Santa Isabel Vacation Rentals

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Our top choices for Santa Isabel vacation rentals

Casa Palma Serena - Garden Retreat • Tropical Stay

Casa Palma Serena - Garden Retreat • Tropical Stay
Santa Isabel
10.0 out of 10, Exceptional, (2 reviews)
"Our host was very accommodating! The home was beautiful "
United States
Sally R.
The price is CA $226
CA $489 total
includes taxes & fees
Jun 8 - Jun 9
Casa Palma Serena - Garden Retreat • Tropical Stay

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2
Santa Isabel
10.0 out of 10, Exceptional, (2 reviews)
"We enjoyed our stay immensely. The bed was very comfortable. We loved the outdoor spaces. The parking was a little hard to figure out at first. We loved sitting by the water’s edge with morning coffee and evening glass of wine. "
United States
Penny O.
The price is CA $237
CA $669 total
includes taxes & fees
May 17 - May 18
Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
8.8 out of 10, Excellent, (48 reviews)
"Very nice,on the ocean,steps to beach need repair"
United States
James
The price is CA $275
CA $499 total
includes taxes & fees
May 24 - May 25
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Coming and enjoy panoramic views to mountains and sea in Santa Isabel
Santa Isabel
10.0 out of 10, Exceptional, (1 review)
"This is a unique property with beautiful views. The hosts were incredibly helpful and responsive!"
United States
Annie H.
The price is CA $248
CA $466 total
includes taxes & fees
May 17 - May 18
Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Santa Isabel
10.0 out of 10, Exceptional, (4 reviews)
"Great host communication, central location, lovely home. "
United States
Scott P.
The price is CA $355
CA $754 total
includes taxes & fees
May 19 - May 20
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

La Gozadera Park

La Gozadera Park
1.0 star property
Salinas
10.0 out of 10, Exceptional, (2 reviews)
The price is CA $186
CA $202 total
includes taxes & fees
May 17 - May 18
La Gozadera Park

The Place at the Sea

The Place at the Sea
3.0 star property
Ponce
9.4 out of 10, Exceptional, (336 reviews)
"Great little, peaceful spot - owner is helpful and friendly."
United States
Adrielle
The price is CA $79
CA $86 total
includes taxes & fees
May 27 - May 28
The Place at the Sea

Oasis Salinas

Oasis Salinas
Salinas
7.8 out of 10, Good, (13 reviews)
"Excellent place to stay near everything in town "
United States
Mayra
The price is CA $131
CA $189 total
includes taxes & fees
May 17 - May 18
Oasis Salinas

Grandpa's lake house lake private access mountain view museum 1950's experience

Grandpa's lake house lake private access mountain view museum 1950's experience
Cidra
9.4 out of 10, Exceptional, (6 reviews)
"We had a great peaceful visit!"
United States
Kelly N.
The price is CA $97
CA $160 total
includes taxes & fees
May 17 - May 18
Grandpa's lake house lake private access mountain view museum 1950's experience

HW Tiny Home Cidra

HW Tiny Home Cidra
Cidra
10.0 out of 10, Exceptional, (2 reviews)
"Beautiful area, great AC, clean hot tub, lovely acces to lake with paddleboat!"
United States
Elizabeth C.
The price is CA $161
CA $260 total
includes taxes & fees
May 18 - May 19
HW Tiny Home Cidra

Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony

Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony
Barranquitas
10.0 out of 10, Exceptional, (3 reviews)
"great stay super clean and comfy"
United States
frankie q.
The price is CA $179
CA $233 total
includes taxes & fees
May 17 - May 18
Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony

Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

Cozy studio with private Pool and Bar modern amentities perfect for relaxation.
Cidra
8.4 out of 10, Very good, (6 reviews)
"We have a wonderful time! The pool and bar were perfect!"
United States
Anna D.
The price is CA $155
CA $354 total
includes taxes & fees
May 18 - May 19
Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.

Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.
Guayama
10.0 out of 10, Exceptional, (2 reviews)
"Property was so beautiful didn’t have any complains. Everything you need in one spot you’d never want to leave."
United States
Jonathan
The price is CA $173
CA $273 total
includes taxes & fees
May 29 - May 30
Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.

Trinitarias Guest's House's pool/bar/karaoke/wifi

Trinitarias Guest's House's pool/bar/karaoke/wifi
Salinas
10.0 out of 10, Exceptional, (3 reviews)
"Felt like home beautiful super clean quiet I will definitely be back to this home in our vacations Host is amazing Thank You for sharing this beautiful house with my family "
United States
julio
The price is CA $124
CA $248 total
includes taxes & fees
Jun 1 - Jun 2
Trinitarias Guest's House's pool/bar/karaoke/wifi

Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR

Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR
Coamo
7.0 out of 10, Good, (2 reviews)
"Spotless cozy , ice cold air"
United States
Alberto
The price is CA $87
CA $194 total
includes taxes & fees
May 18 - May 19
Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR

RED LOFT VIBE WALKING DISTANCE TO THE CITY

RED LOFT VIBE WALKING DISTANCE TO THE CITY
Guayama
9.6 out of 10, Exceptional, (5 reviews)
"The best place to spend your days if you visit the city of Guayama, easy access to all the sites of interest in the area."
United States
Hector
The price is CA $105
CA $169 total
includes taxes & fees
May 17 - May 18
RED LOFT VIBE WALKING DISTANCE TO THE CITY

Nostra Casa Vagón

Nostra Casa Vagón
Coamo
10.0 out of 10, Exceptional, (1 review)
"Everything was very clean and organized I got confused with the address and the owner communicated with me and directed me to the exact address when I go to Puerto Rico again I will contact them again to stay at the same place "
United States
Carlos Reyes
The price is CA $87
CA $194 total
includes taxes & fees
May 18 - May 19
Nostra Casa Vagón

Points Apartments

Points Apartments
Guayama
9.4 out of 10, Exceptional, (3 reviews)
"Great property great people"
United States
Julian
The price is CA $172
CA $289 total
includes taxes & fees
May 19 - May 20
Points Apartments

Tiny Cozy Mountain Cabin Peaceful Retreat in Cayey

Tiny Cozy Mountain Cabin Peaceful Retreat in Cayey
Cayey
8.0 out of 10, Very good, (1 review)
The price is CA $83
CA $211 total
includes taxes & fees
May 24 - May 25
Tiny Cozy Mountain Cabin Peaceful Retreat in Cayey

A cozy place to stay walking distance from the beach and Restaurants.

A cozy place to stay walking distance from the beach and Restaurants.
Salinas
9.4 out of 10, Exceptional, (26 reviews)
"Complete kitchen, fairly quiet area, near great restaurants "
United States
John W.
The price is CA $87
CA $194 total
includes taxes & fees
Jun 2 - Jun 3
A cozy place to stay walking distance from the beach and Restaurants.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Find out more about Santa Isabel

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Isabel. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, there are vacation rentals close to the most popular attractions in Santa Isabel, or you can choose a secluded option if you're looking for relaxation. Santa Isabel is known for its shopping and restaurants. Make sure you have time to check out the beaches while you're in the area.

What's the top vacation rental that Santa Isabel has to offer?

3BR Puerto Rico Villa w Pool | Aqua Bella 1: This highly rated vacation home rental in Santa Isabel is located by the ocean and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. Our travelers also rate Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep as a favorite home for rent in Santa Isabel.

How many vacation rentals will I find in Santa Isabel?

Expedia has 7 vacation rentals for your stay in Santa Isabel.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Museo de la Musica Puertorriquena, or get out into nature at a spot like Playa La Ochenta. Carribbean Cinemas Santa Isabel and Coamo Springs are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Isabel?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Santa Isabel. Vacation rentals offer extras like WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular option for a family trip.