Title: Hotels by Red Lion in Texas Medical Center from CA $93 | Expedia.ca [Texas Medical Center Travel Guide](https://expedia.ca/Houston-Texas-Medical-Center.dx6143504)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Texas Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Texas-Medical-Center.d6143504.Car-Rental-Guide)[Texas Medical Center Vacations](https://expedia.ca/Texas-Medical-Center.d6143504.Destination-Travel-Guides) ![Houston_TexasChildrensHospital_553248635389801905_9](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2026-01-30&endDate=2026-01-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Texas Medical Center Red Lion ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32670000/32666900/32666835/9bd44127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/33000000/32670000/32666900/32666835/4e762b04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Street view](https://images.trvl-media.com/lodging/33000000/32670000/32666900/32666835/12f86f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32670000/32666900/32666835/9eafa368.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn & Suites NE Houston Downtown I-610 [](https://www.expedia.ca/Houston-Hotels-Americas-Best-Value-Inn-Suites-Northeast-Houston-I-610.h32666835.Hotel-Information) Northside 8.6/10 Excellent (644 reviews) "I always enjoy my stay . Preciate it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DeJah CA $86 CA $101 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Houston-Hotels-Americas-Best-Value-Inn-Suites-Northeast-Houston-I-610.h32666835.Hotel-Information) ![Blackout drapes, WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71140000/71134200/71134178/de9c27be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom](https://images.trvl-media.com/lodging/72000000/71140000/71134200/71134178/ee47ce5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71140000/71134200/71134178/ef4fc550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/72000000/71140000/71134200/71134178/419e8938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Signature Inn North Houston District [](https://www.expedia.ca/Houston-Hotels-Signature-Inn-Houston-Greenspoint.h71134178.Hotel-Information) Houston 6.4/10 (56 reviews) "The Customer Services is very nice, King and helpfull people" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $81 CA $93 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Houston-Hotels-Signature-Inn-Houston-Greenspoint.h71134178.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17500/17447/50c6aa12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17500/17447/91d75487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/17500/17447/2d57fbde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/17500/17447/ec3856be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Signature Inn Houston Galleria [](https://www.expedia.ca/Houston-Hotels-Signature-Inn-Houston-Galleria.h17447.Hotel-Information) Woodlake - Briar Meadow 8.4/10 Very good (550 reviews) "Everything went smooth and hotel staff were good would stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kiely CA $98 CA $114 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Houston-Hotels-Signature-Inn-Houston-Galleria.h17447.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13®ionId=6143504&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FTexas-Medical-Center-Houston-Hotels-Red-Lion.0-n6143504-0--bRedLion.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FTexas-Medical-Center-Houston-Hotels-Red-Lion.0-n6143504-0--bRedLion.Travel-Guide-Filter-Hotels) ## Top Texas Medical Center Hotel Reviews ![Hotel Zaza Houston Museum District](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/47c5ade4_y.jpg) ### Hotel Zaza Houston Museum District 10/10 Excellent "All aspects of Hotel Zaza are consistently excellent. Rooms are clean & comfortable. Staff is friendly & accommodating regardless of how busy they are. Excellent restaurant. Highly recommended " [](https://expedia.ca/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![The Westin Houston Medical Center/Museum District](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387_y.jpg) ### The Westin Houston Medical Center/Museum District 10/10 Excellent "Wonderful hotel to stay. Clean rooms, smells great, great staff, food, amenities, and relaxing " [](https://expedia.ca/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) ![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg) ### The Royal Sonesta Houston Galleria 10/10 Excellent "My welcome was the best part: I was told, “welcome home! You’re going to be with us for a while!” It was so genuine and sweet. My room was comfortable, quiet and the location was ideal. " [](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 10/10 Excellent "Room was very clean and spacious! They promptly brought us linens for the couch bed and extra towels when we called!" [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![Hilton Americas-Houston](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Clean room, Nice staff" [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![DoubleTree by Hilton Hotel Houston - Greenway Plaza](https://images.trvl-media.com/lodging/1000000/30000/20200/20177/682ca680_y.jpg) ### DoubleTree by Hilton Hotel Houston - Greenway Plaza 10/10 Excellent "Great view of the city. Perfect location. " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Houston-Greenway-Plaza.h20177.Hotel-Information) ![Thompson Houston, by Hyatt](https://images.trvl-media.com/lodging/94000000/93260000/93258000/93257980/c91d9e37_y.jpg) ### Thompson Houston, by Hyatt 10/10 Excellent "The staff, the size of the room and decor were outstanding." [](https://expedia.ca/Houston-Hotels-Thompson-Houston.h93257980.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "Clean room, staff was super helpful" [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Hyatt Place Houston Medical Center](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/a6f86b3d_y.jpg) ### Hyatt Place Houston Medical Center 10/10 Excellent "Yes everything was clean and comfortable. The staff was very friendly and helpful." [](https://expedia.ca/Houston-Hotels-Hyatt-Place-Houston-Medical-Center.h88130440.Hotel-Information) ## Find out more about Texas Medical Center ## Texas Medical Center Hotels Guide Expedia.ca offers a selection of 6799 hotels in Texas Medical Center. You are sure to find cheap deals and discount rates among them with our Best Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs. Expedia.ca will not only save you time, but also money when booking your stay at a hotel in Texas Medical Center. Making reservations so you can stay within your budget is easy with us. Expedia.ca even provides you with a map so you may find hotels in the Texas Medical Center neighborhood you prefer. Go ahead. Enter your travel dates to view the best offers on hotel rooms in Texas Medical Center, Houston now! ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Houston Museum District ](https://www.expedia.ca/3Star-Houston-Museum-District-Houston-Hotels.s30-n6164045-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Houston Museum District ](https://www.expedia.ca/5Star-Houston-Museum-District-Houston-Hotels.s50-n6164045-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Casino-Hotel.0-n553248635976007975-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Cheap-Hotels.0-n553248635976007975-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Luxury-Hotel.0-n553248635976007975-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Spa-Hotel.0-n553248635976007975-0-tSpaHotel.Travel-Guide-Filter-Hotels) - 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