5 Stars Hotels in Duck Key, Marathon from CA $197
Change your mind
Be picky
Check availability on Duck Key 5 Star Hotels
Top Duck Key 5 Star Hotels

Isla Bella Beach Resort & Spa
Isla Bella Beach Resort & Spa
Explore similar 4-star hotels

Hawks Cay Resort
Learn more about Duck Key
Kayak through mangrove tunnels and spot colourful fish in the crystal-clear waters surrounding this tiny island paradise. Unwind at Hawks Cay Resort's saltwater lagoon or take a short trip to Marathon for the Turtle Hospital's educational tours.

Top Duck Key Hotel Reviews

Isla Bella Beach Resort & Spa
Find out more about Duck Key
Find out more about Duck Key
Five Star Hotels in Duck Key
There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Duck Key so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Duck Key and get ready to be pampered like never before.
Get a Great Deal on 5-Star Hotels in Duck Key
Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.
Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.
Make Your Escape to Duck Key
The results are in, and Duck Key 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Duck Key! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Duck Key today and settle down in the lap of luxury tomorrow.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Duck Key Hotels by Star Rating
Hotels near Popular Duck Key Attractions
- Hotels near Everglades National Park
- Hotels near Sombrero Beach
- Hotels near Seven Mile Bridge
- Hotels near Fiesta Key
- Hotels near Vaca Key
- Hotels near Curry Hammock State Park
- Hotels near Anne's Beach
- Hotels near Coco Plum Beach
- Hotels near Sunset Park Beach
- Hotels near Bud n' Mary's Dive Center
- Hotels near Long Key State Park
- Hotels near Pigeon Key
- Hotels near Robbie’s of Islamorada
- Hotels near Little Conch Key
- Hotels near Captain Hooks Marina and Dive Center
- Hotels near Florida Keys Country Club
- Hotels near Sunset Drive Beach
- Hotels near Crane Point Museum and Nature Center
More Hotel Options in Duck Key
- Adults Only Resorts & Hotels in Duck Key
- Beach Hotel in Duck Key
- Business Hotels in Duck Key
- Cheap Hotels in Duck Key
- Family Hotels in Duck Key
- Golf Hotels in Duck Key
- Honeymoon Resorts and Hotels in Duck Key
- Hotel Wedding Venues in Duck Key
- Hotels & Resorts for Couples in Duck Key
- Hotels with Balconies in Duck Key
- Hotels with Bar in Duck Key
- Hotels with Childcare in Duck Key
- Hotels with Free Parking in Duck Key
- Hotels with Hot Tubs in Duck Key
- Hotels with Tennis Courts in Duck Key
- Hotels with Waterslides in Duck Key
- Hotels with Wifi in Duck Key
- Hotels with a Pool in Duck Key
- Lake Hotels in Duck Key
- Luxury Hotels in Duck Key
- Oceanfront Hotels in Duck Key
- Romantic Hotels in Duck Key
- Scuba Diving in Duck Key
- Shopping Hotels in Duck Key
- Spa Hotels in Duck Key
Explore more hotels
- Rainbow Bend Resort
- Coconut Cay Resort & Marina
- Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
- Tranquility Bay Beachfront Hotel and Resort
- Yacht Haven Marina
- La Siesta Resort & Villas
- Banana Bay Resort & Marina
- Captain Pips Marina & Hideaway
- Hampton Inn Marathon - Florida Keys
- Cabins at Bonefish Bay
- Kingsail Resort
- Grassy Flats Resort & Beach Club
- Tropical Cottages
- Breezy Palms Resort
- Glunz Ocean Beach Hotel & Resort
- Seascape Resort & Marina
- Skipjack Resort & Marina
- Pines & Palms Resort
- Gulf View Waterfront Resort
- Floating Sea Cove Resort & Marina
More ways to book
Expedia's Latest Trends
- Best Hotels in Amelia Island
- International Drive District Cheap Hotels
- Hotels in International Drive District
- Best Hotels in Las Vegas
- Hotels near Frankfurt Airport
- DoubleTree by Hilton Montreal
- The Westin Ottawa
- All Inclusive Resorts and Hotels in Greece
- Holiday Inn Express Hotel & Suites Calgary S-Macleod Trail S by IHG
- International Drive District Hotels with Free Airport Shuttle
- Hotels in Downtown Vancouver
- Best Hotels in The Blue Mountains