5 Stars Hotels in Key West, Florida from CA $163

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Top Key West 5 Star Hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Key West

Stroll Duval Street's colourful shops and bars before catching the sunset celebration at Mallory Square with local performers. Explore Hemingway's historic home where six-toed cats roam freely, then snorkel the vibrant coral reefs just offshore.

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Frequently asked questions

What are the best 5-star hotels in Key West?
If you're seeking a 5-star experience, Casa Marina Key West, Curio Collection by Hilton offers one of the best of them according to reviews by our customers. Check in to this Key West getaway and look forward to amazing guest services, luxurious guest rooms and superior facilities.
How much does it cost to stay in a 5-star hotel in Key West?
How much you pay for a 5-star hotel in Key West depends on factors like when you plan to go and the length of your stay. Our insider tip for scoring an awesome deal? Use our pricing filters to compare the available options for your selected dates.

  • Search for the lowest price per night from CA $163

What makes a hotel 5 stars in Key West?
In Key West, a hotel must offer a certain amount of upscale amenities to earn a 5-star rating. These may include saunas and spas, on-site gyms, gourmet restaurants, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their superior standard of service. You can look forward to things like concierge services, nightly turn-down services and in-room massage. Some may also offer additional touches such as welcome gifts.