Santa Rosa Vacation Rentals

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Our top choices for Santa Rosa vacation rentals

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (17 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
Linda Vista Cabins

Aires frescos de Boquete

Aires frescos de Boquete
2.0 star property
Alto Boquete
9.0 out of 10, Wonderful, (4 reviews)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
The price is CA $71
CA $78 total
includes taxes & fees
Mar 30 - Mar 31
Aires frescos de Boquete

Lucero - Luxury Treehouses

Lucero - Luxury Treehouses
3.5 star property
Jaramillo
8.8 out of 10, Excellent, (5 reviews)
"Print or save your map beforehand. Do not exit onto a gravel road! The property is located inside a golf community. The map on the listing is incorrect! As of October 2025 all maps including Google, Waze and Apple maps all have the wrong and remote location. The correct location is Lucero. We had a beautiful experience! Everyone was so pleasant and welcoming. We had an amazing stay!"
United States
John
The price is CA $324
CA $356 total
includes taxes & fees
Mar 30 - Mar 31
Lucero - Luxury Treehouses

Casa Little Italy

Casa Little Italy
3.0 star property
Tijeras
6.0 out of 10, (1 review)
"Didn't accept credit card payment "
Mexico
ANGELO
The price is CA $95
CA $104 total
includes taxes & fees
Mar 27 - Mar 28
Casa Little Italy

Casa Mate by Villa Alejandro

Casa Mate by Villa Alejandro
3.5 star property
Los Naranjos
6.0 out of 10, (2 reviews)
The price is CA $88
CA $123 total
includes taxes & fees
Apr 26 - Apr 27
Casa Mate by Villa Alejandro

Casa Reina by Villa Alejandro

Casa Reina by Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (19 reviews)
"Be aware the road, or trail more like it, to the hotel is very rough, only 1 lane in same areas. Check in took 15 minutes, with remote concierge. Views from balcony is great. Grounds are well kept. lots of small birds singing. Room is large and king bed is comfortable."
United States
Tim
The price is CA $109
CA $146 total
includes taxes & fees
Apr 22 - Apr 23
Casa Reina by Villa Alejandro

Volcano View Cottage

Volcano View Cottage
Volcán
9.4 out of 10, Exceptional, (3 reviews)
"I was alone, but this casita would be perfect for a couple. The owner, Antonio, was quick to respond to any issues. I would definitely stay there again."
United States
John E.
The price is CA $96
CA $124 total
includes taxes & fees
Mar 27 - Mar 28
Volcano View Cottage

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
3.0 star property
El Tropezón
The price is CA $140
CA $287 total
includes taxes & fees
Apr 22 - Apr 23
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

Villa Alejandro

Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (143 reviews)
"We enjoyed the clean common areas, coffee, water and friendly staff. The room was small but adequate. Bathroom was very small and clean"
Canada
norma
The price is CA $77
CA $115 total
includes taxes & fees
Apr 16 - Apr 17
Villa Alejandro

Peace N' Green

Peace N' Green
3.0 star property
David
The price is CA $124
CA $136 total
includes taxes & fees
Mar 27 - Mar 28
Peace N' Green

Downtown Suites

Downtown Suites
3.0 star property
El Tropezón
9.0 out of 10, Wonderful, (105 reviews)
"Construction noise, but they stopped working at 6pm so didn't affect us much as we stayed for 1 night "
Canada
Alexandr
Downtown Suites

Aparthotel Los Pinos

Aparthotel Los Pinos
2.5 star property
Boquete
8.6 out of 10, Excellent, (17 reviews)
"The place was spacious, clean and comfortable. Great location and easy parking."
United States
Rebecca
The price is CA $164
CA $180 total
includes taxes & fees
Mar 27 - Mar 28
Aparthotel Los Pinos

El Cielo by Villa Alejandro

El Cielo by Villa Alejandro
3.5 star property
Boquete
9.4 out of 10, Exceptional, (104 reviews)
"Everything was perfect! The room was comfortable and clean. The proximity to town was great!Communication with the hosts was excellent!"
United States
Lee
El Cielo by Villa Alejandro

Residencial Lassonde Guest House, David

Residencial Lassonde Guest House, David
David
The price is CA $87
CA $122 total
includes taxes & fees
Mar 29 - Mar 30
Residencial Lassonde Guest House, David

Cabin in Cerro Punta 6BR, Fireplace, Hiking

Cabin in Cerro Punta 6BR, Fireplace, Hiking
Cerro Punta
The price is CA $642
CA $730 total
includes taxes & fees
Mar 27 - Mar 28
Cabin in Cerro Punta 6BR, Fireplace, Hiking

MOMA GuestHouse Alto Boquete - Double Room

MOMA GuestHouse Alto Boquete - Double Room
Alto Boquete
The price is CA $76
CA $114 total
includes taxes & fees
Mar 29 - Mar 30
MOMA GuestHouse Alto Boquete - Double Room

Cabañas Mountain View, near to the national park Volcan Baru

Cabañas Mountain View, near to the national park Volcan Baru
Volcán
8.0 out of 10, Very good, (1 review)
"Basic but nice small cottage which was perfect for relaxing near Volcan."
United States
Paquita B.
The price is CA $96
CA $140 total
includes taxes & fees
Mar 27 - Mar 28
Cabañas Mountain View, near to the national park Volcan Baru

MOMA Guest House in Alto Boquete - Family Room

MOMA Guest House in Alto Boquete - Family Room
Alto Boquete
9.0 out of 10, Wonderful, (2 reviews)
"Very practical, clean property on Via Boquete. Walking distance to El Sabroson #4 restaurant with fantastic local food. Groceries and other shopping nearby. Common kitchen, dining and hang out areas were clean and accessible. Host was very responsive. Thanks for a great stay!"
United States
mercedes
The price is CA $98
CA $137 total
includes taxes & fees
Apr 7 - Apr 8
MOMA Guest House in Alto Boquete - Family Room

Copeyhousechiriquí

Copeyhousechiriquí
Volcán
The price is CA $68
CA $107 total
includes taxes & fees
Apr 6 - Apr 7
Copeyhousechiriquí

Independent room

Independent room
David
The price is CA $26
CA $54 total
includes taxes & fees
Mar 29 - Mar 30
Independent room
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Rosa Hotel Reviews

Find out more about Santa Rosa

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Rosa. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Santa Rosa?

Yes, we give you a choice of vacation rentals near popular local attractions in Santa Rosa, or you can choose a more remote option if you're looking for relaxation.

What are some of the best vacation home rentals in Santa Rosa?

Homely 3-bedroom house in gorgeous Alto Boquete neighborhood: This vacation home rental outside of Santa Rosa comes with laundry facilities so you can feel at home during your trip. Kitchen amenities like a stovetop and a microwave can make your vacation run smoothly.

What’s there to see and do in Santa Rosa?

While you're exploring the area, Las Cavernas de Corredores and Finca Dracula Orchid Sanctuary are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Finca Lérida Coffee Estate and Barriles.

What’s a vacation rental in Santa Rosa like?

A vacation rental is a private property you can stay in for a long or short time in Santa Rosa. Vacation rentals offer amenities such as kitchens and laundry facilities so you'll have everything you need. If you're concerned about a sanitized environment, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for a family getaway.