Title: Book the Best Upstate South Carolina Hotels with Early Check-in in 2026 from CA $110 | Expedia.ca [Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![The view from Caesars Head after a storm](https://images.trvl-media.com/place/553248621532656715/293b23c7-6024-49ab-80cb-4ee292c1b5a3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michelle Hendrix # Find Hotels with Early Check-in in Upstate South Carolina, SC from CA $110 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina Hotels with Early Check-in Tonight [Jan 7 - Jan 8](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-07&endDate=2026-01-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 8 - Jan 9](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-08&endDate=2026-01-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina hotels with express check-in ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b840578e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/8238721d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Greenville Golf Resort & Conference Center [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) Greenville 9.0/10 Wonderful (1014) "Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kurt CA $130 CA $143 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/31a466c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/00a58c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/e1cb09dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/8cef3eda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Anderson by IHG [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Anderson.h5547.Hotel-Information) Anderson 8.6/10 Excellent (385) "Convenient location to I-85, quiet with nice parking area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $145 CA $161 total includes taxes & fees Jan 10 - Jan 11 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Anderson.h5547.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/a7e2d124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/39e12856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/91f2c765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/1000000/130000/120500/120431/1c93baf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Simpsonville [](https://www.expedia.ca/Simpsonville-Hotels-Hampton-Inn-Simpsonville.h120431.Hotel-Information) Simpsonville 8.8/10 Excellent (596) "The hotel staff is excellent here. The rooms were very clean and very well furnished the bedding, and the bed itself was as comfortable as I remember in a while." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $141 CA $166 total includes taxes & fees Jan 23 - Jan 24 [](https://www.expedia.ca/Simpsonville-Hotels-Hampton-Inn-Simpsonville.h120431.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/2c84c92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) Seneca 9.4/10 Exceptional (205) "Nice hotel by the lake" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $173 CA $190 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d93f55e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d45e119a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/56ecee45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/799eeb33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Greer Greenville, SC [](https://www.expedia.ca/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information) Greer 9.6/10 Exceptional (421) "Very nice hotel! Clean! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $192 CA $209 total includes taxes & fees Jan 9 - Jan 10 [](https://www.expedia.ca/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/3665dfba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/a1d7ed0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/w3997h2667x0y0-e203724b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Greenville Downtown [](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1000) "Room was very clean, the staff was great and the location was perfect!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $168 CA $184 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/800/708/w2678h1966x0y0-e3e18b8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/2fe691fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/10000/800/708/f720c9db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Greenville Airport Inn [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) Greenville 7.8/10 Good (1007) "Good hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) magadan CA $100 CA $110 total includes taxes & fees Jan 10 - Jan 11 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/3ff858d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/4bac382e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/015cc42b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/59000000/58950000/58945900/58945857/561d946e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Greenville Mauldin [](https://www.expedia.ca/Greenville-Hotels-Courtyard-By-Marriott-Greenville-Mauldin.h58945857.Hotel-Information) Greenville 9.0/10 Wonderful (307) "Courteous and friendly front desk" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bernard CA $144 CA $158 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Greenville-Hotels-Courtyard-By-Marriott-Greenville-Mauldin.h58945857.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/f18cfd05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/816f82a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/8ea6d425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/acae25f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Easley/Greenville [](https://www.expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) Easley 7.4/10 Good (762) "Easy access from the highway lot of restaurants around the hotel and staff is very friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) brian CA $104 CA $115 total includes taxes & fees Jan 9 - Jan 10 [](https://www.expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/b9f7d424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/2b1823e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/94802071.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/daea4e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Greenville Downtown [](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) Greenville Downtown 9.6/10 Exceptional (1001) "Great spot and beautiful hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $173 CA $190 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-22&endDate=2026-01-23®ionId=6057939&adults=2&property_amenities_group_explore=express_checkin&sort=RECOMMENDED&openPlayBack=true) ## Top Upstate South Carolina Hotel Reviews ![Best Western Greenville Airport Inn](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f_y.jpg) ### Best Western Greenville Airport Inn 10/10 Excellent "It was clean nice peaceful and quiet no disturbance rest well great" [](https://expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels with a Pool in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina ](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - 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