Title: Book the Best Texas Medical Center Hotels with Early Check-in in 2025 from CA $112 | Expedia.ca [Texas Medical Center Travel Guide](https://expedia.ca/Houston-Texas-Medical-Center.dx6143504)[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Texas Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Texas-Medical-Center.d6143504.Car-Rental-Guide)[Texas Medical Center Vacations](https://expedia.ca/Texas-Medical-Center.d6143504.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/f4655cac96c82fca6c00f4ab3162178c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels with Early Check-in in Texas Medical Center, TX from CA $112 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Texas Medical Center Hotels with Early Check-in Tonight [Oct 4 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-10-04&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6143504&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Texas Medical Center Hotels with Early Check-in ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17100/17068/a6dc27f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/1000000/20000/17100/17068/d7349640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch Smart TV with satellite channels, TV, Netflix](https://images.trvl-media.com/lodging/1000000/20000/17100/17068/aaf3a3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17100/17068/fee0ee12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Houston Marriott South at Hobby Airport Southeast Houston 8.8/10 Excellent (1249) "Great stay, great rates and great location. " CA $127 CA $153 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Houston-Hotels-Houston-Marriott-South-At-Hobby-Airport.h17068.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2660000/2658700/2658694/aa4e2191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/3000000/2660000/2658700/2658694/ce57912a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2660000/2658700/2658694/02738a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/3000000/2660000/2658700/2658694/a8b9c078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Near Downtown North Northside 8.4/10 Very good (736) "Great place to stay at " CA $96 CA $112 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Houston-Hotels-Sleep-Inn-Suites-Near-Downtown-North.h2658694.Hotel-Information) ![Buffet breakfast on weekends (USD 18 per person)](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/ed52898c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/8942d8c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/e0bf3fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5900/5886/7db809e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Houston Hobby Airport Southeast Houston 8.8/10 Excellent (1000) "Great stay" CA $122 CA $143 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Houston-Hotels-Doubletree-By-Hilton-Houston-Hobby-Airport.h5886.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f2e085ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/12af8c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center Texas Medical Center 8.4/10 Very good (1611) "Very nice staff, enjoyed our stay" CA $138 CA $163 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/5cc6610b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/c3718846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/a3baec81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/7c625b2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Houston Marriott Medical Center/Museum District Texas Medical Center 9.0/10 Wonderful (1001) "Enjoyed the stay" CA $250 CA $338 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Houston-Hotels-Houston-Marriott-Medical-CenterMuseum-District.h16154.Hotel-Information) ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/9235e98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/026cb2a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/w3998h2667x2y0-ff5ca8a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Houston Medical Center/Museum District Texas Medical Center 9.0/10 Wonderful (1001) "Great place to stay. " CA $237 CA $295 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/a403ab12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/522c66f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/88ce8c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/2b2d8506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Houston Webster NASA Webster 9.0/10 Wonderful (1003) "Great hotel" CA $123 CA $144 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Houston-Hotels-Tru-By-Hilton-Houston-Webster-NASA.h27293821.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/480000/479200/479140/2bdcec19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/480000/479200/479140/6758c7ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/480000/479200/479140/e3b0daad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/479200/479140/098c9898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Houston/Clear Lake-Nasa Area Webster 8.4/10 Very good (1000) "great place to stay. good breakfast options and a good area to hang out in downstair in the front lobby" CA $101 CA $118 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Houston-Hotels-Hampton-Inn-Suites-HoustonClear-Lake-Nasa-Area.h479140.