Photo by Michele Wallace
Wise Vacation Rentals
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Next weekend
In two weeks
In one month
In two months
Browse Select Wise Vacation Homes

Charming 2-bedroom house in Wise, Virginia
Charming 2-bedroom house in Wise, Virginia
10.0 out of 10, Exceptional, (3)
The price is CA $124
CA $243 total
includes taxes & fees
Aug 8 - Aug 9

Newly restored Victorian home on Main Street.
Newly restored Victorian home on Main Street.
6.0 out of 10, (2)
The price is CA $136
CA $491 total
includes taxes & fees
Aug 11 - Aug 12

Bed and Biscuit Inn Pet friendly ! Near Kingdom come park & Pine mtn.
Bed and Biscuit Inn Pet friendly ! Near Kingdom come park & Pine mtn.
9.8 out of 10, Exceptional, (6)

Close to town, the college and a beautiful serene surrounding
Close to town, the college and a beautiful serene surrounding
9.6 out of 10, Exceptional, (51)

Nottingham Turret Rm w Queen Bed, Near UVaWise & Main St, Private Detached Bath
Nottingham Turret Rm w Queen Bed, Near UVaWise & Main St, Private Detached Bath
10.0 out of 10, Exceptional, (12)
The price is CA $161
CA $210 total
includes taxes & fees
Aug 17 - Aug 18

Whitesburg Vacation Home w/ Screened Porch
Whitesburg Vacation Home w/ Screened Porch
9.6 out of 10, Exceptional, (7)

Charming 1-bedroom house in welcoming Big Stone Gap Virginia!
Charming 1-bedroom house in welcoming Big Stone Gap Virginia!
10.0 out of 10, Exceptional, (2)

360 Degree Mountain View
360 Degree Mountain View
9.8 out of 10, Exceptional, (8)
The price is CA $137
CA $433 total
includes taxes & fees
Aug 12 - Aug 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Wise Hotel Reviews

The Inn at Wise
10/10 Excellent
Find out more about Wise
Find out more about Wise
Wise Vacation Homes information
Number of reviews | 96 |
---|---|
Accommodation | 15 Vacation Homes |
Lowest Price | CA $124 |
Highest Price | CA $161 |
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top Vacation Homes in Other Destinations
More Accommodation Types in Wise
All Accommodation Types
Be inspired: Top Vacation Homes destinations in 2025
- Orlando Vacation Homes
- Florida Vacation Homes
- Kissimmee Vacation Homes
- Hawaii Vacation Homes
- Costa Rica Vacation Homes
- Walt Disney World® Vacation Homes
- Palm Springs Vacation Homes
- Naples Vacation Homes
- Victoria Vacation Homes
- Kelowna Vacation Homes
- Toronto Vacation Homes
- Las Vegas Vacation Homes
- Vancouver Vacation Homes
- Mexico Vacation Homes
- Phoenix Vacation Homes
- Fort Lauderdale Vacation Homes
- Davenport Vacation Homes
- Myrtle Beach Vacation Homes
- Los Angeles Vacation Homes
- Cape Coral Vacation Homes
More ways to book
Expedia's Latest Trends
Hotels
- Virginia Beach Oceanfront Hotels
- Hotels in Fredericksburg
- Hotels in Emporia
- Hotels in Hillsville
- Virginia Beach All Inclusive Resorts and Hotels
- Hotels in Williamsburg
- Hotels in Wytheville
- Virginia Beach Hotels with Kitchenettes
- Hotels in Harrisonburg
- Hotels in Charlottesville
- Hotels in Woodbridge
- Hotels in Winchester
- Hotels in Alexandria
- Hotels in Roanoke
- Hotels in Virginia Beach
Flights
Vacation Rentals
General