Title: 5 Stars Hotels in Key West, Florida from CA $319 - Find Cheap Key West Hotels With 5 Stars | Expedia.ca [Key West Travel Guide](https://expedia.ca/Key-West.dx1187)[Hotels in Key West](https://expedia.ca/Key-West-Hotels.d1187.Travel-Guide-Hotels)[Vacation Rentals in Key West](https://expedia.ca/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)[Flights to Key West](https://expedia.ca/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights)[Things to do in Key West](https://expedia.ca/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)[Key West Car Rentals](https://expedia.ca/Car-Rentals-In-Key-West.d1187.Car-Rental-Guide)[Key West Vacation Packages](https://expedia.ca/Key-West.d1187.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/497000/497918-south-beach-fm.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Key West, Florida from CA $319 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Key West 5 Star Hotels Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=1187&startDate=2025-09-27&endDate=2025-09-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=1187&startDate=2025-09-28&endDate=2025-09-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=1187&startDate=2025-10-03&endDate=2025-10-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=1187&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Key West 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Key-West-Hotels.s50-0-d1187.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Key-West-Hotels.s50-0-d1187.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Key West. ![Hyatt Centric Key West Resort and Spa](https://images.trvl-media.com/lodging/1000000/10000/1000/901/0b72a249_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Centric Key West Resort and Spa 601 Front St, Key West, FL CA $277 CA $403 total Sep 28 - Sep 29 includes taxes & fees 8.8/10 Excellent! (1,019 reviews) [](https://expedia.ca/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information) ![Oceans Edge Key West Resort, Hotel & Marina](https://images.trvl-media.com/lodging/17000000/16210000/16203000/16202992/3a4457a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Oceans Edge Key West Resort, Hotel & Marina 5950 Peninsular Avenue, Key West, FL CA $212 CA $319 total Oct 28 - Oct 29 includes taxes & fees 8.8/10 Excellent! (1,730 reviews) [](https://expedia.ca/Key-West-Hotels-Oceans-Edge-Key-West-Resort.h16202992.Hotel-Information) ![Southernmost Beach Resort and Guesthouses](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/026f10af_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Southernmost Beach Resort and Guesthouses 1319 Duval Street, Key West, FL CA $246 CA $371 total Oct 13 - Oct 14 includes taxes & fees 8.6/10 Excellent! (2,768 reviews) [](https://expedia.ca/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information) Still don't see what you're looking for? [See all properties in Key West.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=1187&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=1187&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=1187&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=1187&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=1187&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=28%2F09%2F2025&endDate=29%2F09%2F2025®ionId=1187&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Key West Located at the southernmost tip of Florida, this sun-drenched, fun-loving island encourages visitors to leave their worries behind and embrace relaxation. [See all hotels in Key West](https://www.expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12&adults=2®ionId=1187) ![](https://mediaim.expedia.com/destination/1/c4f5fbe406cfa98c536b7a56abbbef4c.jpg?impolicy=fcrop&w=900&h=495&p=1&q=high) ## Top Key West Hotel Reviews ## Find out more about Key West Luxury is the name of the game at the best 5 Stars hotels in Key West. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Key West 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them. Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Key West hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Key West without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Key West. ## Frequently asked questions ### What are the best 5-star hotels in Key West? > If you're seeking a 5-star experience, [Casa Marina Key West, Curio Collection by Hilton](https://www.expedia.ca/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information) offers one of the best of them according to reviews by our customers. Check in to this Key West getaway and look forward to amazing guest services, luxurious guest rooms and superior facilities. ### How much does it cost to stay in a 5-star hotel in Key West? > How much you pay for a 5-star hotel in Key West depends on factors like when you plan to go and the length of your stay. Our insider tip for scoring an awesome deal? Use our pricing filters to compare the available options for your selected dates. > > > > - Search for the lowest price per night from CA $319 ### What makes a hotel 5 stars in Key West? > In Key West, a hotel must offer a certain amount of upscale amenities to earn a 5-star rating. These may include saunas and spas, on-site gyms, gourmet restaurants, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their superior standard of service. You can look forward to things like concierge services, nightly turn-down services and in-room massage. 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[Lake Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Lake-Hotels.0-n6281809-0-tLakeHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Oceanfront-Hotels.0-n6281809-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Pet-Friendly-Hotel.0-n6281809-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Remington Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Remington.0-n6281809-0--bRemington.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Romantic-Hotel.0-n6281809-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Scuba Diving Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Scuba-Diving-Vacations.0-n6281809-0-tscubadivingvacations.Travel-Guide-Filter-Hotels) - [Spa Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Spa-Hotel.0-n6281809-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Waterpark-Hotels.0-n6281809-0-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Key West Historic District](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels-Wyndham-Hotels.0-n6281809-0--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Key West Historic District Hotels](https://www.expedia.ca/Key-West-Historic-District-Key-West-Hotels.0-n6281809-0.Travel-Guide-Filter-Hotels) - [Hotels near Key West Lighthouse and Keeper's Quarters Museum](https://www.expedia.ca/Key-West-Lighthouse-And-Keepers-Quarters-Museum-Hotels.0-l501383-0.Travel-Guide-Filter-Hotels) - [Truman Annex Hotels](https://www.expedia.ca/Truman-Annex-Key-West-Hotels.0-n553248635976473207-0.Travel-Guide-Filter-Hotels) - [Duval Street](https://www.expedia.ca/Duval-Street-Key-West-Historic-District.d6068616.Vacation-Attraction) - [Visit Bahama Village](https://www.expedia.ca/Key-West-Bahama-Village.dx553248621533115696) - [Visit Downtown Key West](https://www.expedia.ca/Key-West-Downtown-Key-West.dx553248635976470405) - [Key West Historic District Vacations](https://www.expedia.ca/Key-West-Historic-District.d6281809.Destination-Travel-Guides) - [Visit Historic Seaport](https://www.expedia.ca/Key-West-Historic-Seaport.dx553248635976383502) - [Visit Key West Historic District](https://www.expedia.ca/Key-West-Key-West-Historic-District.dx6281809) - [Key West Lighthouse and Keeper's Quarters Museum](https://www.expedia.ca/Key-West-Lighthouse-And-Keepers-Quarters-Museum-Old-Town-Key-West.d501383.Vacation-Attraction) - [Book 5 Star Hotels in Key West on Expedia.com](https://www.expedia.com/5Star-Key-West-Hotels.s50-0-d1187.Travel-Guide-Filter-Hotels)