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Cheap Flights to Defiance , MO from CA $122

View CA $122 flight on Wed, Oct 7, 2026Opens in a new window

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How much is the cheapest flight to Defiance?

Prices were available within the past 7 days and start at CA $122 for one-way flights and CA $272 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
American Airlines
Delta
United
Air Canada

Find the cheapest month to fly from Columbus (CMH) to St. Louis (STL)

From CA $255 - CA $1,105 per traveller.

Frequently asked questions

What is the name of Defiance's airport?
Book a flight to Defiance and you'll be touching down at Lambert-St. Louis Intl. Airport (STL).
How far is Lambert Field from central Defiance?
Long commutes don't have to be stressful if you consider your options ahead of time. Downtown Defiance is 40 kilometres from STL, so it's smart to know how you'll get into the city before you touchdown.
What airport is best to fly into Defiance?
STL is the main airport in Defiance. Before you head there, it's a wise idea to research a thing or two about it. It sits about 40 kilometres from the downtown area.
How many airlines fly to Defiance?
There are 12 air carriers that jet into Defiance from 61 airports around the world.
Which airlines fly to Defiance?
United Airlines and American Airlines fly often into Defiance. Catching a United Airlines flight from Chicago is one of the most popular ways to get there.
How many nonstop flights are there to Defiance?
Organizing an unforgettable Defiance escape is a walk in the park when there are 1,206 nonstop flights each week to choose from.
Where are the most popular flights to Defiance departing from?
Travellers frequently set off from Chicago, Dallas and New York airports when going to Defiance.
How long is the flight to Defiance Airport?
Where you depart from determines how much of the in-flight entertainment you'll get to enjoy. From Chicago to Defiance, the average flight time is 1 hour and 22 minutes. From Dallas it's more like 1 hour and 43 minutes, and from New York it's 3 hours and 1 minute.
How to book the cheapest flight to Defiance?
We've all come across those jet-setters who somehow manage to nab extremely cheap plane tickets wherever they go. Want to know how to do it for your Defiance vacation? Don't wait until the last minute to lock in your flight. Also, look around online and compare your options. If your destination has several airports, you may be able to pick up an excellent deal by flying into a less busy terminal. Finally, another simple way to save some cash is be ready to book at a moment's notice. If you see a fantastic bargain, don't hold off — grab it while you've got the chance.
Do you have any tips for my flight to Defiance?
Depending on where you're coming from, your flight to Defiance could be a piece of cake or it could go on forever. Below are some handy hints that will help you start your next big adventure on a positive note. What to pack in your hand luggage:
  • It's simple — first, put in your passport, official ID, bank cards and daily medications. Next, you'll want some extra in-flight entertainment to help pass the time. A juicy book and a phone crammed with your favourite movies are some wonderful options. If you plan to take a quick snooze, a quality neck pillow and a pair of earplugs will also be useful. Finally, leave some space for a toothbrush and some facial wipes to ensure you hop off the plane feeling fresh as a daisy.
Do not pack the following items in your hand luggage:
  • Leave all your full-sized bottles of shampoo and conditioner in your checked luggage. Any liquids or gels in your carry-on bag larger than 3.4 ounces (100 millilitres) will be confiscated by security. Sharp objects, like your precious Swiss Army knife, and dangerous products which are flammable or explosive, such as flares, chemicals agents and strong acids, are also not allowed.
What to wear on a flight:
  • The aisles of a plane aren't the place for a fashion parade. Wear layers and go for shoes that are flat, enclosed and easy to remove.
  • The result of sustained periods of immobility, deep vein thrombosis (DVT) is a blood clot condition that can affect some passengers during long-haul flights. Reduce the risks by staying hydrated, keeping your feet and legs moving and wearing compression socks or tights.
How to get through airport security fast when flying to Defiance?
Being organized before you get to the airport will make your getaway to Defiance quick and painless. Read through our useful tips and tricks for a speedy journey past security:
  • First things first. Your travel ID and boarding pass will need to be shown to airport security. Keep them within easy reach so you don't hold up the queue.
  • Your jacket, belt, keys and other small items, like your headphones, will be required to go through the X-ray machine. Make your life easier by removing them before your turn arrives.
  • Your electronic gadgets like laptops and phones will also have to go through the machine to be scanned. Don't worry though, you'll be back online before you know it.
  • Remember to remove liquids and gels from your carry-on bag. They usually need to be sent through the X-ray separately. Each item should be in a container no larger than 3.4 ounces (100 millilitres) and everything must fit in a single quart-size (one litre), clear zip-lock bag.
  • Choosing your footwear wisely can save you several minutes. Boots and bulky shoes are often required to be removed and X-rayed separately. Slip-on sneakers usually aren't.
  • Avoid taking prohibited items in your carry-on bag. If you have any sharp or pointed objects, put them in your checked suitcase. They won't be allowed on board.

Book with confidence

Find Your Flights to Defiance STL

Cheap flights to Defiance (STL)

Get started finding a cheap flight to Defiance on Expedia by either choosing a deal on this page or using the search bar to enter your travel dates, origin airport, and whether you want a roundtrip or one-way airfare. You can filter for flexibility, number of stops, airline, and departure/arrival times to find the best flight for you.

We recommend using the ‘Flexible Dates’ calendar at the top of the page to see the price of plane tickets on the surrounding dates. This allows you to pick the cheapest days to fly if your trip allows flexibility and score cheap flight deals to Defiance.

Roundtrip prices range from CA $272 - CA $481, and one-ways Defiance start as low as CA $122.

Be aware that choosing a non-stop flight can sometimes be more expensive while saving you time. And routes with connections may be available at a cheaper rate.

Airlines that fly to Defiance (STL)

You have several options for which airline you choose to travel with to Defiance. There are 10 airlines flying into STL: American Airlines, Southwest Airlines, United, Delta, Alaska Airlines, Air Canada. 

Cheap plane tickets may be available from different airlines at different times and with unique terms. It’s best to understand the details of each airline’s offer before judging its value.

For example, if you plan to check a bag or bring a carry-on, check whether the cheap airfare deal includes a baggage allowance. If not, verify whether the baggage fee is higher than the difference of other airline plane ticket deals offering free checked/carry-on baggage in exchange for a slightly higher airfare. 

Additionally, your preferred frequent flyer membership programmes may influence your choice of cheap airline. Expedia allows you to enter your membership numbers during checkout to earn points from your airline and Expedia Rewards—all while getting a great deal and planning all your travel on one online platform.

Find the best deals

At Expedia, we source many flight deals from multiple providers, so you can easily find the best deals that are right for you. A great strategy for getting the best deals can be to make sure you book and travel at optimal times. Airfare to Defiance (STL) varies throughout the year based on seasonal demand. You’ll see the lowest rates for roundtrips to STL in September and in October for one-ways.

Cancellation & flexibility

To change or cancel eligible flights, go to ‘My Trips’ and navigate to your itinerary. If you booked within the last 24 hours, you might be able to cancel your flight for free. Learn more about flight changes or cancellations from our customer service portal. Some plane tickets are available with no change fees, which you can filter for during your search.

Find Your Flights to Defiance STL

Travel information

Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Destination city name
St. Louis
Roundtrip price
CA $272

Trending flights to Defiance

Prices were available within the past 7 days and start at CA $122 for one-way flights and CA $272 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines

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