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/69d373fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/1ef7d119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/6bc32cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/f9e5bd86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Houston Intercontinental Arprt Houston 9.0/10 Wonderful (1497) "Nice room, convenient location, I enjoyed my stay. " CA $129 CA $151 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Houston-Hotels-SpringHill-Suites-By-Marriott-Houston-Intercontinental-Arprt.h2964240.Hotel-Information) ![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/25500/25440/a46f30d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/25500/25440/0a4a6147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/25500/25440/3a694db4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25500/25440/d255ab99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Houston I-10 West/Energy Corridor Memorial 8.6/10 Excellent (1001) "great location, really enjoyed our stay!" CA $122 CA $142 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Houston-Hotels-Courtyard-By-Marriott-Houston-I-10-WestEnergy-Corridor.h25440.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-18&endDate=2025-10-19®ionId=6143504&adults=2&property_amenities_group_explore=express_checkin&sort=RECOMMENDED&openPlayBack=true) ## Top Texas Medical Center Hotel Reviews ![Hilton Americas-Houston](//images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "Very beautiful hotel" [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](//images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "We stayed here with kids for Astros game. Loved the convenience to walk to Astros games, park downtown and metro! Lived the nightly complimentary milk and cookies. 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[Riverside Terrace Hotels](https://www.expedia.ca/Riverside-Terrace-Houston-Hotels.0-n151857-0.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Adults-Only-Resorts.0-n553248635976476176-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Casino Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Casino-Hotel.0-n553248635976476176-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Cheap-Hotels.0-n553248635976476176-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Hotels-With-Kitchenettes.0-n553248635976476176-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Luxury Hotels in South Central Houston](https://www.expedia.ca/South-Central-Houston-Houston-Hotels-Luxury-Hotel.0-n553248635976476176-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Budget Host Hotels in Southgate](https://www.expedia.ca/Southgate-Houston-Hotels-Budget-Host.0-n553248635976470716-0--bBudgetHost.Travel-Guide-Filter-Hotels) - [Southgate Hotels](https://www.expedia.ca/Southgate-Houston-Hotels.0-n553248635976470716-0.Travel-Guide-Filter-Hotels) - [Aparthotels in Stadium Park/Astrodome Station](https://www.expedia.ca/Stadium-ParkAstrodome-Station-Apart-Hotels.d6211680-aaApartHotels.Travel-Guide-Accommodation) - [Hostels in Stadium Park/Astrodome Station](https://www.expedia.ca/Stadium-ParkAstrodome-Station-Hostels.d6211680-aaHostels.Travel-Guide-Accommodation) - [Hotels near Stadium Park/Astrodome Station](https://www.expedia.ca/Stadium-ParkAstrodome-Station-Hotels.d6211680.Travel-Guide-Hotels) - [Farmstay in TMC Transit Center](https://www.expedia.ca/TMC-Transit-Center-Agritourism.d6211673-aaAgritourism.Travel-Guide-Accommodation) - [Hotels near Texas Children's Hospital](https://www.expedia.ca/Texas-Childrens-Hospital-Hotels.0-l553248635389801905-0.Travel-Guide-Filter-Hotels) - [University Place Hotels](https://www.expedia.ca/University-Place-Houston-Hotels.0-n553248635976386985-0.Travel-Guide-Filter-Hotels) - [Flights to Houston](https://www.expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights) - [Cullen Sculpture Garden](https://www.expedia.ca/Cullen-Sculpture-Garden-South-Central-Houston.d6237440.Vacation-Attraction) - [Hermann Park](https://www.expedia.ca/Hermann-Park-South-Central-Houston.d507227.Vacation-Attraction) - [Visit Astrodome](https://www.expedia.ca/Houston-Astrodome.dx553248635976007975) - [Houston Museum of Fine Arts](https://www.expedia.ca/Houston-Museum-Of-Fine-Arts-South-Central-Houston.d501255.Vacation-Attraction) - [James Turrell's Twilight Epiphany Skyscape](https://www.expedia.ca/James-Turrells-Twilight-Epiphany-Skyscape-South-Central-Houston.d553248621532644481.Vacation-Attraction) - [Md Anderson Cancer Center](https://www.expedia.ca/MD-Anderson-Cancer-Center-Texas-Medical-Center.d6248539.Vacation-Attraction) - [Nrg Stadium](https://www.expedia.ca/NRG-Stadium-Astrodome.d553248635929331916.Vacation-Attraction) - [Car rentals near Houston Museum District](https://www.expedia.ca/Car-Rentals-In-Houston-Museum-District.d6164045.Car-Rental-Guide) - [Things to do in Houston](https://www.expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities) - [Book Hotels in Texas Medical Center on Expedia.com](https://www.expedia.com/Texas-Medical-Center-Houston-Hotels-Hotel-With-Early-Check-In.0-n6143504-0-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)