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is CA $160
CA $200 total
includes taxes & fees
Oct 5 - Oct 6
The Rested Duck Mallard Room
A modern living room with a wooden ceiling, a stone fireplace, a TV mounted on the wall, and a bar area with stools.

5. The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (38 reviews)
"Amazing stay! Everything was perfect."
United States
Wayne F.
The price is CA $345
CA $540 total
includes taxes & fees
Oct 4 - Oct 5
The Twisted Sassafras Treehouse
A log cabin interior with a stone fireplace, leather sofa, and a mounted deer head.

6. Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (6 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is CA $285
CA $448 total
includes taxes & fees
Oct 5 - Oct 6
Gorgeous 1856 Log Cabin, Completely Renovated
Private kitchen

7. Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly

Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Cape Girardeau
The price is CA $237
CA $334 total
includes taxes & fees
Oct 2 - Oct 3
Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Exterior

8. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is CA $220
CA $320 total
includes taxes & fees
Oct 2 - Oct 3
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
A room with a pool table, a sofa, and a dining table with chairs.

9. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Villa Ridge
10.0 out of 10, Exceptional, (3 reviews)
"The location is lovely and peaceful. The cabin is clean, comfortable and relaxing. We enjoyed the pool table and ping pong."
United States
Michelle U.
The price is CA $255
CA $375 total
includes taxes & fees
Oct 9 - Oct 10
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
A two-story house with a front porch, a small garden, and a white picket fence.

10. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (44 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is CA $254
CA $447 total
includes taxes & fees
Oct 12 - Oct 13
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Exterior

11. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...
United States
Trisha S.
The price is CA $228
CA $322 total
includes taxes & fees
Oct 2 - Oct 3
The Little Cape Lofted Cottage | Creek & Nature
A house with a backyard swimming pool, outdoor furniture, and a barbecue area.

12. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is CA $510
CA $821 total
includes taxes & fees
Oct 4 - Oct 5
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
A serene outdoor area with a pond, surrounded by trees and a grassy lawn. There are two wooden benches facing the water.

13. Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (106 reviews)
"Such a beautiful and peaceful place to stay Suzzie is a great host I stay there once or twice a year for the past several years loved every minute can’t wait to go back"
United States
Paul D.
The price is CA $192
CA $358 total
includes taxes & fees
Oct 8 - Oct 9
Charming cottage overlooking Lake Acre
A hallway with white doors, a ceiling light, and a floor with a wood-like pattern.

14. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is CA $136
CA $254 total
includes taxes & fees
Oct 20 - Oct 21
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
A bedroom with a bed, a bottle of J. Roget champagne, two glasses, and a plate with snacks.

15. The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is CA $178
CA $283 total
includes taxes & fees
Oct 5 - Oct 6
The Cottage, Rusted Route Farms
Ground floor of the Euro

16. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is CA $220
CA $314 total
includes taxes & fees
Oct 2 - Oct 3
The Little Château | Woodland Escape
A modern kitchen with a large island, white cabinetry, and a brick accent wall.

17. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is CA $285
CA $448 total
includes taxes & fees
Oct 5 - Oct 6
Beautifully Renovated Farmhouse in Jackson, MO
Exterior

18. Purple Tiny House with Fire pit & Nature

Purple Tiny House with Fire pit & Nature
Cape Girardeau
The price is CA $196
CA $288 total
includes taxes & fees
Oct 2 - Oct 3
Purple Tiny House with Fire pit & Nature
A compact kitchen with wooden cabinets and a dining area with a table and chairs.

19. Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
9.8 out of 10, Exceptional, (14 reviews)
"We were only there for 1 night for a business trip but it was perfect for our stay. Very clean and comfortable and the host was onsite to welcome us. She even gave us a tip on the best place nearby for dinner that we will be going to any time we can in the future. I would gladly stay here again for future trips."
United States
Terry H.
The price is CA $214
CA $254 total
includes taxes & fees
Oct 19 - Oct 20
Villa B offers peace and quiet with beautiful views of the countryside.
A kitchen with wooden cabinets, a black refrigerator, a microwave, a stove, and a ceiling fan. There are three stools at the island.

20. Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (38 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is CA $214
CA $254 total
includes taxes & fees
Oct 19 - Oct 20
Relax in the country at Countryside Villas! - Villa A
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Scott County Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"EVERYONE was EXTREMELY FRIENDLY"
Rex 1-night trip
Posted 20 hours ago
Drury Inn & Suites Sikeston, MO

Find out more about Scott County

Everything you need to know about Scott County vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Scott County vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Scott County vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Scott County vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Scott County. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Scott County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Scott County vacation rentals we have selected for you start as low as CA $153 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Scott County rentals

At Expedia, we put the best Scott County vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Scott County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Scott County vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Scott County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.